K. Kito, M. Hayashi, T. Kaneko, “Electrophysiological Analysis of Hyperkalemic Cardiomyocytes using a Multielectrode Array System”, Biophysics and Physicobiology, 21, e210026 (2024).
S. Arai, K. Lloyd , T. Takahashi, K. Mammoto, T. Miyazawa, K. Tamura, T. Kaneko, K. Ishida, Y. Moriyama, T. Mitsui, “Dynamic Properties of Heart Fragments from Different Regions and Their Synchronization”, Bioengineering, 7(3), 81 (2020).
Y. Asahi, T. Hamada, A. Hattori, K. Matsuura, M. Odaka, F. Nomura, T. Kaneko, Y. Abe, K. Takasuna, A. Sanbuissho, K. Yasuda, “On-chip Spatiotemporal Electrophysiological Analysis of Human Stem Cell Derived Cardiomyocytes enables Quantitative Assessment of Proarrhythmia in Drug Development,” Sci. Rep., 8: 14536 (2018).
T. Kaneko*, H. Toriumi, J. Shimada, F. Nomura, “Extracellular field potential recording of single cardiomyocytes in agarose microchambers using microelectrode array,” Jpn. J. Appl. Phys., 57: 03EB03 (2018)
K. Fujii, F. Nomura, T. Kaneko, “Dependences of the geometrical parameters of cell community on stimulation voltage and frequency in chick embryonic cardiomyocytes,” Jpn. J. Appl. Phys., 57: 03EB04 (2018)
F. López-Redondo, J. Kurokawa, F. Nomura, T. Kaneko, T. Hamada, T. Furukawa, K. Yasuda, “A distribution analysis of action potential parameters obtained from patch-clamped human stem cell-derived cardiomyocytes,” J. Pharmacol. Sci., 131: 141-145 (2016)
T. Kaneko, F. Nomura, T. Hamada, Y. Abe, H. Takamori, T. Sakakura, K. Takasuna, A. Sanbuissho, J. Hyllner, P. Sartipy, K. Yasuda, “On-chip in vitro cell-network pre-clinical cardiac toxicity using spatiotemporal human cardiomyocyte measurement on a chip,” Scientific Reports, 4: 4670 (2014)
H. Terazono, A. Hattori, H. Kim, H. Takei, F. Nomura, T. Kaneko, K. Yasuda, “Temperature-Shift Speed Dependence of Nonspecific Amplification of Polymerase Chain Reaction Examined by 1480nm Photothermal Transition Speed Controllable High-Speed Polymerase Chain Reaction System,” Jpn. J. Appl. Phys., 52: 06GK02 (2013)
T. Hamada, T. Kaneko, F. Nomura, K. Yasuda, “Physiological Sample Uniformity and Time–Course Stability in Lined-Up Structure of Human Cardiomyocyte Network for In vitro Predictive Drug-Induced Cardiotoxicity,” Jpn. J. Appl. Phys., 52: 06GK05 (2013)
T. Kaneko, E. Takizawa, F. Nomura, T. Hamada, A. Hattori, K. Yasuda, “On-Chip Single-Cell-Shape Control Technology for Understanding Contractile Motion of Cardiomyocytes Measured Using Optical Image Analysis System,” Jpn. J. Appl. Phys., 52: 06GK06 (2013)
F. Nomura, T. Kaneko, T. Hamada, A. Hattori, K. Yasuda, “Advanced Ring-Shaped Microelectrode Assay Combined with Small Rectangular Electrode for Quasi-In vivo Measurement of Cell-to-Cell Conductance in Cardiomyocyte Network,” Jpn. J. Appl. Phys., 52: 06GK07 (2013)
C. A. Brunello, V. Jokinen, P. Sakha, H. Terazono, F. Nomura, T. Kaneko, S. E. Lauri, S. Franssila, C. Rivera1, K. Yasuda, H. J. Huttunen, “Microtechnologies to fuel neurobiological research with nanometer precision,” J. Nanobiotechnology, 11: 11 (2013)
