The Mendero family started its 19 year experience in the hospital industry in Pagadian City. Its first hospital started as Sto. Nino Clinic, which was a 10 bed primary care institution. After a few years of operation, Dr. Samuel J. Mendero decided to build Pagadian City Medical Center in 1996, pioneering the delivery of quality health care in the province of Zamboanga del Sur. As of today, it is still the only tertiary hospital in the Zamboanga Del Sur, making it the primary private health care provider in the Zamboanga peninsula outside of Zamboanga City.

In 2013, Dr. Samuel J. Mendero and family felt that Pagadian City Medical Center has already reached its maximum potential. After much research and feasibility studies, the Mendero Corporation decided to build another hospital in Consolacion, Cebu. In November 2010, Dr. Samuel J. Mendero and family started the construction of the Mendero Medical Center. It finally started its operations in February 6, 2014. The hospital has been growing since then by slowly improving and innovating its processes, updating its equipment and recruiting the most passionate doctors that are at the same time loyal to the patients specially those coming from the north of Cebu.

Currently, the Mendero Medical Center is a 250 bed tertiary hospital located in Consolacion, Cebu. Currently, the hospital is operating with 100 DOH licensed beds. After more than a year of operation, the hospital has an average of 50 to 70 in-patients daily. The variety of cases present in the hospital at any given time is also very conducive for a family medicine training.

The growing demands for holistic care has kindled to start a training program in the hospital. Thus last October 2015 the Department of Family and Community Medicine was opened with its practiced based residency training program spear headed by its chairman Dr. Annabelle C. Fuentes, MD, FPAFP and training officers, Leida Marie P. Alarcon, MD, DFM and Ruth C. Andal, MD, DFM.