Researchgate Profile (Tae Hwan Shin) 

GoogleScholar Profile (Tae Hwan Shin)

ScholarGPS (Tae Hwan Shin)


Jin Soo Choi, Soyoung An, Tae Hwan Shin, Wan-Seob Cho, June-Woo Park

Merkel cells and corpuscles of Stannius as putative targets for polyethylene terephthalate microfibers in sheepshead minnow larvae. Ecotoxicology and Environmental Safety. 2024 Sep 14. 285, 117024 

(Co-corresponding author, Impact Factor : 6.8)*

ISSN: 0147-6513


Su Hwan Park, Gyuri Kim, Gi-Eun Yang, Hye Jin Yun, Tae Hwan Shin, Sun Tae Kim, Kyuhong Lee, Hyuk Soon Kim, Seok-Ho Kim, Sun-Hee Leem, Wan-Seob Cho, Jong-Ho Lee

Disruption of phosphofructokinase activity and aerobic glycolysis in human bronchial epithelial cells by atmospheric ultrafine particulate matter. Journal of Hazardous Materials. 2024 Feb 15 464, 132966 

(Impact Factor : 13.6)

ISSN: 1873-3336


Tae Hwan Shin, Gwang Lee

Reduced lysosomal activity and increased amyloid beta accumulation in silica‑coated magnetic nanoparticles‑treated microglia. Archives of Toxicology. 2024 Jan 31, 98, 121-134 

(Impact Factor : 6.1)

ISSN: 0340-5761


Hye Jin Yun, Min Li, Dong Guo, So Mi Jeon, Su Hwan Park, Je Sun Lim, Su Bin Lee, Rui Liu, Linyong Du, Seok‑Ho Kim, Tae Hwan Shin, Seong‑il Eyun, Yun‑Yong Park, Zhimin Lu, Jong‑Ho Lee

AMPK‑HIF‑1α signaling enhances glucose‑derived de novo serine biosynthesis to promote glioblastoma growth. Journal of Experimental & Clinical Cancer Research. 2023 Dec 15, 42, 340 

(Impact Factor : 11.3)

ISSN: 1756-9966 


Tae Hwan Shin, Seok Gi Kim, Moongi Ji, Do Hyeon Kwon, Ji Su Hwang, Nimisha Pradeep George, Dube Solomon Ergando, Chan Bae Park, Man Jeong Paik, Gwang Lee

Diesel-derived PM2.5 induces impairment of cardiac movement followed by mitochondria dysfunction in cardiomyocytes. Frontiers in Endocrinology. 2022 Sep 28, 13, 999475 

(Impact Factor : 5.2)

ISSN: 1664-2392


Tae Hwan Shin, Da Yeon Lee, Yong Eun Jang, Do Hyeon Kwon, Ji Su Hwang, Seok Gi Kim, Chan Seo, Man Jeong Paik, Ju Yeon Lee, Jin Young Kim, Seokho Park, Sung-E Choi, Shaherin Basith, Myeong Ok Kim, Gwang Lee

Reduction in the Migration Activity of Microglia Treated with Silica-Coated Magnetic Nanoparticles and their Recovery Using Citrate. Cells. 2022 Aug 3, 11, 2393 

(Impact Factor : 6.0)

ISSN: 2073-4409


Shaherin Basith, Balachandran Manavalan, Tae Hwan Shin, Chan Bae Park, Wang-Soo Lee, Jaetaek Kim, Gwang Lee

The Impact of Fine Particulate Matter 2.5 on the Cardiovascular System: A Review of the Invisible Killer. Nanomaterials. 2022 Aug 2, 12, 2656 

(Impact Factor : 5.3)

ISSN: 2079-4991


Ji Su Hwang, Seok Gi Kim, Tae Hwan Shin, Yong Eun Jang, Do Hyeon Kwon, Gwang Lee

Development of Anticancer Peptides Using Artificial Intelligence and Combinational Therapy for Cancer Therapeutics. Pharmaceutics. 2022 May 6, 14, 997

(Co-first author, Impact Factor : 5.4)

ISSN: 1999-4923


Sung-E Choi, Yoonjung Hwang, Soo-Jin Lee, Hyunkyung Jung, Tae Hwan Shin, Youngho Son, Seokho Park, Seung Jin Han, Hae Jin Kim, Kwan Woo Lee, Gwang Lee, Jongsook Kim Kemper, Hyun Kyu Song, Yup Kang

