Publications

J. K. Lee, H. N. Lee, S. Agrawal, J. A. Balsamo, A. Clerman, S. Denies, A. De Groot, J. Fry, N. Gaudenzio, A. J. Graves, K. E. Howard, S. J. Hwang, V. Jawa, Y. Jin, L. Kelly-Baker, E. Knowlton, F. Kolenc, K. K. Sivakumar, J. H. Lee, Y. Li, L. Liang, D. Liu, Y. Liu, R. Lionberger, M. C. Luke, M. Manangeeswaran, M. Mendoza, I. Murphy, M. Norcross, J. E. Polli, M. Puig, N. Rao, H. Rogers, A. Schwendeman, R. Siegel, S. Shubow, N. Smith, S. G. Thacker, S. Tourdot, K. Yang, L. Zhang, D. Zhang, C. J. Smith, E. S. Pang, and Daniela Verthelyi. Proceedings of the 2024 FDA-CRCG Workshop: Scientific and Regulatory Considerations for Assessment of Immunogenicity Risk for Generic Peptide and Oligonucleotide Drug Products. AAPS J, 28:61, 2026 (DOI)

R. L. Walenga, S. G. Chopski, J. H. Lee, F. Wang, M. Hu, A. H. Babiskin, L. Fang, and L. Zhao. Using lung regional deposition modeling as model-integrated evidence for locally acting orally inhaled drug products. Pharm Res, 42:1917-1930, 2025 (DOI)

L. Li, C. Gruninger, J. H. Lee, and B. E. Griffith. Volume conservation and stability improvements of composite B-spline kernels in the immersed boundary method. Adv Comput Sci Eng, 4:16-56, 2025 (DOI, arXiv)

J. Wang, G. Campbell, J. H. Lee, M. Hu, K. Feng, S. Chattopadhyay, L. Zhao, and C. Peck. Bioequivalence of ANDA data using a non-informative Bayesian procedure (BEST) compared with the two one-sided t-tests (TOST). AAPS J, 27(2), 47, 2025 (DOI)

D. Wells, B. Vadala-Roth, J. H. Lee, and B. E. Griffith. A nodal immersed finite element-finite difference method. J Comput Phys, 477:111890 (29 pages), 2023 (DOI, arXiv)

J. A. Brown, J. H. Lee, M. A. Smith, A. Barrett, C. Puelz, J. P. Vavalle, and B. E. Griffith. Patient-specific immersed finite element-difference model of transcatheter aortic valve replacement. Ann Biomed Eng, 51(1):103-116, 2023 (Open Access Publication, Supplemental Material, DOI, SharedIt)

S. Kuhar, J. H. Lee, J.-H. Seo, P. J. Pasricha, and R. Mittal. Effect of stomach motility on food hydrolysis and gastric emptying: Insights from computational models. Phys Fluids, 34(11):111909, 2022 (Featured & Scilight Article) (DOI, arXiv, Scilight) 

J. H. Lee, S. Kuhar, J.-H. Seo, P. J. Pasricha, and R. Mittal. Computational modeling of drug dissolution in the human stomach: Effects of posture and gastroparesis on drug bioavailability. Phys Fluids, 34(8):081904 (17 pages), 2022 (Featured Article) (DOI, arXiv)

J. H. Lee and B. E. Griffith. On the Lagrangian-Eulerian coupling in the immersed finite element/difference method. J Comput Phys, 457:111042 (23 pages), 2022 (DOI, arXiv)

J. H. Lee, L. N. Scotten, R. Hunt, T. G. Caranasos, J. P. Vavalle, and B. E. Griffith. Bioprosthetic aortic valve diameter and thickness are directly related to leaflet fluttering: Results from a combined experimental and computational modeling study. JTCVS Open. 6:60-81, 2021 (Open Access Publication, DOI)

J. H. Lee, A. D. Rygg, E. M. Kolahdouz, S. Rossi, S. M. Retta, N. Duraiswamy, L. N. Scotten, B. A. Craven, and B. E. Griffith. Fluid-structure interaction models of bioprosthetic heart valve dynamics in an experimental pulse duplicator. Ann Biomed Eng, 48(5):1475–1490, 2020 (One of top ABME papers in 2020) (Open Access Publication, Supplemental Material, DOI, engrXiv)

​J. H. Lee, Y. Yao, U. Shrestha, G. T. Gullberg, and Y. Seo. Handling big data in medical imaging: iterative reconstruction with large-scale automated parallel computation, IEEE Nucl Sci Symp Conf Rec (1997). 2014 Nov; 2014. PMID: 27081299 (PubMed)

J. H. Lee, H. Gao, M. Döllinger. Editorial: Integrating machine learning with physics-based modeling of physiological systems. Front Physiol, 16:1562750, 2025 (DOI)

S. Y. Huang, J. H. Lee, H. Pan, R. Boutchko, U. Shrestha, G. T. Gullberg, D. Mitra, Y. Yao, and Y. Seo, High performance fully 3D and 4D image reconstruction in SPECT using a big data analytic tool running on a supercomputer. The 13th International Meeting on Fully Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine (Fully-3D), Newport, Rhode Island, USA, 2015.

J. H. Lee. Simulating In Vitro Models of Cardiovascular Fluid-Structure Interaction: Methods, Models, and Applications. PhD thesis, University of North Carolina at Chapel Hill, 2020 (DOI)