You know the kind of curious kid who dismantles broken machines to see “how it's done inside”, tries to identify the source of the malfunction, fiddles with the circuits in an attempt to fix it before reassembling everything in the fervent hope that it will work again? That's kind of what we're like in my taskforce, which is part of Ede Rancz's lab situated at the Mediterranean Institute of Neurobiology (Aix-Marseille University), an architectural jewel with the spectacular Parc des Calanques as a backdrop: we investigate how specific glutamatergic and GABAergic microcircuits are involved in neurological disorders of genetic or environmental origin (e.g., epilepsy, schizophrenia, autism). To this end, we use mice models of neurological disease as well as a combination of in vitro and in vivo electrophysiological strategies, calcium imaging, manipulation stratergies such as chemogenetics, and behavioral testing.