Mitochondrial protease ClpP supplementation ameliorates diet-induced NASH in mice. Journal of Hepatology. 2022 Sep, 77(3), 735-747

(Impact Factor : 25.7)

ISSN: 0168-8278


Do Hyeon Kwon, Ji Su Hwang, Seok Gi Kim, Yong Eun Jang, Tae Hwan Shin, Gwang Lee

Cerebrospinal Fluid Metabolome in Parkinson’s Disease and Multiple System Atrophy. International Journal of Molecular Sciences. 2022 Feb. 7, 23, 1879

(Co-corresponding author, Impact Factor : 5.6)

ISSN: 1422-0067


Suresh Kumar Chakkarapani, Tae Hwan Shin, Seungah Lee, Kyung-Soo Park, Gwang Lee, Seong Ho Kang

Quantifying Intracellular Trafficking of Silica-coated Magnetic Nanoparticles in Live Single Cells by Site-specific Direct Stochastic Optical Reconstruction Microscopy. Journal of Nanobiotechnology. 2021 Nov. 29, 19, 398 

(Co-first author, Impact Factor : 10.2)

ISSN: 1477-3155


Tae Hwan Shin, Balachandran Manavalan, Da Yeon Lee, Shaherin Basith, Chan Seo, Man Jeong Paik, Sang-Wook Kim, Haewoon Seo, Ju Yeon Lee, Jin Young Kim, A Young Kim, Jee Min Chung, Eun Joo Baik, Seong Ho Kang, Dong-Kug Choi, Yup Kang, M. Maral Mouradian, Gwang Lee

Silica-coated magnetic-nanoparticle-induced cytotoxicity is reduced in microglia by glutathione and citrate identified using integrated omics analysis. Particle and Fibre Toxicology. 2021 Nov. 25, 18, 42 

(Impact Factor : 10.0)

ISSN: 1743-8977


Tae Hwan Shin, Saraswathy Nithiyanandam, Da Yeon Lee, Do Hyeon Kwon, Ji Su Hwang, Seok Gi Kim, Yong Eun Jang, Shaherin Basith, Sungsu Park, Jung-Soon Mo, Gwang Lee

Analysis of Nanotoxicity with Integrated Omics and Mechanobiology. Nanomaterials. 2021 Sep. 13, 11(9), 2385 

(Impact Factor : 5.3)

ISSN: 2079-4991


Da Yeon Lee, Sung Eun Lee, Do Hyeon Kwon, Saraswathy Nithiyanandam, Mi Ha Lee, Ji Su Hwang, Shaherin Basith, Jung Hwan Ahn, Tae Hwan Shin, Gwang Lee

Strategies to Improve the Quality and Freshness of Human Bone Marrow-Derived Mesenchymal Stem Cells for Neurological Diseases. Stem cells International. 2021 Sep, 2020, 8444599

(Co-corresponding author, Impact Factor : 4.3)

ISSN: 1687-966X


Shaherin Basith, Hye Jin Chang, Saraswathy Nithiyanandam, Tae Hwan Shin, Balachandran Manavalan, Gwang Lee

Recent trends on the development of machine learning approaches for the prediction of lysine acetylation sites. Current Medicinal Chemistry. 2021 Sep, 2, 29(2), 235-250 

(Impact Factor : 4.1)

ISSN: 0929-8673


Tae Hwan Shin, Da Yeon Lee, Balachandran Manavalan, Shaherin Basith, Yun-Cheol Na, Cheolho Yoon, Hyeon-Seong Lee, Man Jeong Paik, Gwang Lee

Silica-coated magnetic nanoparticles activate microglia and induce neurotoxic D-serine secretion. Particle and Fibre Toxicology. 2021 Aug, 18, 30 

(Impact Factor : 10.0)

ISSN: 1743-8977


Shaherin Basith, Balachandran Manavalan, Tae Hwan Shin, Gwang Lee

Mapping the Intramolecular Communications among Different Glutamate Dehydrogenase States Using Molecular Dynamics. Biomolecules. 2021 May, 11(6) 798 

