Science / academic work

My research is driven by fundamental problems in biology and (bio)medicine, with a focus on building quantitative, predictive models. Projects in my research lab incorporate multi-scale modelling and simulations, artificial intelligence (AI),  bioengineering, and both microbiology and molecular biology tools to investigate: (1) host-microbiota interactions in complex human diseases, (2) microbial multi-drug resistance, and (3) gene expression and chromatin organization. In addition, we study the role and effect of mechanical forces ('mechanicanobiology') and cell compartmentalization in pathogenesis.

In my work, I combine cutting edge modeling and simulation techniques with experimental design and analysis of experimental data. This data includes DNA/RNA/ATAC/ChIP-seq, metabolomics, proteomics, super-resolution microscopy and more. Many of the questions I address involve the integration of these data into fully calibrated models that have predictive power, revealing testable experiments in fundamental biology and translational research, primarily aimed at identifying effective biomarkers and viable precision therapeutics.

Consulting

Other than science, I also trained in International Business Management. I am licensed to consult and have assisted organizations in various ways, such as negotiation, mediation and change management.