Lee TM (selected publications)

(A). Chlamydomonas reinhardtii High Light Physiology and Oxidative Stress

01. Chang HL, Hsu YT, Kang CY, Lee TM. 2013. Nitric oxide down-regulation of carotenoid synthesis and PSII activity in relation to very high light-induced singlet oxygen production and oxidative stress in Chlamydomonas reinhardtii. Plant and Cell Physiology 54:1296-1315

02. Chang SL, Kang CY, Lee TM. 2013. Hydrogen peroxide production protects Chlamydomonas reinhardtii against light-induced cell death by preventing singlet oxygen accumulation through enhanced carotenoid synthesis. Journal of Plant Physiology 170: 976-986.

03. Chang HL, Tseng YL, Ho KL, Shie SC, Wu PS, Hsu YT, Lee TM. 2014. Reactive oxygen species modulate the differential expression of methionine sulfoxide reductase genes in Chlamydomonas reinhardtii by high light illumination. Physiologia Plantarum 144: 225–237

04. Lin ST, Chiou CW, Chu YL, Hsiao Y, Tseng YF, Chen YC, Chen HJ, Chang HY, Lee TM. 2016. Enhanced ascorbate regeneration via dehydroascorbate reductase confers tolerance to photooxidative stress in Chlamydomonas reinhardtii. Plant Cell Physiology 57:2104-2121

05. Chang HY, Lin ST, Ko TP, Wu SM, Lin TH, Chang YC, Huang KF, Lee TM. 2017. Enzymatic characterization and crystal structure analysis of Chlamydomonas reinhardtii dehydroascorbate reductase and their implications for oxidative stress. Plant Physiology and Biochemistry 120: 144-155

06. Lin TH, Rao MY, Lu HW, Chiou CW, Lin ST, Chao HW, Zheng ZL, Chen HC, Lee TM. 2018. A role for glutathione reductase and glutathione in the tolerance of Chlamydomonas reinhardtii to photo-oxidative stress, Physiologia Plantarum 162: 35-48.

07. Yeh HL, Lin TH, Chen CC, Cheng TX, Chang HY, Lee TM. 2019. Monodehydroascorbate reductase plays a role in the tolerance of Chlamydomonas reinhardtii to photooxidative stress. Plant and Cell Physiology 60: 2167–2179.

08. Kuo EYH, Chang HL, Lin ST, Lee TM* 2020. High Light-Induced Nitric oxide production induces autophagy and cell death in Chlamydomonas reinhardtii. Frontiers in Plant Sciences 11: 772.

09. Kuo EYH, Cai MS, Lee TM. 2020. Ascorbate peroxidase 4 plays a role in the tolerance of Chlamydomonas reinhardtii to photo-oxidative stress. Scientific Reports 10: 13287.

(B). Marine Macroalgal Stress Physiology

01. Lee TM, Chen MH. 1998. Hyposaline effect on polyamine accumulation in Ulva fasciata (Ulvales, Chlorophyta). Botanical Bulletin of Academia Sinica 39: 167-174.

02. Lee TM. 1998. Investigations of some intertidal green macroalgae to hyposaline stress: detrimental role of putrescine under extreme hyposaline condition. Plant Science 138: 1-8.

03. Lee TM.1999. Changes in properties of biosynthetic enzymes in relation to high temperature-induced proline accumulation in Gracilaria tenuistipitata (Gigartinales, Rhodophyta). Phycologia 37: 433-438.

04. Lee TM. 1999. The role of proline dehydrogenase and D1-pyrroline-5-carboxylate dehydrogenase in the regulation of proline homeostasis in Gracilaria tenuistipitata (Gigartinales, Rhodophyta) exposed to high temperature. Phycologia 37: 439-442.

05. Lee TM, Chang YC. 1999. An increase of ornithine d–aminotransferase-mediated proline synthesis in relation to high temperature injury in Gracilaria tenuistipitata (Gigartinales, Rhodophyta). Journal of Phycology 35: 84-88.