(Impact Factor : 5.5)

ISSN: 2218-273X


Tae Hwan Shin, Abdurazak Aman Ketebo, Da Yeon Lee, Seungah Lee, Seong Ho Kang, Shaherin Basith, Balachandran Manavalan, Do Hyeon Kwon, Sungsu Park. Gwang Lee

Decrease in membrane fluidity and traction force induced by silica-coated magnetic nanoparticles. Journal of Nanobiotechnology. 2021 Jan., 21, 19 

(Impact Factor : 10.2)

ISSN: 1477-3155


Shaherin Basith, Balachandran Manavalan, Tae Hwan Shin, Da Yeon Lee, Gwang Lee

Evolution of Machine Learning Algorithms in the Prediction and Design of Anticancer Peptides. Current Protein and Peptide Science. 2020 Dec 31, 21, pp 1242-1250 

(Impact Factor : 2.8)

ISSN: 1875-5550


Abdurazak Aman Ketebo, Tae Hwan Shin, Myeongjun Jun, Gwang Lee, Sungsu Park

Effect of silica-coated magnetic nanoparticles on rigidity sensing of human embryonic kidney cells. Journal of Nanobiotechnology. 2020 Nov.18, 18, 170

(Co-first author, Impact Factor : 10.2)

ISSN: 1477-3155


Balachandran Manavalan, Shaherin Basith, Tae Hwan Shin, Gwang Lee

Computational prediction of species-specific yeast DNA replication origin via iterative feature representation. Briefings in Bioinformatics. 2020 Nov. 25, bbaa304

(Impact Factor : 9.5)

ISSN: 1467-5463


Balachandran Manavalan, Md. Mehedi Hasan, Shaherin Basith, Vijayakumar Gosu, Tae Hwan Shin, Gwang Lee

Empirical Comparison and Analysis of Web-Based DNA N4-Methylcytosine Site Prediction Tools. Molecular Therapy: Nucleic Acids. 2020 Dec. 4, 22, pp 406-420

(Impact Factor : 8.8)

ISSN: 2162-2531


Tae Hwan Shin, Da Yeon Lee, Shaherin Basith, Balachandran Manavalan, Man Jeong Paik, Igor Rybinnik, M. Maral Mouradian, Jung Hwan Ahn, Gwang Lee

Metabolome Changes in Cerebral Ischemia. Cells. 2020 Jul. 7, 9(7), 1630

(Impact Factor : 6.0)

ISSN: 2073-4409


Shaherin Basith, Balachandran Manavalan, Tae Hwan Shin, Gwang Lee

Machine intelligence in peptide therapeutics: A next‐generation tool for rapid disease screening. Medicinal Research Review. 2020 Jan. 10, 40(4), pp 1276-1314

(Impact Factor : 13.3)

ISSN: 0198-6325


Balachandran Manavalan, Shaherin Basith, Tae Hwan Shin, Da Yeon Lee, Leyi Wei, Gwang Lee

4mCpred-EL: An Ensemble Learning Framework for Identification of DNA N4-Methylcytosine Sites in the Mouse Genome. Cells. 2019 Oct. 28, 8(11), 1332

(Impact Factor : 6.0)

ISSN: 2073-4409


Tae Hwan Shin, Da Yeon Lee, Abdurazak Aman Ketebo, Seungah Lee, Balachandran Manavalan, Shaherin Basith, Chanyoung Ahn, Seong Ho Kang,

Sungsu Park, Gwang Lee

Silica-Coated Magnetic Nanoparticles Decrease Human Bone Marrow-Derived Mesenchymal Stem Cell Migratory Activity by Reducing Membrane Fluidity and Impairing Focal Adhesion. Nanomaterials. 2019 Oct. 17, 9(10), 1475

(Impact Factor : 5.3)

ISSN: 2079-4991


Balachandran Manavalan, Shaherin Basith, Tae Hwan Shin, Leyi Wei, Gwang Lee

mAHTPred: a sequence-based meta-predictor for improving the prediction of anti-hypertensive peptides using effective feature representation. Bioinformatics. 2019 Aug. 15, 35(16), pp 2757-2765

(Impact Factor : 5.8)

