Implements various win ratio methodologies for composite endpoints of death and nonfatal events, including the (stratified) proportional win-fractions (PW) regression models (Mao and Wang, 2020 <doi:10.1111/biom.13382>), (stratified) two-sample tests with possibly recurrent nonfatal event, and sample size calculation for standard win ratio test (Mao et al., 2021 <doi:10.1111/biom.13501>).

Contains inferential and graphical routines for comparing two treatment arms in terms of the restricted mean time in favor of treatment (RMT-IF) (Mao, 2021, <doi:10.1111/biom.13570>).

Contains inferential and graphical routines for multi-group analysis of while-alive loss (or event) rate for possibly recurrent nonfatal event in the presence of death.

Implements inferential and graphic procedures for the semiparametric proportional means regression of weighted composite endpoint of recurrent event and death (Mao and Lin, 2016, <doi:10.1093/biostatistics/kxv050>).

Design of group sequential trials, including non-binding futility analysis at multiple time points (Gallo, Mao, and Shih, 2014, <doi:10.1080/10543406.2014.932285>).