06. Chang WC, Chen MH, Lee TM. 1999. 2,3,5-Triphenyltetrazolium reduction in the viability assay of Ulva fasciata (Chlorophyta) in response to salinity stress. Botanical Bulletin of Academia Sinica 40: 207-212.

07. Lee TM, Chang YC, Lin YH. 1999. Differences in short-term physiological responses between winter- and summer-grown Gracialria tenuistipitata (Gigartinales, Rhodophyta) to varying temperature. Botanical Bulletin of Academia Sinica 40: 93-100.

08. Chang YC, Lee TM. 1999. High temperature-induced free proline accumulation in Gracilaria tenuistipitata (Rhodophyta). Botanical Bulletin of Academia Sinica 40:289-294.

09. Lee TM. 1999. Phosphate starvation induction of acid phosphatase in Ulva fasciata (Ulvales, Chlorophyta). Botanical Bulletin of Academia Sinica 41: 19-25.

10. Lee TM, Liu CH. 1999. Regulation of NaCl-induced proline accumulation by calmodulin via a modification of proline dehydrogenase activity in Ulva fasciata (Chlorophyta). Australian Journal of Plant Physiology 26: 595-600.

11. Lee TM, Tsai CC, Shih MC. 1999. Induction of phosphorus deficiency and phosphatase activity by salinity (NaCl) stress in Gracilaria tenuistipitata (Gigartinales, Rhodophyta). Phycologia 38: 428-433.

12. Lee TM, Liu CH. 1999. Correlation of decreased calcium contents with proline accumulation in the marine green macroalga Ulva fasciata exposed to elevated NaCl contents in seawater. Journal of Experimental Botany 50:1855-1859.

13. Liu CH, Shih MC, Lee TM. 2000. Free proline levels in Ulva (Chlorophyta) in response to hypersalinity: elevated NaCl in seawater versus concentrated seawater. Journal of Phycology 35: 1-2.

14. Lee TM. 2004. Induction of acid phosphatase activity by phosphorus deficiency in Gracilaria coronopifolia (Gigartinales, Rhodophyta). Phycologia 43: 493-500.

15. Hwang RL, Tsai CC, Lee TM. 2004. Assessment of temperature and nutrient limitation on seasonal dynamics among species of Sargassum from a coral reef in southern Taiwan. Journal of Phycology 40: 463-473.

16. Tsai CC, Wong SL, Chang JS, Hwang RL, Dai CF, Yu YC, Shyu YT, Sheu F, Lee TM. 2004. Macroalgal assemblage structure on a coral reef of Nanwan Bay in southern Taiwan. Botanica Marina 47: 439-453.

17. Tsai CC, Chang JS, Sheu F, Shyu YT, Yu YC Amanda, Wong SL, Dai CF, Lee TM. 2005. Seasonal growth dynamics of Laurencia papillosa and Gracilaria coronopifolia from a highly eutrophic reef in southern Taiwan: temperature limitation and nutrient availability. Journal of Experimental and Marine Biology and Ecology 315: 49-69.

18. Lee TM, Huang YL, Chen MH. 2005. Copper induction of phosphorus deficiency in Ulva fasciata (Ulvales, Chlorophyta). Phycologia 44: 620-628.

19. Lee TM, Tsai PF, Shyu YT, Sheu F. 2005. The effects of phosphite on phosphate starvation responses of Ulva lactuca (Ulvales, Chlorophyta). Journal of Phycology 41: 975-982.

20. Shiu CT, Lee TM. 2005. Ultraviolet-B-induced oxidative stress and responses of the ascorbate–glutathione cycle in a marine macroalga Ulva fasciata. Journal of Experimental Botany 56: 2851-2865.

21. Lu IF, Sung MS, Lee TM. 2006. Salinity stress and hydrogen peroxide regulation of antioxidant defense system in Ulva fasciata. Marine Biology 150: 1-15.

22. Chung IC, Su SW, Wu JY, Hwang RL, Wu TM, Lin SH, Chen CS, Lee TM. 2007. Nutrient and salinity as primary factors influencing temporal dynamics of macroalgal abundance and assemblage structure on a reef of Du-Lang Bay in southeastern Taiwan. Botanical Studies 48: 419-433.