ISSN: 1367-4803


Shaherin Basith, Balachandran Manavalan, Tae Hwan Shin, Gwang Lee

SDM6A: A Web-Based Integrative Machine-Learning Framework for Predicting 6mA Sites in the Rice Genome. Molecular Therapy: Nucleic Acids. 2019 Dec 6. 18, pp 131-141

(Impact Factor : 8.8)

ISSN: 2162-2531


Balachandran Manavalan, Shaherin Basith, Tae Hwan Shin, Leyi Wei, Gwang Lee

AtbPpred: A Robust Sequence-Based Prediction of Anti-Tubercular Peptides Using Extremely Randomized Trees. Computational and Structural Biotechnology Journal. 2019 Jul. 3. 17, pp 972–981

(Impact Factor : 6.0)

ISSN: ‎2001-0370


Jeonghun Han, Wanyoung Lim, Daeun You, Yisun Jeong, Sangmin Kim, Jeong Eon Lee, Tae Hwan Shin, Gwang Lee, Sungsu Park

Chemoresistance in the Human Triple-Negative Breast Cancer Cell Line MDA-MB-231 Induced by Doxorubicin Gradient Is Associated with Epigenetic Alterations in Histone Deacetylase. Journal of Oncology. 2019 Jun. 2, 2019, 1345026

ISSN: ‎1687-8450


Balachandran Manavalan, Shaherin Basith, Tae Hwan Shin, Leyi Wei, Gwang Lee

Meta-4mCpred: A Sequence-Based Meta-Predictor for Accurate DNA 4mC Site Prediction Using Effective Feature Representation. Molecular Therapy: Nucleic Acids. 2019 Jun. 7, 16, pp 733-744

(Impact Factor : 8.8)

ISSN: 2162-2531


Shaherin Basith, Balachandran Manavalan, Tae Hwan Shin, Gwang Lee

A Molecular Dynamics Approach to Explore the Intramolecular Signal Transduction of PPAR-α. International Journal of Molecular Sciences. 2019 Apr. 3, 20(7), 1666

(Impact Factor : 5.6)

ISSN: 1422-0067


Tae Hwan Shin, Chan Seo, Da Yeon Lee, Moongi Ji, Balachandran Manavalan, Shaherin Basith, Suresh Kumar Chakkarapani, Seong Ho Kang, Gwang Lee, Man Jeong Paik, Chan Bae Park

Silica-coated magnetic nanoparticles induce glucose metabolic dysfunction in vitro via the generation of reactive oxygen species. Archives of Toxicology. 2019 Feb. 8, 93(5), pp 1201-1212

(Impact Factor : 6.1)

ISSN: 0340-5761


Hyeon-Seong Lee, Chan Seo, Yun-Ho Hwang, Tae Hwan Shin, Hyung-Jin Park, Youngbae Kim, Moongi Ji, Jeuk Min, Subin Choi, Hangun Kim, Ae Kyung Park, Sung-Tae Yee, Gwang Lee, Man-Jeong Paik

Metabolomic approaches to polyamines including acetylated derivatives in lung tissue of mice with asthma. Metabolomics. 2019 Jan. 5, 15(8), pp1-9

(Impact Factor : 3.6)

ISSN: 1573-3882


Shaherin Basith, Balachandran Manavalan, Tae Hwan Shin, Gwang Lee

iGHBP: Computational identification of growth hormone binding proteins from sequences using extremely randomised tree. Computational and Structural Biotechnology Journal. 2018 Oct. 24, 16; 412-420 doi: /10.1016/j.csbj.2018.10.007

(Impact Factor : 6.0)

ISSN: 2001-0370


Balachandran Manavalan, Tae Hwan Shin, Myeong Ok Kim, Gwang Lee

PIP-EL: A New Ensemble Learning Method for Improved Proinflammatory Peptide Predictions. Frontiers in Immunology. 2018 Jul. 31. 9, 1783 doi: 10.3389/fimmu.2018.01783

(Impact Factor : 7.3)

ISSN: 1664-3224


Da Yeon Lee, Moon Suk Jin, Balachandran Manavalan, Hak Kyun Kim, Jun Hyeok Song, Tae Hwan Shin, Gwang Lee

Bidirectional Transcriptome Analysis of Rat Bone Marrow-Derived Mesenchymal Stem Cells and Activated Microglia in an In Vitro Coculture System. Stem cells International, 2018 Jul. 29, 2018, 6126413, doi:10.1155/2018/6126413

