Research

Teaching Assistant, Sorbonne University (Paris)

My main research area are focused on :

1. membrane trafficking
2. Physical properties of membrane
3. Membrane proteins
4. Proteins interacting with membranes

My goal in research is to answer to biological question related to membrane and trafficking by using an approach, and a methodology related to physic. I usually use in vitro approach of artificial model membrane to precisely control all the important physical parameters such as membrane tension, membrane composition, salt concentration.

Since 2014, I am mostly interested in two classes of proteins:

(i) The Endosomal Sorting Complex Required for Transport-III (ESCRT-III) proteins that are involved in several remodeling membrane processes that required membrane fission (such as cytokinesis)

(ii) The septins. Septins are filamentous proteins involved in the last step of cytokinesis. They interact with and remodel the membrane.

We recently publish a paper in Nature Communication where we found that septins are sensitive to curvature. They avoid positive curvature and bent along negative curvature of 1/2 uM curvature. (Beber et al. Nature Comm, 2019).