Publications

2024

Structural and quantum chemical basis for OCP-mediated quenching of phycobilisomes

Sauer P V, Cupellini L, Sutter M, Bondanza M, Martin MAD, Kirst H, Bína D, Koh AF, Kotecha A, Greber BJ, et al (2024) Structural and quantum chemical basis for OCP-mediated quenching of phycobilisomes. Sci Adv 10: eadk7535

2023

Heterologous Assembly of Pleomorphic Bacterial Microcompartment Shell Architectures Spanning the Nano- to Microscale

Kirst H*, Ferlez BH*, Greber BJ, Nogales E, Sutter M, Kerfeld CA (2023). Adv Mater https://doi.org/10.1002/adma.202212065 (* co-first authors)

2022

Structures of a phycobilisome in light-harvesting and photoprotected states

Dominguez-Martin MA*, Sauer PV*, Kirst H, Sutter M, Bina D, Greber BJ, Nogales E, Polívka T, Kerfeld CA (2022). Nature 609:835–845 (* co-first authors)

Construction of a synthetic bacterial organelle containing a glycyl radical enzyme to produce pyruvate from formate and acetate

Kirst H, Ferlez BH, Lindner S, Cotton CAR, Bar-Even A, Kerfeld CA (2022). PNAS 119 (8) e2116871119

2021

Validation of an insertion-engineered isoprene synthase as a strategy to improve terpene synthases

Gonzalez-Esquer CR, Ferlez BH, Wijetilleke S, Kirst H, Lantz AT, Turmo A, Kerfeld CA, Sharkey TD (2021). RCS Adv 11:29997

Clues to the Function of Bacterial Microcompartments from Ancillary Genes

Kirst H, Kerfeld CA (2021). Biochem Soc Trans 49: 1085–1098

2019

Bacterial microcompartments: catalysis-enhancing metabolic modules for next generation metabolic and biomedical engineering

Kirst H and Kerfeld CA (2019). BMC biology 17:79-90

Loss of ALBINO3b insertase results in truncated light-harvesting antenna in diatoms

Nymark M, Volpe C, Hafskjold MCG, Kirst H, Serif M, Vadstein O, Bones AM, Melis A, Winge P (2019). Plant Physiol 181:1257-1276

Heterohexamers Formed by CcmK3 and CcmK4 Increase the Complexity of Beta Carboxysome Shells

Sommer M, Sutter M, Gupta S, Kirst H, et al (2019). Plant Physiol 179:156–167

2018

Downregulation of the CpSRP43 gene expression confers a Truncated Light-harvesting Antenna (TLA) and enhances biomass and leaf-to-stem ratio in Nicotiana tabacum canopies

Kirst H, Shen Y, Vamvaka E, Betterle N, Xu D, Warek U, Strickland JA, Melis A (2018). Planta 248:139-154

Improving photosynthetic energy conversion efficiency: The Truncated Light-harvesting Antenna (TLA) concept. Chapter 14 in Microalgal Hydrogen Production: Achievements and Perspectives

Kirst H and Melis A (2018). Seibert M, Torzillo G, Eds. European Society for Photobiology 2018. Published by the Royal Society of Chemistry, London. Pp. 335-353

2017

Deletion of the chloroplast LTD protein impedes LHCI import and PSI–LHCI assembly in Chlamydomonas reinhardtii

Jeong J, Baek K, Yu J, Kirst H, Betterle N, Shin W, Bae S, Melis A, Jin E (2017). J Exp Bot erx457

Engineering Isoprene Synthase Expression and Activity in Cyanobacteria

Chaves JE, Rueda-Romero P, Kirst H, Melis A (2017). ACS Synthetic Biology 6:2281-2292

Photosynthetic antenna engineering to improve crop yields

Kirst H, Gabilly S, Niyogi KK, Lemaux PG, Melis A (2017). Planta 245:1009-1020

Loss of CpSRP54 function leads to a truncated light-harvesting antenna size in Chlamydomonas reinhardtii

Jeong J, Baek K, Kirst H, Melis A, Jin E (2017). Biochim Biophys Acta 1858:45-55

2016

Role of isopentenyl-diphosphate isomerase in heterologous cyanobacterial (Synechocystis) isoprene production

Chaves JE, Kirst H, Melis A (2016). Photosynth Res 130:517-527

2015

Isoprene production in Synechocystis under alkaline and saline growth conditions

Chaves JE, Kirst H, Melis A (2015). J Appl Phycol 27:1089–1097

2014

Maximizing photosynthetic efficiency and culture productivity in cyanobacteria upon minimizing the phycobilisome light-harvesting antenna size

Kirst H, Formighieri C, Melis A (2014). BBA-Bioenergetics 1837:1653-1664.

The chloroplast Signal Recognition Particle pathway (CpSRP) as a tool minimize chlorophyll antenna size and maximize photosynthetic productivity

Kirst H and Melis A (2014). Biotechnol Adv 32:66-72

2012

Truncated photosystem chlorophyll antenna size in the green microalga Chlamydomonas reinhardtii upon deletion of the TLA3-CpSRP43 gene

Kirst H, Garcia‐Cerdán JG, Zurbriggen A, Rühle T, Melis A (2012). Plant Physiol 160:2251–2260.

Modulation of the light-harvesting chlorophyll antenna size in Chlamydomonas reinhardtii by TLA1 gene over-expression and RNA interference

Mitra M, Kirst H, Dewez D, Melis A (2012). Phil Trans R Soc B 367:3430-3443.

Isoprene production via the mevalonic acid pathway in Escherichia coli (bacteria)

Zurbriggen A, Kirst H, Melis A (2012) . Bioenergy Res 5:814–828.

Assembly of the light‐harvesting chlorophyll antenna in the green alga Chlamydomonas reinhardtii requires expression of the TLA2‐CpFTSY gene

Kirst H, Garcia‐Cerdán JG, Zurbriggen A, Melis A (2012). Plant Physiol 158:930-945.