Publications

2020

Morgan MD, Patin E, Jagla B, Hasan B, Quintana-Murci L, Marioni JC (2020) Quantitative genetic analysis deciphers the impact of cis and trans regulation on cell-to-cell variability in protein expression levels, PLoS Genetics. https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1008686

Baran-Gale J, Morgan MD, Maio S, Dhalla F, Calvo-Asensio I, Deadman M, Handel AE, Maynard A, Chen S, Green F, Sit R, Neff N, Damanis S, Tan W, May AP, Marioni JC, Ponting CP, Holländer GA (2020) Ageing compromises mouse thymus function and remodels epithelial cell differentiation, eLife. https://elifesciences.org/articles/56221

2019

Eling N, Morgan MD, Marioni JC (2019) Challenges in measuring and understanding biological noise, Nature Reviews Genetics. https://www.nature.com/articles/s41576-019-0130-6

2018

Morgan MD, Pairo-Castineira, Rawlik K, Canela-Xandri O, Ress J, Sims D, Tenesa A, Jackson I (2018) Genome-wide study of hair colour in UKBiobank explains most of the SNP heritability, Nature Communications. https://www.nature.com/articles/s41467-018-07691-z

Morgan MD & Marioni JC (2018) CpG island composition differences are a source of gene expression noise indicative of promoter responsiveness, Genome Biology. https://genomebiology.biomedcentral.com/articles/10.1186/s13059-018-1461-x

John C Taylor, Tim Bongartz, Jonathan Massey, Borbala Mifsud, Athina Spiliopoulou, Ian C Scott, Jianmei Wang, Michael Morgan, Darren Plant, Marco Colombo, Peter Orchard, Sarah Twigg, Iain B McInnes, Duncan Porter, Jane E Freeston, Jackie L Nam, Heather J Cordell, John D Isaacs, Jenna L Strathdee, Donna Arnett, Maria JH de Hair, Paul P Tak, Stella Aslibekyan, Ronald F van Vollenhoven, Leonid Padyukov, S Louis Bridges, Costantino Pitzalis, Andrew P Cope, Suzanne MM Verstappen, Paul Emery, Michael R Barnes, Felix Agakov, Paul McKeigue, Taisei Mushiroda, Michiaki Kubo, Richard Weinshilboum, Anne Barton, Ann W Morgan, Jennifer H Barrett (2018) Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients, The Pharmacogenomics Journal. https://www.nature.com/articles/s41397-018-0025-5

Haghverdi L, Lun ATL, Morgan MD, Marioni JC (2018) Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbours, Nature Biotechnology. https://www.nature.com/articles/nbt.4091?draft=journal

Joannah R Fergusson, Michael Morgan, Melanie Bruchard, Leonie Huitema, Vincent van Uden, Jan-Piet van Hamburg, Nicole van der Wel, Daisy Picavet, Sander Tas, Frits Koning, Mark Anderson, John Marioni, Georg Hollander, Hergen Spits (2018) Maturing human CD127+CCR7+PDL1+ dendritic cells expression AIRE in the absence of tissue restricted antigens, Frontiers in Immunology. https://www.frontiersin.org/articles/10.3389/fimmu.2018.02902/abstract

2016

Chambers TJG, Morgan MD, Heger AH, Sharpe RM, Drake AJ (2016) High-fat diet disrupts metabolism in two generations of rats in a parent-of-origin specific manner, Scientific Reports. https://www.nature.com/articles/srep31857

2014

Morgan M.D., Al-Shaarawy N., Martin S., Robinson J.I., Twigg S., YEAR Consortium, Magdy A.A., Omar A.S., Ghattas M.H., Emerpy P., Barrett J.H., & Morgan A.W. (2014) MTHFR functional genetic variation and methotrexate treatment response in rheumatoid arthritis: A meta-analysis, Pharmacogenomics. https://www.futuremedicine.com/doi/abs/10.2217/pgs.13.235

2013

Teare M.D., Knevel R., Morgan M.D., Kleszcz A., Emery P., Moore D.J., Conaghan P.G., Huizinga T.W.J., Morgan A.W., van der Helm-van Mil A.H.M., & Wilson A.G. (2013) Allele dose association of the C5orf30 rs26232 variant with joint damage in rheumatoid arthritis, Arthritis & Rheumatism. https://onlinelibrary.wiley.com/doi/abs/10.1002/art.38064