(Co-corresponding author, Impact Factor : 4.3)

ISSN: 1687-966X


Balachandran Manavalan, Rajiv Gandhi Govindaraj, Tae Hwan Shin, Myeong Ok Kim, Gwang Lee

iBCe-eL: A New ensemble Learning Framework for Improved Linear B-Cell epitope Prediction. Frontiers in Immunology. 2018 Jul. 27, 9, 1695 doi: 10.3389/fimmu.2018.01695

(Impact Factor : 7.3)

ISSN: 1664-3224


Balachandran Manavalan, Sathiyamoorthy Subramaniyam, Tae Hwan Shin, Myeong Ok Kim, Gwang Lee

Machine-learning-based prediction of cell-penetrating peptides and their uptake efficiency with improved accuracy. Journal of Proteome Research. 2018 Jun. 12, 17(8), 2715-2726. doi: 10.1021/acs.jproteome.8b00148

(Impact Factor : 4.4)

ISSN: 1535-3893


Balachandran Manavalan, Tae Hwan Shin, Myeong Ok Kim, Gwang Lee

AIPpred: Sequence-Based Prediction of Anti-Inflammatory Peptides Using Random Forest. Frontiers in Pharmacology. 2018 Mar. 27. 9, 276. doi: 10.3389/fphar.2018.00276

(Impact Factor : 5.6)

ISSN: 1663-9812


Balachandran Manavalan, Tae Hwan Shin, Gwang Lee

PVP-SVM: Sequence-Based Prediction of Phage Virion Proteins Using a Support Vector Machine. Frontiers in Microbiology. 2018 Mar. 16. 9, 476. doi: 10.3389/fmicb.2018.00476

(Impact Factor : 5.2)

ISSN: 1664-302X


Jeonghun Han, Seunghan Oh, Hong-Hoa Hoang, Dao Thi Thuy Nguyen, Wanyoung Lim, Tae Hwan Shin, Gwang Lee, Sungsu Park

Recapitulation of cancer stem cell niches in glioblastoma on 3D microfluidic cell culture devices under gravity-driven perfusion. Journal of Industrial and Engineering Chemistry. 2018 Jun. 25, 62, 352-361 doi.org/10.1016/j.jiec.2018.01.015

(Impact Factor : 6.1)

ISSN: 1226-086X


Tae Hwan Shin, Da Yeon Lee, Hyeon-seong Lee, Hyung Jin Park, Moon Suk Jin, Man-jeong Paik, Balachandran Manavalan, Jung-soon Mo, Gwang Lee

Integration of metabolomics and transcriptomics in nanotoxicity studies. BMB Reports. 2018 Jan. 51(1):14-20

(Impact Factor : 3.8)

ISSN: 1976-670X


Kim HA, Lee HS, Shin TH, Jung JY, Baek WY, Park HJ, Lee G, Paik MJ, Suh CH

Polyamine patterns in plasma of patients with systemic lupus erythematosus and fever. Lupus. 2018 May, 27(6), 930-938. doi: 10.1177/0961203317751860

(Impact Factor : 2.6)

ISSN: 0961-2033


Tae Hwan Shin, Hyoun-Ah Kim, Ju-Yang Jung, Wook-Young Baek, Hyeon-Seong Lee, Hyung Jin Park, Jeuk Min, Man-Jeong Paik, Gwang Lee, Chang-Hee Suh

Analysis of the free fatty acid metabolome in the plasma of patients with systemic lupus erythematosus and fever. Metabolomics. 2018 Jan. 14(1), 14

(Impact Factor : 3.6)

ISSN: 1573-3882


Balachandran Manavalan, Tae Hwan Shin, Gwang Lee

DHSpred: support-vector-machine-based human DNase I hypersensitive sites prediction using the optimal features selected by random forest. Oncotarget. 2017 Nov. 24. 9(2), 1944-1956. doi.org/10.1101/224527

ISSN: 1949-2553


Chan Seo, Yun-Ho Hwang, Hyeon-Seong Lee, Youngbae Kim, Tae Hwan Shin, Gwang Lee, Young-Jin Son, Hangun Kim, Sung-Tae Yee, Ae Kyung Park, Man-Jeong Paik

