Publications

From 2010-

Nagao K, Takahashi T, Yokoyama R. (2025) Effect of environmental conditions on seed germination and seedling growth in Cuscuta campestris. Plant Growth Regul.  https://doi.org/10.1007/s10725-025-01331-5

Mase H, Sumiura A, Yoshitake Y, Kohchi T, Takahashi T, Motose H. (2025) Involvement of a NIMA-related kinase in cell division in a liverwort Marchantia polymorpha. Plant Cell Physiol. pcaf021. https://doi.org/10.1093/pcp/pcaf021

Mutsuda K, Nishii Y, Toyoshima T, Fukushima H, Motose H, Takahashi T. (2025) Specific enhancement of the translation of thermospermine-responsive uORF-containing mRNAs by ribosomal mutations in Arabidopsis thaliana. Plant Signal. Behav. 20(1). https://doi.org/10.1080/15592324.2025.2480231

Nagata K, Maekawa I, Takahashi T, Abe M. (2024) ATML1 and PDF2 regulate cuticle formation and protect the plant body from environmental stresses in Arabidopsis thaliana seedlings. J. Plant Res. https://doi.org/10.1007/s10265-024-01604-6

Furumoto T, Yamaoka S, Kohchi T, Motose H, Takahashi T. (2024) Thermospermine is an evolutionarily ancestral phytohormone required for organ development and stress responses in Marchantia Polymorpha. Plant Cell Physiol. 65: 460-471

Okamoto T, Motose H. Takahashi T (2023) Microtubule-associated proteins WDL5 and WDL6 play a critical role in pollen tube growth in Arabidopsis thaliana. Plant Signal. Behav. doi/full/10.1080/15592324.2023.2281159

Nishii Y, Koyama D, Fukushima H, Takahashi T (2023) Suppression of the dwarf phenotype of an Arabidopsis mutant defective in thermospermine biosynthesis by a synonymous codon change in the SAC51 uORF. Mol Genet Genomics. doi: 10.1007/s00438-023-02076-4

西井裕一・高橋卓 (2023) ”シロイヌナズナの変異体解析から判明したサーモスペルミンの作用機構” 『アグリバイオ』 ８月号臨時増刊号 pp. 49-52

Matsuo H, Fukushima H, Kurokawa S, Kawano E, Okamoto T, Motose H, Takahashi T (2022) Loss of function of an Arabidopsis homolog of JMJD6, suppresses the dwarf phenotype of acl5, a mutant defective in thermospermine biosynthesis. FEBS Lett. 596: 3005-3014

Mase H, Nakagami H, Okamoto T, Takahashi T, Motose H (2022) Establishment and application of novel culture methods in Marchantia polymorpha: persistent tip growth is required for substrate penetration by rhizoids. Commun. Integr. Biol. 6;15(1): 164-167

Yariuchi Y, Okamoto T, Noutoshi Y, Takahashi T (2021) Responses of polyamine-metabolic genes to polyamines and plant stress hormones in Arabidopsis seedlings. Cells 10: 3283

高橋卓・本瀬宏康 (2021) ”植物ポリアミンの代謝と機能” 『化学と生物』 日本農芸化学会会誌  6月号 pp. 290-297

Katayose A, Kanda A, Kubo Y, Takahashi T, Motose H (2021) Distinct functions of ethylene and ACC in the basal land plant Marchantia polymorpha. Plant Cell Physiol. pcab042

Nagata K, Ishikawa T, Kawai-Yamada M, Takahashi T, Abe M (2021) Ceramides mediate positional signals in Arabidopsis thaliana protoderm differentiation. Development 148: dev194969

Okamoto T, Takatani S, Motose H, Iida H, Takahashi T (2021) The root growth reduction in response to mechanical stress involves ethylene-mediated microtubule reorganization and transmembrane receptor-mediated signal transduction in Arabidopsis. Plant Cell Rep. https://doi.org/10.1007/s00299-020-02653-6

Tanaka T, Nishii Y, Matsuo H, Takahashi T (2020) Easy-to-use indel markers for genetic mapping between Col-0 and Ler-0 accessions of Arabidopsis thaliana. Plants  9: 779

Takahashi T (2020) Editorial: Plant polyamines. Plants 9: 511

Takamura H, Motose H, Otsu T, Shinohara S, Kouno R, Kadota I, Takahashi T (2020) Chemical synthesis and biological effect on xylem formation of xylemin and Its analogues. Eur. J. Org. Chem. 10: 1002/ejoc.202000322

