Publications

Selected papers:

Liu, S., Payne, A.M., Wang, J. et al. Architecture and activation of single-pass transmembrane receptor guanylyl cyclase. Nat Struct Mol Biol 32, 469–478 (2025). 

Liu, S.*, Paknejad, N.*, Zhu, L. et al. Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate. Nat Commun 13, 731 (2022). 

Liu, S., Gonen, T. MicroED structure of the NaK ion channel reveals a Na+ partition process into the selectivity filter. Commun Biol 1, 38 (2018). 

Liu S., Focke P.J., Matulef K., Bian X., Moënne-Loccoz P., Valiyaveetil F.I., Lockless S.W. Ion-binding properties of a K+ channel selectivity filter in different conformations. Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15096-100. 

Huang H.*, Levin E.J.*, Liu S., Bai Y., Lockless S.W., Zhou M. (2014) Structure of a Membrane-Embedded Prenyltransferase Homologous to UBIAD1. PLoS Biol 12(7): e1001911. 

Liu, S., Lockless, S. Equilibrium selectivity alone does not create K+-selective ion conduction in K+ channels. Nat Commun 4, 2746 (2013). 

Liu X., Liu S., Feng Y., Liu J.Z., Chen Y., Pham K., Deng H., Hirschi K.D., Wang X., Cheng N.. Structural insights into the N-terminal GIY-YIG endonuclease activity of Arabidopsis glutaredoxin AtGRXS16 in chloroplasts. Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9565-70. 

Liu S.*, Bian X.*, Lockless S.W.. Preferential binding of K+ ions in the selectivity filter at equilibrium explains high selectivity of K+ channels. J Gen Physiol. 2012 Dec;140(6):671-9.

*co-first author