H. Hamada, F. Nomura, T. Kaneko, K. Yasuda, M. Okamoto, “Exploring the implicit interlayer regulatory mechanism between cells and tissue: Stochastic mathematical analyses of the spontaneous ordering in beating synchronization,” Biosystems, 111:208-215 (2013)
K. Yasuda, A. Hattori, H. Kim, H. Terazono, M. Hayashi, H. Takei, T. Kaneko, F. Nomura, “Non-Destructive On-Chip Imaging Flow Cell Sorting System for Constructive On-Chip Cellomics,” Microfluidics and Nanofluidics, DOI 10.1007/s10404-012-1112-6, (2013)
H. Hamada, F. Nomura, T. Kaneko, K. Yasuda, M. Okamoto, "Exploring the implicit interlayer regulatory mechanism between cells and tissue: stochastic mathematical analyses of the spontaneous ordering in beating synchronization," Biosystems, Vol. 111, No. 3, pp. 208-215 (2013)
K. Yasuda, A. Hattori, H Kim, H. Terazono, M. Hayashi, H. Takei, T. Kaneko, F. Nomura, "Non-Destructive On-Chip Imaging Flow Cell Sorting System for Constructive On-Chip Cellomics," Microfluidics and Nanofluidics, DOI10.1007/s10404-012-1112-6 (2012)
H. Terazono, H. Kim, M. Hayashi, A. Hattori, F. Nomura, T. Kaneko, K. Yasuda, "A Non-Destructive Culturing and Cell Sorting Method for Cardiomyocytes and Neurons Using a Double Alginate Layer," PLoS ONE, 7: e42485 (2012)
T. Kaneko, F. Nomura, A. Hattori, K. Yasuda, "Improvement of Electrical Stimulation Protocol for Simultaneous Measurement of Extracellular Potential with On-Chip Multi-Electrode Array System," Jpn. J. Appl. Phys., 51: 06FK02 (2012)
T. Hamada, F. Nomura, T. Kaneko, K. Yasuda, "Importance of Thickness in Human Cardiomyocyte Network for Effective Electrophysiological Stimulation Using On-Chip Extracellular Microelectrodes," Jpn. J. Appl. Phys., 51: 06FK03 (2012)
F. Nomura, T. Kaneko, T. Hamada, A. Hattori, K. Yasuda, "Quantitative Evaluation of Closed-Loop-Shaped Cardiomyocyte Network by Using Ring-Shaped Electrode," Jpn. J. Appl. Phys., 51: 06FK06 (2012)
F. Nomura, T. Kaneko, A. Hattori, K. Yasuda, “Label-free shape-based selection of cardiomyocytes with on-chip imaging cell sorting system,” Journal of Bioprocessing & Biotechniques, S3-003: 1-6 (2011)
F. Nomura, T. Kaneko, A. Hattori, K. Yasuda, “On-chip constructive cell-network study (II): On-chip quasi-in vivo cardiac toxicity assay for ventricular tachycardia/fibrillation measurement using ring-shaped closed circuit microelectrode with lined-up cardiomyocyte cell network,” J. Nanobiotechnology, 9: 39 (2011)
T. Kaneko, F. Nomura, K. Yasuda, “Orientation and community size dependence of pulsatile electrical field stimulation on lined-up cardiomyocytes and rod-shaped single cardiomyocytes,” Jpn. J. Appl. Phys., 50: 080220 (2011)
T. Kaneko, F. Nomura, K. Yasuda, “Quasi-in vivo heart electrocardiogram measurement of ST period using convolution of cell network extracellular field potential propagation in lined-up cardiomyocyte cell-network circuit,” Jpn. J. Appl. Phys., 50: 070213 (2011)
T. Kaneko, F. Nomura, K. Yasuda, “On-chip Constructive Cell-Network Study (I): Contribution of cardiac fibroblasts to cardiomyocyte beating synchronization and community effect,” J. Nanobiotechnology, 9: 21 (2011)
.
