LIVE project
LIVE project
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LIVE (Lipidome of Extracellular Vesicles in hypoxic pancreatic cancer) is a research project focused on characterizing the lipid composition of extracellular vesicles (EVs) secreted by pancreatic ductal adenocarcinoma (PDAC) cells under hypoxic conditions. Using untargeted lipidomics, the study aims to identify lipid species enriched in tumor-derived EVs that may play roles in membrane dynamics, cell signaling, and tumor microenvironment modulation.
The goal of LIVE is to uncover lipid-based molecular signatures with potential value as diagnostic biomarkers for early PDAC detection and to better understand how EV lipids contribute to cancer progression under hypoxia.
LIVE (Lipidome of Extracellular Vesicles in hypoxic pancreatic cancer) is a research project focused on characterizing the lipid composition of extracellular vesicles (EVs) secreted by pancreatic ductal adenocarcinoma (PDAC) cells under hypoxic conditions. Using untargeted lipidomics, the study aims to identify lipid species enriched in tumor-derived EVs that may play roles in membrane dynamics, cell signaling, and tumor microenvironment modulation.
The goal of LIVE is to uncover lipid-based molecular signatures with potential value as diagnostic biomarkers for early PDAC detection and to better understand how EV lipids contribute to cancer progression under hypoxia.
Discover the LIVE project poster, showcased at national and international scientific conferences.
Discover the LIVE project poster, showcased at national and international scientific conferences.
Click on the poster miniature to explore the LIVE project results
Meeting conclusivo di progetto THE
October 28-29, 2025 - Firenze (IT)
Meeting conclusivo di progetto THE
October 28-29, 2025 - Firenze (IT)
Title: LIpidome of extracellular VEscicles in hypoxic pancreatic cancer cells (LIVE)
Title: LIpidome of extracellular VEscicles in hypoxic pancreatic cancer cells (LIVE)
Authors: Vito Nettis, Giovanni Ventura, Andrea Castellaneta, Liam McDonnell, NoaNdimurwanko, Francesco Greco, Tommaso Cataldi, Cosima Damiana Calvano
Authors: Vito Nettis, Giovanni Ventura, Andrea Castellaneta, Liam McDonnell, NoaNdimurwanko, Francesco Greco, Tommaso Cataldi, Cosima Damiana Calvano
XLII Convegno Nazionale della Divisione di Chimica Organica - CDCO 2025
September 21-25, 2025- Cagliari (IT)
XLII Convegno Nazionale della Divisione di Chimica Organica - CDCO 2025
September 21-25, 2025- Cagliari (IT)
Title: Synthesis of novel reactive MALDI matrices for the analysis of low molecular weight metabolites in hypoxic pancreatic cancer extracellular vesicles
Title: Synthesis of novel reactive MALDI matrices for the analysis of low molecular weight metabolites in hypoxic pancreatic cancer extracellular vesicles
Authors: Cosima Damiana Calvano, Andrea Cinnirella, Antonio Monopoli, Vito Nettis, Giovanni Ventura, NoaNdimurwanko, Francesco Greco, Liam McDonnell
Authors: Cosima Damiana Calvano, Andrea Cinnirella, Antonio Monopoli, Vito Nettis, Giovanni Ventura, NoaNdimurwanko, Francesco Greco, Liam McDonnell
XXXI Congresso della Divisione di Chimica Analitica della Società Chimica Italiana (SCI)
September 7-11, 2025- Pisa (IT)
XXXI Congresso della Divisione di Chimica Analitica della Società Chimica Italiana (SCI)
September 7-11, 2025- Pisa (IT)
Title: Phospho- and sphingo-lipidome of extracellular vesicles from pancreatic cancer cells
Title: Phospho- and sphingo-lipidome of extracellular vesicles from pancreatic cancer cells
Authors: Vito Nettis, Giovanni Ventura, Liam McDonnell, NoaNdimurwanko, Francesco Greco, Tommaso Cataldi, Cosima Damiana Calvano
Authors: Vito Nettis, Giovanni Ventura, Liam McDonnell, NoaNdimurwanko, Francesco Greco, Tommaso Cataldi, Cosima Damiana Calvano
MS J DAY 2025
May 22-23, 2025 - Pisa (IT)
MS J DAY 2025
May 22-23, 2025 - Pisa (IT)
Title: Lipidome of extracellular vesicles in hypoxic pancreatic cancer
Title: Lipidome of extracellular vesicles in hypoxic pancreatic cancer
Authors: Vito Nettis, Giovanni Ventura, Liam McDonnell, NoaNdimurwanko, Francesco Greco, Tommaso Cataldi, Cosima Damiana Calvano
Authors: Vito Nettis, Giovanni Ventura, Liam McDonnell, NoaNdimurwanko, Francesco Greco, Tommaso Cataldi, Cosima Damiana Calvano
de.NBI Spring School in Bioinformatics for Lipidomics
March 24-28, 2025 - Bielefeld (DE)
de.NBI Spring School in Bioinformatics for Lipidomics
March 24-28, 2025 - Bielefeld (DE)
Title: Exploring Lipid Diversity and Structure: From Hidden Lipids to Biomedical Insights
Title: Exploring Lipid Diversity and Structure: From Hidden Lipids to Biomedical Insights
Authors: Giovanni Ventura, Cosima Damiana Calvano
Authors: Giovanni Ventura, Cosima Damiana Calvano
MASSA 2025
June 16-18, 2025 - Taranto (IT)
MASSA 2025
June 16-18, 2025 - Taranto (IT)
Title: Lipidome of extracellular vesicles in hypoxic pancreatic cancer
Title: Lipidome of extracellular vesicles in hypoxic pancreatic cancer
Authors: Vito Nettis, Giovanni Ventura, Liam McDonnell, NoaNdimurwanko, Francesco Greco, Tommaso Cataldi, Cosima Damiana Calvano
Authors: Vito Nettis, Giovanni Ventura, Liam McDonnell, NoaNdimurwanko, Francesco Greco, Tommaso Cataldi, Cosima Damiana Calvano
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