Metabolomic study for monitoring of biomarkers in mouse plasma with asthma by gas chromatography-mass spectrometry. Journal of Chromatography B. 2017 Aug. 30. 1063, 156-162

(Impact Factor : 3.0)

ISSN: 1570-0232


Balachandran Manavalan, Shaherin Basith, Tae Hwan Shin, Sun Choi, Myeong Ok Kim, Gwang Lee

MLACP: machine-learning-based prediction of anticancer peptides. Oncotarget. 2017 Aug. 19 8(44), 77121-77136

ISSN: 1949-2553

Tae Hwan Shin, Seungah Lee, Ki Ryung Choi, Da Yeon Lee, Yongman Kim, Man Jeong Paik, Chan Seo, Suk Kang, Moon Suk Jin, Tae Hyeon Yoo, Seong Ho Kang, Gwang Lee

Quality and freshness of human bone marrow-derived mesenchymal stem cells decrease over time after trypsinization and storage in phosphate-buffered saline. Scientific reports. 2017 Apr. 24, 7, 1106

(Impact Factor : 4.6)

ISSN: 2045-2322


Geetika Phukan, Tae Hwan Shin, Jeom Soon Shim, Man Jeong Paik, Jin-Kyu Lee, Sangdun Choi, Yong Man Kim, Seong Ho Kang, Hyung Sik Kim, Yup Kang, Soo Hwan Lee, M. Maral Mouradian, Gwang Lee

Silica-coated magnetic nanoparticles impair proteasome activity and increase the formation of cytoplasmic inclusion bodies. Scientific reports, 2016 Jul, 6:29095

(Co-first author, Impact Factor : 4.6)

ISSN: 2045-2322


Tae Hwan Shin, Geetika Phukan, Jeom Soon Shim, Duc-Toan Nguyen, Yongman Kim, Justin D. Oh-Lee, Hyeon-Seong Lee, Man Jeong Paik, Gwang Lee

Restoration of Polyamine Metabolic Patterns in In Vivo and In Vitro Model of Ischemic Stroke following Human Mesenchymal Stem Cell Treatment. Stem cells International, 2016 Jun, 4612531

(Co-first author, Impact Factor : 4.3)

ISSN: 1687-966X


Young Bok Bae, Hye Kyeong Jang, Tae Hwan Shin, Geetika Phukan, Thanh Tinh Tran, Gwang Lee, Wook Ryol Hwang, Ju Min Kim

Microfluidic assessment of mechanical cell damage by extensional stress. Lab on a Chip, 2016 Jan, 16, 96–103

(Impact Factor : 6.1)

ISSN: 1473-0197


Ye-Jin Kim, Jeomil Bae, Tae-Hwan Shin, Se Hun Kang, Moonkyoung Jeong, Yunho Han, Ji-Ho Park, Seok-Ki Kim, Yong-Sung Kim

Immunoglobulin Fc-fused, neuropilin-1-specific peptide shows efficient tumor tissue penetration and inhibits tumor growth via anti-angiogenesis. Journal of Controlled Release. 2015 Aug, 216:56-68

(Impact Factor : 10.8)

ISSN: 0168-3659


Tae-Hwan Shin, Eun-Sil Sung, Ye-Jin Kim, Ki-Su Kim, Se-Ho Kim, Seok-Ki Kim, Young-Don Lee, Yong-Sung Kim

Enhancement of the tumor penetration of monoclonal antibody by fusion of a neuropilin-targeting peptide improves the anti-tumor efficacy. Molecular Cancer Therapeutics. 2014 Mar, 13(3):651-661

(Impact Factor : 5.7)

Highlighted article of issue.

ISSN: 1535-7163


Aeyung Kim, Tae-Hwan Shin, Seung-Min Shin, Chuong D. Pham, Dong-Ki Choi, Myung-Hee Kwon, Yong-Sung Kim

Cellular internalization mechanism and intracellular trafficking of filamentous M13 phages displaying a cell-penetrating transbody and TAT peptide. PLoS ONE. 2012 Dec 14, 7(12):e51813

(Co-first author, Impact Factor : 3.7)

ISSN: 1932-6203


*: Based on Journal Citation Reports 2023