M. Hayashi, A. Hattori, H. Kim, H. Terazono, T. Kaneko, K. Yasuda, “Fully Automated On-Chip Imaging Flow Cytometry System with Disposable Contamination-Free Plastic Re-Cultivation Chip,” Int. J. Mol. Sci., 12, 3618-3634 (2011)
A. Hattori, T. Kaneko, K. Yasuda, “Improvement of Particle Alignment Control and Precise Image Acquisition for On-Chip High-Speed Imaging Cell Sorter,” Jpn. J. Appl. Phys., 50: 06GL06 (2011)
M. Hayashi, T. Kaneko, K. Yasuda, “Continuous Concentration and Separation of Microparticles Using Dielectrophoretic Force in a V-Shaped Electrode Array,” Jpn. J. Appl. Phys., 50: 06GL03 (2011)
H. Terazono, M. Hayashi, H. Kim, A. Hattori, T. Kaneko, K. Yasuda, “Image-Based Identification of Single Neurons for Noninvasive Imaging Purification,” Jpn. J. Appl. Phys., 50: 06GL07 (2011)
K. Yasuda, T. Kaneko, F. Nomura, “On-Chip Pre-Clinical Cardiac Toxicity: Testing Compounds Beyond hERG And QT Using hES/hiPS Cardiomyocyte Re-Entry Cell Network Model On a Chip,” Proceeding of The 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, pp. 716-718 (2010)
K. Yasuda, T. Kaneko, F. Nomura, “On-Chip Cellomics for Cardiotoxity: Cell Network Model For Re-Construction of Higher Complexity of Organs,” The Open Conference Proceedings Journal, Vol. 1, pp. 168-177 (2010)
T. Tanaka, S. Tohyama, M. Murata, F. Nomura, T. Kaneko, H. Chen, F. Hattori, T. Egashira, T. Seki, Y. Ohno, U. Koshimizu, S. Yuasa, S. Ogawa, S. Yamanaka, K. Yasuda, K. Fukuda, “In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes,” Biochem. Biophys. Res. Commun., Vol. 385, pp. 497-502 (2009)
T. Kaneko, K. Kojima, K. Yasuda, “An on-chip cardiomyocyte cell network assay for stable drug screening regarding community effect of cell network size,” The Analyst, Vol. 132, (9), pp. 892-898 (2007)
T. Kaneko, K. Kojima, K. Yasuda, “Dependence of the community effect of cultured cardiomyocytes on the cell network pattern,” Biochem. Biophys. Res. Commun., Vol. 356 (2), pp. 494-498 (2007)
K. Kojima, T. Kaneko, and K. Yasuda, “Role of the community effect of cardiomyocyte in the entrainment and reestablishment of stable beating rhythms,” Biochemical and Biophysical Research Communications, Vol. 351 (1), pp. 209-215 (2006)
S. Iwanaga, T. Kaneko, K. Fujita, N. Smith, O. Nakamura, T. Takamatsu, S. Kawata, “Location-Dependent Photogeneration of Calcium Waves in HeLa Cells,” Cell Biochem. Biophys., Vol. 45, Issue 2, pp. 167-176 (2006)
T. Kaneko, K. Kojima, K. Yasuda, “Using agarose microchamber system, measurements of community effects of the cardiomyocytes and the heterogeneous cell types,” Proceedings of The 6th International Conference on Intelligent Materials and Systems, pp. 183-186 (2005)
K. Kojima, T. Kaneko, K. Yasuda, “Stability of beating frequency in cardiac myocytes by their community effect measured by agarose microchamber chip,” J. Nanobiotechnology, Vol. 3, 4 (2005)
K. Kojima, T. Kaneko, K. Yasuda, “A novel method of cultivating cardiac myocytes in agarose microchamber chips for studying cell synchronization,” J. Nanobiotechnology, Vol. 2, 9 (2004)
Y. Sugio, K. Kojima, H. Moriguchi, K. Takahashi, T. Kaneko, K. Yasuda, “An agar-based on-chip neural-cell cultivation system for stepwise control of network pattern generation during cultivation,” Sensors & Actuators B: Chemical Vol. 99, Issue 1, pp. 156-162 (2004)
K. Kojima, H. Moriguchi, A. Hattori, T. Kaneko, K. Yasuda, “Two-dimensional Network Formation of Cardiac Myocytes in Agar Microculture Chip with 1480-nm Infrared Laser Photo-thermal Etching,” Lab Chip Vol. 3 (4), pp. 292-296 (2003)
K. Kojima, K. Takahashi, T. Kaneko, K. Yasuda, “Flexible control of electrode pattern on cultivation chamber during cultivation of cells using non-destructive optical etching,” Jpn. J. Appl. Phys. Vol. 42 (8A), pp. L980-L982 (2003)
S. Iwanaga, N. Smith, K. Fujita, T. Kaneko, O. Nakamura, S. Kawata, M. Oyamada, T. Takamatsu, "Stimulation of living cells by using femtosecond near-infrared laser pulses," Proceedings of SPIE, Vol. 4978, pp.122-128 (2003)
H. Moriguchi, K. Takahashi, T. Kaneko, K. Yasuda, “On-chip agarose-microchamber (AMC) array cell-cultivation system for topographical control of neural network,” Proceedings of Micro Total Analysis System Symposium 2002, Vol. 1, pp.13-15 (2002)
M. Kobayashi, K. Fujita, T. Kaneko, T. Takamatsu, O. Nakamura, S. Kawata, “Second-harmonic-generation microscope with a microlens array scanner,” Opt. Lett., Vol. 27, pp. 1324-1326 (2002)
N. Smith, K. Fujita, T. Kaneko, K. Kato, O. Nakamura, T. Takamatsu, S. Kawata, "Generation of calcium waves in living cells by pulsed laser-induced photodisruption, " Applied Physics Letters, Vol. 79, pp. 1208-1210 (2001).
