Zheng B, Ko KP, Fang X, Wang X, Zhang J, Jun S, Kim BJ, Luo W, Kim MJ, Jung YS, Cervantes CL, Park JI. A new murine esophageal organoid culture method and organoid-based model of esophageal squamous cell neoplasia. iScience. 2021 Nov 15;24(12):103440. doi: 10.1016/j.isci.2021.103440.
Wi DH, Cha JH, Jung YS. Mucin in cancer: a stealth cloak for cancer cells. BMB Reports. 2021 Jul;54(7):344-355. doi: 10.5483/BMBRep.2021.54.7.064. (Invited Review Paper)
Kim MJ, Cervantes CL, Jung YS, Zhang X, Zhang J, Lee SH, Jun S, Litovchick L, Wang W, Chen J, Fang B, Park JI. PAF remodels the DREAM complex to bypass cell quiescence and promote lung tumorigenesis. Molecular Cell. 2021 Apr 15;81(8):1698-1714.e6. doi: 10.1016/j.molcel.2021.02.001. Epub 2021 Feb 23.
Jung YS, Stratton AS, Lee SH, Kim MJ, Jun S, Zhang J, Zheng B, Cervantes CL, Cha JH, Barton MC, Park JI. TMEM9-v-ATPase Activates Wnt/β-Catenin Signaling via APC Lysosomal Degradation for Liver Regeneration and Tumorigenesis. Hepatology. 2021 Feb;73(2):776-794. doi: 10.1002/hep.31305.
Kim HK, Bae J, Lee SH, Hwang SH, Kim MS, Kim MJ, Jun S, Cervantes CL, Jung YS, Back S, Lee H, Lee SE, Dougherty PM, Lee SW, Park JI, Abdi S. Blockers of Wnt3a, Wnt10a, or β-Catenin Prevent Chemotherapy-Induced Neuropathic Pain In Vivo. Neurotherapeutics. 2021 Jan;18(1):601-614. doi: 10.1007/s13311-020-00956-w. Epub 2020 Oct 30.
Kim K, Yang WH, Jung YS, Cha JH. A new aspect of an old friend: the beneficial effect of metformin on anti-tumor immunity. BMB Reports. 2020 Nov;53(10):512-520. doi: 10.5483/BMBRep.2020.53.10.149. (Review Paper)
Jung YS and Park JI. Wnt signaling in cancer: therapeutic targeting of Wnt signaling beyond β-catenin and the destruction complex. Experimental & Molecular Medicine. 2020 Feb;52(2):183-191. doi: 10.1038/s12276-020-0380-6. Epub 2020 Feb 10. (Invited Review Paper)
Jung YS*, Kim MJ*, Park JI. LncGata6-controlled stemness in regeneration and cancer. Noncoding RNA Investigation. 2019 Jan;3. pii: 4. doi: 10.21037/ncri.2019.01.02. Epub 2019 Jan 15. (Invited Review Paper) *Co-first authors
Jung YS*, Jun S*, Kim MJ, Lee SH, Suh HN, Lien EM, Jung HY, Lee S, Zhang J, Yang JI, Ji H, Wu JY, Wang W, Miller RK, Chen J, McCrea PD, Kopetz S, Park JI. TMEM9 promotes intestinal tumorigenesis through vacuolar-ATPase-activated Wnt/β-catenin signalling. Nature Cell Biology. 2018 Dec;20(12):1421-1433. doi: 10.1038/s41556-018-0219-8. Epub 2018 Oct 29. *Co-first authors
Jung YS, Wang W, Jun S, Zhang J, Srivastava M, Kim MJ, Lien EM, Shang J, Chen J, McCrea PD, Zhang S, Park JI. Deregulation of CRAD-controlled cytoskeleton initiates mucinous colorectal cancer via β-catenin. Nature Cell Biology. 2018 Nov;20(11):1303-1314. doi: 10.1038/s41556-018-0215-z. Epub 2018 Oct 22.
Suh HN, Kim MJ, Jung YS, Lien EM, Jun S, Park JI. Quiescence Exit of Tert+ Stem Cells by Wnt/β-Catenin Is Indispensable for Intestinal Regeneration. Cell Reports. 2017 Nov 28;21(9):2571-2584. doi: 10.1016/j.celrep.2017.10.118.
Lee SJ*, Jung YS*, Yoon MH, Kang SM, Oh AY, Lee JH, Jun SY, Woo TG, Chun HY, Kim SK, Chung KJ, Lee HY, Lee K, Kim G, Na MK, Ha NC, Bárcena C, Freije JM, López-Otín C, Song GY, Park BJ. Interruption of progerin-lamin A/C binding ameliorates Hutchinson-Gilford progeria syndrome phenotype. Journal of Clinical Investigation. 2016 Oct 3;126(10):3879-3893. doi: 10.1172/JCI84164. *Co-first authors
Oh AY*, Jung YS*, Kim J*, Lee JH, Cho JH, Chun HY, Park S, Park H, Lim S, Ha NC, Park JS, Park CS, Song GY, Park BJ. Inhibiting DX2-p14/ARF interaction exerts antitumor effects in lung cancer and delays tumor progression. Cancer Research. 2016 Aug 15;76(16):4791-804. doi: 10.1158/0008-5472.CAN-15-1025 *Co-first authors
Cho JH, Chun HY, Lee JS, Lee JH, Cheong KJ, Jung YS, Woo TG, Yoon MH, Oh AY, Kang SM, Lee C, Sun H, Hwang J, Song GY, Park BJ. Prevention effect of rare ginsenosides against stress-hormone induced MTOC amplification. Oncotarget. 2016 Apr 27. doi: 10.18632/oncotarget.9059.
