This group also focuses on developing affordable sensors for a wide range of applications, such as detecting metal ions, moisture, pH and pollutants like pesticides, polyfluoro compounds and organic pollutants. To achieve this, we use a variety of techniques such as paper sensors, fluorescent sensors and spectroscopic techniques like spectrophotometry and spectrofluorometry. We also use calorimetric techniques like isothermal titration calorimetry (ITC) and quantum chemical calculations to optimize the sensor's performance. We are particularly interested in developing low-cost sensors that can be used in various fields such as environmental monitoring, medical diagnostics and food and water quality testing. Our goal is to make these sensors widely available and accessible to a wide range of users, and to provide a reliable and easy-to-use solution for detecting various chemical compounds.

PFASs are non-degradable pollutants found globally in our environment and in humans. PFAS exposure has been linked to metabolic and developmental disorders, as well as disease. This work aims to determine the molecular mechanisms that lead to protein binding and lipid partitioning under environmentally and physiologically relevant conditions. With over 5,000 known PFASs present in the environment, molecular mechanisms are needed to predict bioaccumulation and biodistribution. Our research interest is also focused on studying the effect of various natural products and environmental pollutants on protein aggregation. To accomplish this, we are utilizing several analytical techniques such as fluorescence, isothermal titration calorimetry (ITC), circular dichroism (CD), infrared (IR), and Raman spectroscopy. Through these methods, we aim to investigate the changes in the conformational stability and aggregation propensity of the protein in response to exposure to different natural products and environmental pollutants. This research has important implications for understanding the mechanisms underlying protein aggregation and identifying potential strategies for preventing or mitigating this phenomenon in various disease states. Furthermore, your work may have broader implications for developing new approaches for studying the effects of environmental pollutants on biological systems.

My research group focuses on the extraction and isolation of phytochemicals from medicinally active plants with ethnomedical history, specifically targeting indigenous Indian plant species. Considering the growing threat of bacterial resistance to antibacterial and antifungal drugs we are particularly interested in the antimicrobial and antifungal properties of these phytochemicals. Finding phytochemicals that can control protein aggregation is also on top priority list of our group. We believe that these plants have a wealth of potential therapeutic compounds and our research aims to uncover and study these compounds in order to develop new treatments for various diseases.