Dr. Paul Kubes, PhD

Professor, Department of Physiology and Pharmacology; Head, University of Calgary's research strategy for Infections, Inflammation, and Chronic Diseases in the Changing Environment (IICD); Canada Research Chair in Leukocyte Recruitment in Inflammatory Disease

The Kubes lab is committed to understanding complex immune responses in the context of human clinical disease. Our primary focus is to directly visualize the roles of immune cells during inflammation, infection and tissue injury. Our lab is leading the way in directly imaging the immune system using cutting edge technology, including spinning-disk confocal, resonant-scanning confocal, and multi-photon microscopy. By imaging complex cellular behaviors in real time, both in vitro and in vivo, we can now begin to understand how immune cells, such as neutrophils, monocytes, macrophages, eosinophils, and iNKT cells, function under physiological and pathological disease states.

We are recruiting talented postdocs to join our lab, for more information please read our advertisement!

Cover art by A. Neupane, PhD

White: Alveoli (PDPN)
Red: Capillaries (CD31)
Green: Alveolar Macrophages (SiglecF)

Lab Updates

August 2022

Congratulations to Dr. Rachel Kratofil for crushing her PhD defense! Check out her Nature paper to learn more about how monocytes produce ghrelin to regulate wound healing in the skin after Staph aureus infection.

Welcome to Dr. Lilian Salm joining us from Switzerland!

May 2022

Dr. Nina Noskovicova is our latest recruit who will be working on peritoneal macrophages. Welcome Nina!

January 2022

Welcome to Dr. Marie Siwicki who just joined the lab as a new postdoctoral fellow!

May 2021

Undergraduate students Rose Binley-Ewing, Matt O'Neill, and Darren Nguyen have joined our lab for the summer semester, welcome all!

April 2021

A huge congratulations to Dr. Arpan Neupane for successfully defending his PhD this month! To read about Arpan's research, check out his Cell paper on visualizing the function and behavior of alveolar macrophages. Arpan will begin his postdoctoral fellowship at Stanford University later this summer.

March 2021

Dr. Raymond Shim came all the way from Australia to join our lab as a new postdoctoral fellow, welcome Ray!

Did you know that peritoneal macrophages can behave just like platelets in the body cavity during sterile injury? Read up on Dr. Joel Zindel's recent work published in Science.

January 2021

We are recruiting talented postdocs to join our lab, for more information please visit our advertisement!

Welcoming Wendy Zhang and Oscar Tejada as new MSc students in the lab.

September 2019

We have a new grad student, welcome Brian Shim from Vancouver, BC!

November 2018

Welcoming Dr. Ysbrand Nusse, postdoctoral fellow, and visiting PhD student Dr. Joel Zindel, MD, to join our lab family!

September 2018

The Kubes lab has grown again! A warm welcome to two new graduate students to our lab, Rachita Panda and Tina Sarkar, visiting MSc student Salie Maasewerd, and BHSc hons. student Chelsea Ford-Sahibzada!