MAxillofacial bone Regeneration by 3D-printed laser-activated Graphene Oxide Scaffolds
We aim to create a breakthrough technology that allows precise mimicking of damaged bone and controllable deposition of extracellular matrix components together with high yield in terms of cell growth and differentiation and efficient antibacterial action
Defect modelling by 3D CAD and Bone Atlas Construction
3D printing and characterization of graphene scaffolds
3D printing of scaffolds resembling bone defects architecture and mechanical and morphological characterization.
Laser patterning and characterization
Optimization of conditions for scaffold activation through laser-induced reduction and surface wrinkling
In vitro biofunctionality tests
Biocompatibility assessment, evaluation of bacterial infection inhibition, bone regeneration promotion and vascularization capability in vitro
Multifunctional 3D printer prototype construction
Construction of a 3D printer prototype that incorporates Bone Atlas Fused Deposition Modelling (FDM) unit, an Injection Volume Filling (IVF) unit and a laser printing unit.