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Shining lights to explore the secret of life
Research Overview
It is a long-coveted dream for human to gaze upon cells in real time. Microscopy enables us to look at fine details of cells, tissues and animals. With the help of fluorescence probes and reporters, the biomedical research becomes a colorful world. We are using advanced intravital 2-photon (2p) microscopy to visualize physiological or pathological biological processes in live animals. The optical sectioning and penetration powers of 2p imaging enables brain imaging in live animals at fine details. The availability of a variety of fluorescent probes empowers 2p microscopy and opens unlimited possibilities to unfold the secret of life from unprecedented perspectives.
Stroke
Stroke
Laser speckle image of stroked brain
Brain cancers
Brain cancers
Glioblastoma growing in the brain
Neurodegenerative disease
Neurodegenerative disease
Aggregation of alpha-synuclein in cells
About the Lab
The lab is affiliated with the Program of Image Guided Neurointervention in the Department of Diagnostic Radiology and Nuclear Medicine at University of Maryland School of Medicine. We develop imaging methods and biomedical devices to study brain diseases and seek clues for novel therapies.
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