23. Wu TM, Lee TM. 2008. Regulation of activity and gene expression of antioxidant enzymes in Ulva fasciata Delile (Ulvales, Chlorophyta) in responses to excess copper. Phycologia 47: 346-360.

24. Lee TM, Wu JY. 2008. Roles of temperature and precipitation on geographic difference of intertidal macroalgal abundance and assemblage structure along Taiwan’s coast. Kuroshio Science 2: 47-58.

25. Wu TM, Hsu YT, Lee TM. 2009. Effects of cadmium on the regulation of antioxidant enzyme activity and gene expression and antioxidant in a marine macroalga Ulva fasciata. Botanical Studies 50: 25-34.

26. Sung MS, Hsu YT, Hsu YT, Wu TM, Lee TM. 2009. Hypersalinity and hydrogen peroxide upregulation of gene expression of antioxidant enzymes in Ulva fasciata against oxidative stress. Marine Biotechnology 11: 199-209.

27. Lee TM, Shiu CT. 2009. Implications of mycosporine-like amino acid and antioxidant defenses in UVB radiation tolerance for the algae species Ptercladiella capillacea and Gelidium amansi. Marine Environmental Research 67: 8-16.

28. Wu TM, Hsu YT, Sung MS, Hsu YT, Lee TM. 2009. Expression of genes involved in redox homeostasis and antioxidant defense in a marine macroalga Ulva fasciata by excess copper. Aquatic Toxicity 94: 175-185.

29. Hsu YT, Lee TM. 2010. Photosynthetic electron transport mediates the light-controlled up-regulation of expression of methionine sulfoxide reductase A and B from marine macroalga Ulva fasciata. Journal of Phycology 46:112-122.

30. Sung MS, Hsu YT, Ho KL, Lee TM. 2011. Implications of the up-regulation of genes encoding protein degradation enzymes and heat shock protein 90 for intertidal green macroalga Ulva fasciata against hypersalinity-induced protein oxidation. Marine Biotechnology 13: 684-694.

31. Sung MS, Chow TC, Lee TM. 2011. Polyamine acclimation alleviates hypersalinity-induced oxidative stress in a marine macroalga Ulva fasciata by modulation of antioxidative enzyme gene expression. Journal of Phycology 47: 538-547.

32. Hsu YT, Lee TM. 2012. Nitric oxide up-regulates the expression of methionine sulfoxide reductase genes in the intertidal macroalga Ulva fasciata for high light acclimation. Plant and Cell Physiology 53: 445-456.

33. Hsu YT, Lee TM. 2012. Modulation of gene expression of carotene biosynthesis-related protein by photosynthetic electron transport for the acclimation of intertidal macroalga Ulva fasciata to hypersalinity and excess light. Physiologia Plantarum 144: 225–237.

34. Li LC, Hsu YT, Chang HL, Wu TM, Sung MS, Cho CL, Lee TM. 2013. Effect of polyamines on the expression polyamines of protein disulfide isomerase and its implication against hypersalintity stress in marine alga Ulva fasciata Delile. Journal of Phycology 49: 1181-1191.

35. Su SY, Lee TM, Mok HK, Chio EH. 2016. Insecticidal activity and insect repellency of four species of sea lily (Comatulida: Comatulidae) from Taiwan. Journal of Insect Science 16: 1–5.

36. Yuan SP, Tang XX, Yu Q, Yu Z, Lee TM, Zhou B. 2018. Effect of acute UVB radiation on the antioxidant system in Sargassum glaucescens. Oceanologia et Limnologia Sinica 49: 821-828.

(C). Algal Bio-Energy and High-Value Compound Production

01. Shen CT, Chen PY, Wu JJ, Lee TM, Hsu SL, Chang CMJ, Young CC, Shieh CJ. 2011. Purification of algal anti-tyrosinase zeaxanthin from Nannochloropsis oculata using supercritical anti-solvent precipitation. Journal of Supercritical Fluids 55: 955-962.