Takatani S, Verger S, Okamoto T, Takahashi T, Hamant O, Motose H (2020) Microtubule response to tensile stress is curbed by NEK6 to buffer growth variation in the Arabidopsis hypocotyl. Curr. Biol. 30: 1-13

Okamoto T, Takahashi T (2019) Ethylene signaling plays a pivotal role in mechanical-stress-induced root-growth cessation in Arabidopsis thaliana. Plant Signal. Behav. 14: 1669417

Miyamoto M, Shimao S, Tong W, Motose H, Takahashi T (2019)  Effect of thermospermine on the growth and expression of polyamine-related genes in rice seedlings. Plants 8: E269.

Shinohara S, Okamoto T, Motose H, Takahashi T (2019)  Salt hypersensitivity is associated with excessive xylem development in a thermospermine-deficient mutant of Arabidopsis thaliana. Plant J. 100: 374-383 

Ishitsuka S, Yamamoto M, Miyamoto M, Kuwashiro Y, Imai A, Motose H, Takahashi T (2019) Complexity and conservation of thermospermine-responsive uORFs of SAC51 family genes in angiosperms. Front. Plant Sci. | doi: 10.3389/fpls.2019.00564 

Okamoto T, Takatani S, Noutoshi Y, Motose H, Takahashi T (2018) Omeprazole enhances mechanical stress-induced root growth reduction in Arabidopsis thaliana. Plant Cell Physiol. 59: 1581-1591

篠原志桜里・本瀬宏康・高橋卓 (2018) ”植物におけるサーモスペルミンの２つの機能” ポリアミン Vol. 5 No. 2: 41-46

Otani K, Ishizaki K, Nishihama R, Takatani S, Kohchi T, Takahashi T, Motose H (2018) An evolutionarily conserved NIMA-related kinase directs rhizoid tip growth in the basal land plant Marchantia polymorpha. Development 145: dev154617

Takahashi T (2018) Thermospermine: an evolutionarily ancient but functionally new compound in plants. Methods Mol. Biol. 1694: 51-59

Takahashi T, Takano A, Kakehi JI (2018) Detection of thermospermine and spermine by HPLC in plants. Methods Mol. Biol. 1694: 69-73 

Masson PH, Takahashi T, Angelini R (2017) Editorial: Molecular mechanisms underlying polyamine functions in plants. Front. Plant Sci. 8: 14

Takatani S, Ozawa S, Yagi N, Hotta T, Hashimoto T, Takahashi Y, Takahashi T, Motose H (2017) Directional cell expansion requires NIMA-related kinase 6 (NEK6)-mediated cortical microtubule destabilization. Sci. Rep. 7: 7826

高橋卓・懸樋潤一・今井章裕 (2017) ”シリーズ 実験手技ノート／TLCを用いた簡便なポリアミン検出” ポリアミン Vol. 4 No. 1: 14-16

Yamamoto M, Takahashi T (2017) Thermospermine enhances translation of SAC51 and SACL1 in Arabidopsis. Plant Signal. Behav. 12: e1276685 

高橋卓・本瀬宏康 (2016) ”サーモスペルミン／木部分化の鍵を握る低分子” 『生物の科学 遺伝』 エヌ・ティー・エス  9月号 pp. 356-360

高橋卓 (2016) コラム ”サーモスペルミン” 浅見忠男・柿本辰男編 『新しい植物ホルモンの科学 第3版』 講談社 pp.192

Cai Q, Fukushima H, Yamamoto M, Ishii N, Sakamoto T, Kurata T, Motose H, Takahashi T (2016) The SAC51 family plays a central role in thermospermine responses in Arabidopsis. Plant Cell Physiol. 57: 1583-1592

Tong W, Imai A, Tabata R, Shigenobu S, Yamaguchi K, Yamada M, Hasebe M, Sawa S, Motose H Takahashi T (2016) Polyamine resistance is increased by mutations in a nitrate transporter gene NRT1.3 (AtNPF6.4) in Arabidopsis thaliana. Front. Plant Sci. 7: 834

Yoshimoto K, Takamura H, Kadota I, Motose H, Takahashi T (2016) Chemical control of xylem differentiation by thermospermine, xylemin, and auxin. Sci. Rep. 6: 21487

Takatani S, Otani K, Kanazawa M, Takahashi T, Motose H (2015) Structure, function, and evolution of plant NIMA-related kinases: Implication for phosphorylation-dependent microtubule regulation. J. Plant Res. 128: 875-891

