Genomics and Infection

Cystic Fibrosis Physiopathology and Phenogenomics

St-Antoine Research Center, Paris, France

Brax et al. Eur J Cell Biol. 2024

Ruffin et al. Front immunol. 2021.

Last publications

Sylvain Brax, Clémence Gaudin , Claire Calmel , Pierre-Yves Boëlle , Harriet Corvol , Manon Ruffin , Loïc Guillot. Septin-dependent defense mechanisms against Pseudomonas aeruginosa are stalled in cystic fibrosis bronchial epithelial cells. Eur J Cell Biol. . 2024 Apr 15;103(2):151416. Link.

Mésinèle J, Ruffin M, Guillot L, Boëlle PY, Corvol H. Airway infections as a risk factor for Pseudomonas aeruginosa acquisition and chronic colonisation in children with cystic fibrosis. J Cyst Fibros. 2023 Jul 6:S1569-1993(23)00822-6. Link.

De Luca D, Foligno S, Autilio C, Vivanti A, Vanderkerckhove M, Martinovic J, Raschetti R, Guillot L, Touqui L. Secretory phospholipase A2 expression and activity in preterm clinical chorioamnionitis with fetal involvement. Am J Physiol Lung Cell Mol Physiol. 2022. Link.

Mercier J, Calmel C, Mésinèle J, Sutanto E, Merabtene F, Longchampt E, Sage E, Kicic A, Boëlle PY, Corvol H, Ruffin M and Guillot L. SLC6A14 impacts cystic fibrosis lung disease severity via mTOR and epithelial repair modulation. Front Mol Biosci. 2022. Link.

Mercier et al. Front Mol Biosci. 2022

Latest news

Congratulations Sylvain Brax for the Best oral communication award at the 2024 Cystic Fibrosis meeting "vaincre la mucoviscodose" 

Congratulations Camille Rochard for the Best poster award at the 2023 Cystic Fibrosis meeting "vaincre la mucoviscodose" 


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