Embedded Files
DNA model Assembly
About
About
A DNA molecule consists of 4 different nucleotides. Each nucleotide consists of 3 components. A phosphate group, deoxyribose sugar, and a nitrogenous base. The 4 different nitrogenous bases (Adenine, Thymine, Cytosine, and Guanine) allow for the variability found within DNA.
IN DNA the thymine always connects with the adenine and cytosine always pairs with guanine.
This is shown in our puzzle and we use different shapes to form the connection.
Parts
Parts
The Tactile DNA puzzle is a tool to teach visually impaired students the chemistry and structure of DNA. Our puzzle contains the 4 different nucleotides (A,T,C,G) a phosphate piece and Deoxyribose piece.
Adenine
Thymine
Guanine
Cytosine
Phosphate
Deoxyribose
Print Settings:
Print Settings:
Layer Height: 0.20 mm
Initial Layer Height: 0.20 mm
Number of Walls: 2
Number of Top Layers: 4
Number of Bottom Layers: 4
Infill: 25 %
Supports: Everywhere, 75% angle
Bed Adhesion: Raft
Estimated Print Time: 50 minutes
Print Weight: 9 grams
Print Size (X,Y,Z): 71.9 x 4.2, 68.8 mm
Enable Retraction: Yes
Download:
Download:
A Kit consists of the following parts:
Deoxyribose: 8 pieces
Phosphate: 8 pieces
Adenine: 2 pieces
Thymine: 2 pieces
Cytosine: 2 pieces
Guanine: 2 pieces
Instructions
Instructions
Take a deoxyribose piece (Pentagon) and a Phosphate piece (L shaped piece)
Connect the Phosphate to the Deoxyribose piece on the groove labeled 3’ The phosphate should be facing out and all of the letters should face the same direction
Repeat the above steps 8 times
Take a completed deoxyribose-phosphate piece and connect a base pair to a round circular hole. There are 4 different times of base pairs creating 4 different types of nucleotides. Completed models are shown below
Adenine Nucleotide
Thymine Nucleotide
Cytosine Nucleotide
Guanine Nucleotide
5. Now you should have 8 different nucleotides. 2 adenine nucleotides, 2 guanine nucleotides, cytosine nucleotides, and 2 thymine nucleotides.
6. Take an adenine nucleotide and a cytosine nucleotide and connect the A and T piece
7. Take a cytosine nucleotide and a guanine nucleotide and connect the C and G piece
8. Repeat steps 6 and 7.
9. Connect the Phosphates to the 5’ spot of the next deoxyribose molecule
A-T Connection
A-T Connection
C-G Connection
C-G Connection
Activites
Activites
How many different chains of DNA can be created with 4 base pairs?
How many different chains of DNA can be created with 4 base pairs?
In order to calculate the possible combinations we use factorials (!). 4 factorial or 4! is 4 * 3 * 2 * 1 = 24. This means there are 24 different arrangements of 4 nucleotides. Create all 24 combinations!
Class wide / Grade wide / School wide Project
Class wide / Grade wide / School wide Project
Each student has four base pairs and creates any combination of nucleotides they would like; A, T, C, G.
Each student places down their four base pairs and connects them (or a teacher because of Covid) to each other. 20 students is 80 base pairs! 100 students is 400 base pairs.
Connect over many tables or attach along a hallway wall.
Explore how only four letters can produce an enormous amount of genetic information.
How long is a real DNA strand?
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