Takatani S, Hirayama T, Hashimoto T, Takahashi T, Motose H (2015) Abscisic acid induces ectopic outgrowth in epidermal cells through cortical microtubule reorganization in Arabidopsis thaliana. Sci. Rep. 5: 11364

Ogawa E, Yamada Y, Sezaki N, Kosaka S, Kondo H, Kamata N, Abe M, Komeda Y, Takahashi T (2015) ATML1 and PDF2 play a redundant and essential role in Arabidopsis embryo development.Plant Cell Physiol. 56: 1183-1192

Takahashi T, Tong W (2015) Regulation and diversity of polyamine biosynthesis in plants. In Kusano T and Suzuki H (eds) Polyamines: A universal molecular nexus for growth, survival and specialized metabolism, Springer JP, Tokyo, pp 27-44

Kakehi JI, Kawano E, Yoshimoto K, Cai Q, Imai A, Takahashi T (2015) Mutations in ribosomal proteins, RPL4 and RACK1, suppress the phenotype of a thermospermine-deficient mutant of Arabidopsis thaliana. PLoS ONE 10: e0117309   F1000 Prime

Tong W, Yoshimoto K, Kakehi JI, Motose H, Niitsu M, Takahashi T (2014) Thermospermine modulates expression of auxin-related genes in Arabidopsis. Front. Plant Sci. 5: 94 

Kamata N, Sugihara A, Komeda Y, Takahashi T (2013) Allele-specific effects of PDF2 on floral morphology in Arabidopsis thaliana. Plant Signal. Behav. 8: pii: e27417

Kamata N, Okada H, Komeda Y, Takahashi T (2013) Mutations in epidermis-specific HD-ZIP IV genes affect floral organ identity in Arabidopsis thaliana. Plant J. 75: 430-440

Inoue G, Kaneta T, Takayanagi T, Kakehi JI, Motose H, Takahashi T (2013) Determination of polyamines in Arabidopsis thaliana by capillary electrophoresis using salicylaldehyde-5-sulfonate as a derivatizing reagent. Anal. Methods 5: 2854-2859

Motose H, Takatani S, Ikeda T, Takahashi T (2012)NIMA-related kinases regulate directional cell growth and organ development through microtubule function in Arabidopsis thaliana. Plant Signal. Behav. 7: 1552-1555

Yoshimoto K, Noutoshi Y, Hayashi K, Shirasu K, Takahashi T, Motose H (2012) Thermospermine suppresses auxin-inducible xylem differentiation in Arabidopsis thaliana. Plant Signal. Behav. 7: 937-939

Takano A, Kakehi JI, Takahashi T (2012) Thermospermine is not a minor polyamine in the plant kingdom. Plant Cell Physiol. 53: 606-616

Yoshimoto K, Noutoshi Y, Hayashi K, Shirasu K, Takahashi T, Motose H (2012) A chemical biology approach reveals an opposite action between thermospermine and auxin inxylem development in Arabidopsis thaliana. Plant Cell Physiol. 53: 635-645

Motose H, Hamada T, Yoshimoto K, Murata T, Hasebe M, Watanabe Y, Hashimoto T, Sakai T, Takahashi T (2011) NIMA-related kinases 6, 4, and 5 interact with each other to regulate microtubule organization during epidermal cell expansion in Arabidopsis thaliana. Plant J. 67: 993-1005

Ichihashi Y, Kawade K, Usami T, Horiguchi G, Takahashi T, Tsukaya H (2011) Key proliferative activity in the junction between the leaf blade and leaf petiole of Arabidopsis thaliana. Plant Physiol. 157: 1151-1162

Shirakawa M, Ueda H, Shimada T, Koumoto Y, Shimada TL, Kondo M, Takahashi T, Okuyama Y, Nishimura M, Hara-Nishimura I (2010) Arabidopsis Qa-SNARE SYP2 proteins localized to different subcellular regions function redundantly in vacuolar protein sorting and plant development. Plant J. 64: 924-935

Kakehi JI, Kuwashiro Y, Motose H, Igarashi K, Takahashi T (2010) Norspermine substitutes for thermospermine in the control of stem elongation in Arabidopsis thaliana. FEBS Lett. 584: 3042-3046

Takahashi T, Kakehi JI (2010) Polyamines: Ubiquitous Polycations with Unique Roles in Growth and Stress Responses. Ann. Bot. 105: 1-6