Jun S, Jung YS, Suh HN, Wang W, Kim MJ, Oh YS, Lien EM, Shen X, Matsumoto Y, McCrea PD, Li L, Chen J, Park JI. LIG4 mediates Wnt signalling-induced radioresistance. Nature Communications. 2016 Mar 24;7:10994. doi: 10.1038/ncomms10994.
Wang X*, Jung YS*, Jun S*, Lee S, Wang W, Schneider A, Sun Oh Y, Lin SH, Park BJ, Chen J, Keyomarsi K, Park JI. PAF-Wnt signaling-induced cell plasticity is required for maintenance of breast cancer cell stemness. Nature Communications. 2016 Feb 4;7:10633. doi: 10.1038/ncomms10633. *Co-first authors
Jung YS, Jun S, Lee SH, Sharma A, Park JI. Wnt2 complements Wnt/β-catenin signaling in colorectal cancer. Oncotarget. 2015 Nov 10;6(35):37257-68. doi: 10.18632/oncotarget.6133.
Kim JS, Ku B, Woo TG, Oh AY, Jung YS, Soh YM, Yeom JH, Lee K, Park BJ, Oh BH, Ha NC. Conversion of cell-survival activity of Akt into apoptotic death of cancer cells by two mutations on the BIM BH3 domain. Cell Death & Disease. 2015 Jul 2;6:e1804. doi: 10.1038/cddis.2015.118.
Jung YS, Chun HY, Yoon MH, Park BJ. Elevated estrogen receptor-α in VHL-deficient condition induces microtubule organizing center amplification via disruption of BRCA1/Rad51 interaction. Neoplasia. 2014 Dec;16(12):1070-81. doi: 10.1016/j.neo.2014.09.013.
Jung YS*, Lee SJ*, Lee SH, Chung JY, Jung YJ, Hwang SH, Ha NC, Park BJ. Loss of VHL promotes progerin expression, leading to impaired p14/ARF function and suppression of p53 activity. Cell Cycle. 2013 Jul 15;12(14):2277-90. *Co-first authors
Chung JY, Park HR, Lee SJ, Lee SH, Kim JS, Jung YS, Hwang SH, Ha NC, Seol WG, Lee J, Park BJ. Elevated TRAF2/6 expression in Parkinson's disease is caused by the loss of Parkin E3 ligase activity. Laboratory Investigation. 2013 Jun;93(6):663-76.
Jung YS, Lee SJ, Yoon MH, Ha NC, Park BJ. Estrogen receptor α is a novel target of the Von Hippel-Lindau protein and is responsible for the proliferation of VHL-deficient cells under hypoxic conditions. Cell Cycle. 2012 Dec 1;11(23):4462-73.
Lee SH, Jung YS, Chung JY, Oh AY, Lee SJ, Choi DH, Jang SM, Jang KS, Paik SS, Ha NC, Park BJ. Novel tumor suppressive function of Smad4 in serum starvation-induced cell death through PAK1-PUMA pathway. Cell Death & Disease. 2011 Dec 1;2:e235.
Chung JY, Lee SJ, Lee SH, Jung YS, Ha NC, Seol W, Park BJ. Direct interaction of α-synuclein and AKT regulates IGF-1 signaling: implication of Parkinson disease. Neurosignals. 2011;19(2):86-96.
Lee SH, Shen GN, Jung YS, Lee SJ, Chung JY, Kim HS, Xu Y, Choi Y, Lee JW, Ha NC, Song GY, Park BJ. Antitumor effect of novel small chemical inhibitors of Snail-p53 binding in K-Ras-mutated cancer cells. Oncogene. 2010 Aug 12;29(32):4576-87.
Xu Y, Lee SH, Kim HS, Kim NH, Piao S, Park SH, Jung YS, Yook JI, Park BJ, Ha NC. Role of CK1 in GSK3beta-mediated phosphorylation and degradation of snail. Oncogene. 2010 May 27;29(21):3124-33.
Lee SJ, Jung YS, Lee SH, Chung HY, Park BJ. Isolation of a chemical inhibitor against K-Ras-induced p53 suppression through natural compound screening. International Journal of Oncology. 2009 Jun;34(6):1637-43.
Lee SH, Lee SJ, Chung JY, Jung YS, Choi SY, Hwang SH, Choi D, Ha NC, Park BJ. p53, secreted by K-Ras-Snail pathway, is endocytosed by K-Ras-mutated cells; implication of target-specific drug delivery and early diagnostic marker. Oncogene. 2009 May 14;28(19):2005-14.
Lee SH, Lee SJ, Jung YS, Xu Y, Kang HS, Ha NC, Park BJ. Blocking of p53-Snail binding, promoted by oncogenic K-Ras, recovers p53 expression and function. Neoplasia. 2009 Jan;11(1):22-31, 6p following 31.