Publications

Huntington Medcial Research Institutes:

Mohammed Abdul KS, Powell J, Munoz C, Retana G and Purcell NH. Oxidative stress drives PHLPP1 degradation through the Ubiquitin Proteosome System in the heart. 2025, under preparation.

Mohammed Abdul KS, Stienhans I, Santos SG, Rausch H, Purcell NH. Recent advances in PHLPP1 and PHLPP2 research: an update in the heart. Current Opinion in Physiology, 2025 Oct, in press

Santos SG, Mohammed Abdul KS, Purcell NH. Protein Phosphatases in Metabolic Dysfunction-Associated Steatotic Liver Disease: Emerging Mechanisms and Therapeutic Strategies. Current Opinion in Physiology, 2025 Sep, 46:100860. 

Mohammed Abdul KS, Han K, Guerrero AB, Wilson CN, Kulkarni A, Purcell NH. Increased PHLPP1 expression through ERK-4E-BP1 signaling axis drives nicotine induced oxidative stress related damage of cardiomyocytes. J Mol Cell Cardiol. 2024 Aug;193:100-112. doi: 10.1016/j.yjmcc.2024.05.014. Epub 2024 Jun 6. PubMed PMID: 38851627.

Guangdong University of Technology:

Mohammed Abdul KS, Faiz N, Jovanović A, Tan W. Isosteviol Protects H9c2 Cells Against Hypoxia-reoxygenation by Activating ERK1/2. Cardiovasc Hematol Disord Drug Targets. 2021;21(1):73-77. doi: 10.2174/1871529X21666210216122022. PubMed PMID: 33593268.

Mohammed Abdul KS, Rayadurgam J, Faiz N, Jovanović A, Tan W. Cardioprotection by isosteviol derivate JC105: A unique drug property to activate ERK1/2 only when cells are exposed to hypoxia-reoxygenation. J Cell Mol Med. 2020 Sep;24(18):10924-10934. doi: 10.1111/jcmm.15721. Epub 2020 Aug 14. PubMed PMID: 32794652; PubMed Central PMCID: PMC7521240.

Zhang R, Hu J, Deng L, Li S, Chen X, Liu F, Wang S, Mohammed Abdul KS, Beng H, Tan W.Aerosol Characteristics and Physico-Chemical Compatibility of Combivent(®) (Containing Salbutamol and Ipratropium Bromide) Mixed with Three Other Inhalants: Budesonide, Beclomethasone or N-Acetylcysteine. Pharmaceutics. 2020 Jan 17;12(1). doi: 10.3390/pharmaceutics12010078. PubMed PMID: 31963493; PubMed Central PMCID: PMC7023084.

Zhang X, Lu Z, Mohammed Abdul KS, Changping MA, Tan KS, Jovanovi A, Tan W. Isosteviol sodium protects heart embryonic H9c2 cells against oxidative stress by activating Akt/GSK-3β signaling pathway.Pharmazie. 2020 Jan 2;75(1):36-40. doi: 10.1691/ph.2020.9851. PubMed PMID: 32033632.

University of Ruhuna:

Mohammed Abdul KS, De Silva PMCS, Ekanayake EMDV, Thakshila WAKG, Gunarathna SD, Gunasekara TDKSC, Jayasinghe SS, Asanthi HB, Chandana EPS, Chaminda GGT, Siribaddana SH, Jayasundara N. Occupational Paraquat and Glyphosate Exposure May Decline Renal Functions among Rural Farming Communities in Sri Lanka. Int J Environ Res Public Health. 2021 Mar 22;18(6). doi: 10.3390/ijerph18063278. PubMed PMID: 33810013; PubMed Central PMCID: PMC8005187.

De Silva PM, Mohammed Abdul KS, Eakanayake EM, Jayasinghe SS, Jayasumana C, Asanthi HB, Perera HS, Chaminda GG, Chandana EP, Siribaddana SH. Urinary Biomarkers KIM-1 and NGAL for Detection of Chronic Kidney Disease of Uncertain Etiology (CKDu) among Agricultural Communities in Sri Lanka. PLoS Negl Trop Dis. 2016 Sep;10(9):e0004979. doi: 10.1371/journal.pntd.0004979. eCollection 2016 Sep. PubMed PMID: 27643785; PubMed Central PMCID: PMC5028052.

Mohammed Abdul KS, Jayasinghe SS, Chandana EP, Jayasumana C, De Silva PM. Arsenic and human health effects: A review. Environ Toxicol Pharmacol. 2015 Nov;40(3):828-46. doi: 10.1016/j.etap.2015.09.016. Epub 2015 Sep 30. Review. PubMed PMID: 26476885.

University of Dundee:

Mohammed Abdul KS, Jovanović S, Jovanović A. Exposure to 15% oxygen in vivo up-regulates cardioprotective SUR2A without affecting ERK1/2 and AKT: a crucial role for AMPK. J Cell Mol Med. 2017 Jul;21(7):1342-1350. doi: 10.1111/jcmm.13064. Epub 2017 Jan 25. PubMed PMID: 28121062; PubMed Central PMCID: PMC5487919.

Mohammed Abdul KS, Jovanović S, Du Q, Sukhodub A, Jovanović A. Mild hypoxia in vivo regulates cardioprotective SUR2A: A role for Akt and LDH. Biochim Biophys Acta. 2015 May;1852(5):709-19. doi: 10.1016/j.bbadis.2015.01.001. Epub 2015 Jan 8. PubMed PMID: 25576887; PubMed Central PMCID: PMC4547089.

Mohammed Abdul KS, Jovanović S, Du Q, Sukhodub A, Jovanović A. A link between ATP and SUR2A: A novel mechanism explaining cardioprotection at high altitude. Int J Cardiol.2015;189:73-6. doi: 10.1016/j.ijcard.2015.04.069. Epub 2015 Apr 11. Review. PubMed PMID: 25885875; PubMed Central PMCID: PMC4461008.

Mohammed Abdul KS, Jovanović S, Sukhodub A, Du Q, Jovanović A. Upregulation of cardioprotective SUR2A by sub-hypoxic drop in oxygen. Biochim Biophys Acta. 2014 Nov;1843(11):2424-31. doi: 10.1016/j.bbamcr.2014.07.007. Epub 2014 Jul 23. PubMed PMID: 25064694; PubMed Central PMCID: PMC4331663.

Du Q, Jovanović S, Tulić L, Sljivančanin D, Jack DW, Zižić V, Mohammed Abdul KS, Tulić I, Jovanović A. KATP channels are up-regulated with increasing age in human myometrium. Mech Ageing Dev. 2013 Mar;134(3-4):98-102. doi: 10.1016/j.mad.2013.01.003. Epub 2013 Jan 28. PubMed PMID: 23369859.