Discovering the molecular-level mechanisms for the formation of biomolecular condensates
Deciphering the role of biomolecular condensates in genome organization
Elucidating the molecular determinants of biomolecular condensate structural and dynamical properties
Unraveling the molecular-level signatures of condensates prone to aggregation, aging, and its link to diseases
Manipulating of phase behavior to design biomaterials
Designing small molecules for condensate-linked diseases
Identification of suitable building blocks, controlling assembly pathways, developing physics-constrained inverse design strategy
Integrating experimental data to build, validate, and interrogate/improve atomistic and coarse-grained computational models
Accurate prediction of structural and thermophysical properties, and phase behavior