02. Cho YC, Cheng JH, Hsu SL, Hong SE, Lee TM, Chang CMJ. 2011. Supercritical carbon dioxide anti-solvent precipitation of anti-oxidative zeaxanthin highly recovered by elution chromatography from Nannochloropsis oculata. Separation and Purification Technology 78: 274-280.

03. Su HY, Lee TM, Huang YL, Chou SH, Wang JB, Lin LF, Chow TJ. 2011. Increased cellulose production by heterologous expression of cellulose synthase genes in a filamentous heterocystous cyanobacterium with a modification in photosynthesis performance and growth ability. Botanical Studies 52: 265-275.

04. Chen PY, Shen CT, Liau BC, Lee TM, Wu TM, Shieh CJ, Chang CMJ. 2011. Demonstration of continuous supercritical carbon dioxide anti-solvent purification and classification of nano/micro sized precipitates of algal zeaxanthin from Nannochloropsis oculata. Journal of the Taiwan Institute of Chemical Engineers 42: 598-603.

05. Show KY, Lee DJ, Tay JH, Lee TM, Chang JS. 2015. Microalgal drying and cell disruption - Recent advances. Bioresource Technology 184: 258-266.

06. Chow TJ, Su HY, Tsai TY, Chou HH, Lee TM, Chang JS. 2015. Using recombinant cyanobacterium (Synechococcus elongatus) with increased carbohydrate productivity as feedstock for bioethanol production via separate hydrolysis and fermentation process. Bioresource Technology 184: 33-41.

07. Yeh TJ, Tseng YF, Chen YC, Hsiao Y, Lee PC, Chen TJ, Chen CY, Kao CY, Chang JS, Chen JC, Lee TM. 2017. Transcriptome and physiological analysis of a lutein-producing alga Desmodesmus sp. reveals the molecular mechanisms for high lutein productivity. Algal Research 21: 103-119.

08. Lee TM, Tseng YF, Cheng CL, Chen YC, Lin CS, HYSu,Chow TJ, Chen CY, Chang JS. 2017. Characterization of a heat‑tolerant Chlorella sp. GD mutant with enhanced photosynthetic CO2 fixation efficiency and its implication as lactic acid fermentation feedstock, Biotechnol Biofuels 10: 214.

09. Lam TP, Lee TM, Chen CY, Chang JS. 2018. Strategies to control biological contaminants during microalgal cultivation in open ponds. Bioresource Technology 252: 180–187

10. Chou HH, Su HY, Song XD, Chow TJ, Chen CY, Chang JS, Lee TM. 2019. Isolation and characterization of Chlorella sp. mutants with enhanced thermo- and CO2 tolerances for CO2 sequestration and utilization of flue gases. Biotechnology for Biofuels 12: 251

11. Chou HH, Su HY, Chow TJ, Lee TM, Chenge WH, Chang JS, Chen HJ. 2021. Engineering cyanobacteria with enhanced growth in simulated flue gases for high-yield bioethanol production. Biochemical Engineering Journal 165: 107823.

(D). Rice and Higher Plant Stress Physiology

01.李澤民, 朱鈞. 1988. 植物生長調節物質與作物生產. 二、在水稻生產之應用. 科學農業 36: 115-123.

02. Chu C, Lee TM. 1989 The relationship between ethylene biosynthesis and chilling tolerance in seedlings of rice (Oryza sativa L.). Botanical Bulletin of Academia Sinica 30: 263-273.*

03. Chu C, Lee TM. 1991. Hormone regulatory system in chilling tolerance of plants. Chinese Agronomy Journal 1: 207-224.

04. Lee TM, Lur HS, Chu C. 1991. Involvement of abscisic acid in chilling tolernce of rice (Oryza sativa L.) seedlings. Plant Physiology 96: S-1113.

05. Lee TM, Lur HS, Chu C. 1991. Role of proline content in chilling tolerance of rice (Oryza sativa L.) seedlings. Plant Physiology 96: S-1111.

06. Chu C, Lee TM. 1992. Regulation of chilling toleracne in rice seedlings by plant hormone. Korean Journal of Crop Science 37: 288-298.

