LIVE project
LIVE project
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LIVE (Lipidome of Extracellular Vesicles in hypoxic pancreatic cancer) is a research project focused on characterizing the lipid composition of extracellular vesicles (EVs) secreted by pancreatic ductal adenocarcinoma (PDAC) cells under hypoxic conditions. Using untargeted lipidomics, the study aims to identify lipid species enriched in tumor-derived EVs that may play roles in membrane dynamics, cell signaling, and tumor microenvironment modulation.
The goal of LIVE is to uncover lipid-based molecular signatures with potential value as diagnostic biomarkers for early PDAC detection and to better understand how EV lipids contribute to cancer progression under hypoxia.
LIVE (Lipidome of Extracellular Vesicles in hypoxic pancreatic cancer) is a research project focused on characterizing the lipid composition of extracellular vesicles (EVs) secreted by pancreatic ductal adenocarcinoma (PDAC) cells under hypoxic conditions. Using untargeted lipidomics, the study aims to identify lipid species enriched in tumor-derived EVs that may play roles in membrane dynamics, cell signaling, and tumor microenvironment modulation.
The goal of LIVE is to uncover lipid-based molecular signatures with potential value as diagnostic biomarkers for early PDAC detection and to better understand how EV lipids contribute to cancer progression under hypoxia.
Discover the LIVE project poster, showcased at national and international scientific conferences.
Discover the LIVE project poster, showcased at national and international scientific conferences.
Click on the poster miniature to explore the LIVE project results
MS J DAY 2025
May 22-2, 2025 - Pisa (IT)
MS J DAY 2025
May 22-2, 2025 - Pisa (IT)
Title: Lipidome of extracellular vesicles in hypoxic pancreatic cancer
Title: Lipidome of extracellular vesicles in hypoxic pancreatic cancer
Authors: Vito Nettis, Giovanni Ventura, Liam McDonnell, NoaNdimurwanko, Francesco Greco, Tommaso Cataldi, Cosima Damiana Calvano
Authors: Vito Nettis, Giovanni Ventura, Liam McDonnell, NoaNdimurwanko, Francesco Greco, Tommaso Cataldi, Cosima Damiana Calvano
de.NBI Spring School in Bioinformatics for Lipidomics
March 24-28, 2025 - Bielefeld (DE)
de.NBI Spring School in Bioinformatics for Lipidomics
March 24-28, 2025 - Bielefeld (DE)
Title: Exploring Lipid Diversity and Structure: From Hidden Lipids to Biomedical Insights
Title: Exploring Lipid Diversity and Structure: From Hidden Lipids to Biomedical Insights
Authors: Giovanni Ventura, Cosima Damiana Calvano
Authors: Giovanni Ventura, Cosima Damiana Calvano
MASSA 2025
June 16-18, 2025 - Taranto (IT)
MASSA 2025
June 16-18, 2025 - Taranto (IT)
Title: Lipidome of extracellular vesicles in hypoxic pancreatic cancer
Title: Lipidome of extracellular vesicles in hypoxic pancreatic cancer
Authors: Vito Nettis, Giovanni Ventura, Liam McDonnell, NoaNdimurwanko, Francesco Greco, Tommaso Cataldi, Cosima Damiana Calvano
Authors: Vito Nettis, Giovanni Ventura, Liam McDonnell, NoaNdimurwanko, Francesco Greco, Tommaso Cataldi, Cosima Damiana Calvano
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