The Statistical Analysis of Composite Time-to-Event Outcomes

This half-day short course provides an overview of the novel methods for the analysis of composite time-to-event outcomes.

After this course, you will

  • Understand the challenges of analyzing composite endpoints in accordance with common regulatory guidelines for clinical trials

  • Learn the newly developed hypothesis testing, nonparametric estimation, and semiparametric regression procedures that address those challenges

  • Know how to analyze composite outcomes in real studies using R-packages such as Wcompo, WR, rmt, and WA


  • 2021 ICSA Applied Statistics Symposium [Slides pdf; Full course materials zip]

  • 2021 ASA BIOP Regulatory-Industry Statistics Workshop [Slides pdf; Full course materials zip]

  • 2022 ENAR Spring Meeting, Houston TX [Slides pdf; Full course materials zip]