In the Kumsta Lab, we are dedicated to advancing our understanding of the molecular mechanisms that drive aging and disease. Our research leverages cutting-edge techniques in genetics, cell biology, and proteomics to uncover new insights and potential therapies, using our favorite model organism, the nematode C. elegans, as well as cell culture and human tissues.

As we age, the risk of developing age-related disorders, such as neurodegenerative diseases, increases due to the cellular accumulation of damaged biomolecules, including protein aggregates, which contribute to cellular decline. Activating cytoprotective mechanisms, such as autophagy and stress responses, is crucial for enhancing cellular function and preventing aging-induced dysfunction. Uncovering these mechanisms that help maintain cellular integrity during aging is a critical step toward developing new strategies to preserve cellular homeostasis and overall health, with the potential to extend healthspan and eliminate age-related diseases.

Our team is committed to fostering a collaborative and innovative environment where scientific curiosity drives meaningful discoveries. Whether you are a prospective collaborator, student, or simply interested in our work, we invite you to explore our website to learn more about our research, meet our team, and stay updated on our latest news and achievements.