07. Chan MT, Lee TM, Chang HS. 1992. Agrobacterium-mediated transformation in rice (Oryza sativa L.) roots. Plant Cell Physiology 33: 577-583.

08. Lee TM, Chu C. 1992. Ethylene-induced polyamine accumulation in rice (Oryza sativa L.) coleoptiles. Plant Physiology 100: 238-245.

09. Lee TM, Lur HS, Chu C. 1992. Changes of abscisic acid contents in chilled rice (Oryza sativa L.) seedlings. Plant Physiology 99: S-831.

10. Lee TM, Shieh YJ. 1993. o-Hydroxyphenylacetic acid-enhanced rice coleoptile elongation. Plant Science 95: 49-54.

11. Lee TM, Lur HS, Chu C. 1993. Roles of abscisic acid in chilling tolerance of rice (Oryza sativa L.) seedlings. I. Endogenous abscisic acid levels. Plant, Cell and Environment 16: 481-490.*

12. Liu MS, Lee TM, Lin YH. 1994. New discoveries concerning rice trypsin inhibitors. Botanical Bulletin of Academia Sinica 35: 211-216.

13. Lee TM, Lur HS, Shieh YJ, Chu C. 1994. Levels of abscisic acid in anoxia- or ethylene-treated rice (Oryza sativa L.) seedlings. Plant Science 95: 125-131.

14. Lee TM, Lin YH. 1995. Changes in soluble and cell wall-bound peroxidase activities with growth in anoxia-treated rice (Oryza sativa L.) coleoptiles and roots. Plant Science 106: 1-7.

15. Lee TM, Lur HS, Chu C. 1995. Abscisic acid and putrescine accumulation in chilling-tolerant rice cultivars. Crop Science 35: 502-508.

16. Lee TM, Lin YH. 1995. Trypsin inhibitor and trypsin-like protease activity in air- or submergence-grown rice (Oryza sativa L.) coleoptiles. Plant Science 106: 43-54.

17. Lee TM, Lin YH. 1996. Peroxidase activity in relation to ethylene-induced rice (Oryza sativa L.) coleoptile elongation. Botanica Bulletin of Academia Sinica 37: 239-245.

18. Lee TM, Lur HS, Chu C, Lin YH. 1996. Physiological and biochemical changes in relation to methyl jasmonate-induced chilling tolerance of rice (Oryza sativa L.) seedlings. Plant, Cell and Environment 19: 65-74.

19. Lee TM, Shieh YJ, Chou CH. 1996. Role of putrescine in enhancing shoot elongation in Scirpus mucronatus under submergence. Physiologia Plantarum 96: 419-424.

20. Lee TM, Shieh YJ, Chou CH. 1996. Abscisic acid inhibits shoot elongation of Scirpus mucronatus. Physiologia Plantarum 97: 1-7.

21. Lee TM, Lin YH. 1996. Opposite effects of fusicoccin and IAA on putrescine synthesis of rice coleoptiles. Physiologia Plantarum 97: 63-68.

22. Lee TM, Lin YH. 1996. Peroxidase activity in ethylene-, ABA-, or MeJA-treated rice (Oryza sativa L.) roots. Botanical Bulletin of Academia Sinica 37: 201-207.

23. Lee TM. 1997. Polyamine regulation of growth and chilling tolerance of rice (Oryza sativa L.) roots cultured in vitro. Plant Science 122: 111-117.

24. Lee TM, Lur HS, Chu C. 1997. Role of abscisic acid in chilling tolerance of rice (Oryza sativa L.) seedlings. II. Modulation of free polyamine levels. Plant Science 126: 1-10.*

25. Chang ML, Liao LJ, Lin JH, Liu ZH, Hsu YT, Lee TM. 2012. Modulation of antioxidant defense system and NADPH oxidase in Pluchea indica leaves by water deficit stress. Botanical Studies 53: 45-54.

26. Hsu YT, Lee TM. 2018. Abscisic acid-dependent nitric oxide pathway and abscisic acid-independent nitric oxide routes differently modulate NaCl stress induction of the gene expression of methionine sulfoxide reductase A and B in rice roots Journal of Plant Physiology 231: 374–382.