T. Kaneko, H. Tanaka, M. Oyamada, S. Kawata, T. Takamatsu, "Three distinct types of Ca2+ waves in Langendorff-perfused rat heart revealed by real-time confocal microscopy," Circulation Research, Vol. 86 (10), pp. 1093-1099 (2000).
K. Fujita, O. Nakamura, T. Kaneko, M. Oyamada, T. Takamatsu, S. Kawata, "Confocal multipoint multiphoton excitation microscope with microlens and pinhole arrays," Optics Communications, Vol. 174, pp. 7-12 (2000).
K. Fujita, T. Kaneko, O. Nakamura, M. Oyamada, T. Takamatsu, S. Kawata, "Real-time Ca ion wave imaging in living rat-cardiac muscle cells by a confocal multiphoton microscope with a microlens-pinhole array scanner," Proc. of SPIE, Vol. 3921, No.15, pp. 305-312 (2000).
K. Fujita, O. Nakamura, T. Kaneko, M. Oyamada, T. Takamatsu, S. Kawata, "Real-time imaging of two-photon induced fluorescence with a microlens-array scanner and a regenerative amplifier," Journal of Microscopy, Vol. 194, Part 2/3, pp. 528-531 (1999).
K. Fujita, T. Kaneko, O. Nakamura, M. Oyamada, T. Takamatsu, S. Kawata, "Real-time confocal two-photon fluorescence microscope using a rotating microlens array," Proc. SPIE, Vol. 3740, pp. 390-393 (1999).
T. Kaneko, T. J. Itoh, H. Hotani, "Morphological transformation of liposomes caused by assembly of encapsulated tubulin and determination of shape by microtubule associated proteins (MAPs)," J. Mol. Biol. Vol. 284 (5), pp. 1671-1681 (1998)
安田賢二、金子智行、野村典正、服部明弘 「再生医療製品の許認可と組織工学の新しい試み」シーエムシー出版, pp. 135-145(2012)総ページ数209
Tomoyuki Kaneko, Kensuke Kojima, and Kenji Yasuda, “Study of community effects of the cardiomyocytes with an agarose microchamber system,” In “Frontiers in Life Sciences,” Edited by Makoto Fujiwara, Shoichi Ishiura, and Naoki Sato, Research Signpost, pp.27-38 (2006) ISBN: 81-308-0071-3
S. Kawata, O. Nakamura, T. Kaneko, M. Hashimoto, K. Goto, N. I. Smith, T. Sugiura, I. Fujimasa, H. Matsumoto, “Biological Imaging and Sensing from Basic Techniques to Clinical Application,” In “Biological Imaging and Sensing,” Edited by T. Furukawa, Springer-Verlag Berlin Heidelberg, pp. 1-67 (2004)
田中秀央、金子智行、辻井秀治、小山田正人、高松哲郎
心筋の構造と代謝-2000-
ラット摘出灌流心における心筋細胞内カルシウムの動態ｰリアルタイム共焦点レーザ顕微鏡による空間的時間的解析
pp. 177-182 2001年 六方出版社
M. Oyamada, Y. Oyamada, T. Kaneko, and T. Takamatsu, "Regulation of Gap Junction Protein (Connexin) Genes and Function in Differentiating ES Cells," In "Methods in Molecular Biology, Vol. 185: Embryonic Stem Cells: Methods and Protocols", Edited by K. Turksen, Humana Press Inc., Totowa, NJ, pp. 63-69 (2001)
金子智行、田中秀央、小山田正人、高松哲郎
バイオイメージングの最先端
第5章 細胞の機能を探るバイオイメージング技術
灌流心におけるin situ カルシウム・イメージング
pp. 188-192 発行1999年12月27日 先端医療技術研究所 ISBN: 4-925089-05-6