2022

146. Roberts AL, Morea A, Amar A, Zito A, El-Sayed Moustafa JS, Tomlinson M, Bowyer RCE, Zhang X, Christiansen C, Costeira R, Steves CJ, Mangino M, Bell JT, Wong6 CCY, Vyse TJ, Small KS. 2022. Age acquired skewed X Chromosome Inactivation is associated with adverse health outcomes in humans. eLife, 11:e78263. https://doi.org/10.7554/eLife.78263

145. Lee M, Huan T, McCartney DL, Chittoor G, de Vries M, Lahousse L, Nguyen JN, Brody JA, Castillo-Fernandez J, Terzikhan N, Qi C, Joehanes R, Min JL, Smilnak GJ, Shaw JR, Yang CX, Colicino E, Hoang TT, Bermingham ML, Xu H, Justice AE, Xu C-J, Rich SS, Cox SR, Vonk JM, Proki ́c I, Sotoodehnia N, Tsai P-C, Schwartz JD, Leung JM, Sikdar S, Walker RM, Harris SE, van der Plaat DA, Van Den Berg DJ, Bartz TM, Spector TD, Vokonas PS, Marioni RE, Taylor AM, Liu Y, Barr RG, Lange LA, Baccarelli AA, Obeidat A, Fornage M, Wang T, Ward JM, Motsinger-Reif AM, Hemani G, Koppelman GH, Bell JT, Gharib SA, Brusselle G, Boezen HM, KE North, Levy D, Evans KL, Dupuis J, Breeze CE, Manichaikul A, London SJ. 2022. Pulmonary Function and Blood DNA Methylation A Multiancestry Epigenome-Wide Association Meta-analysis. American Journal of Respiratory and Critical Care Medicine, 206(3):321-336. https://doi.org/10.1164/rccm.202108-1907OC

144. Christiansen C, Tomlinson M, Eliot M, Nilsson E, Costeira R, Xia Y, Villicana S, Mompeo O, Wells P, Castillo-Fernandez J, Potier L, Vohl M-C, Tchernof A, El-Sayed Moustafa J, Menni C, Steves CJ, Kelsey K, Ling C, Grundberg E, Small KS, Bell JT. 2022. Adipose methylome integrative-omic analyses reveal genetic and dietary metabolic health drivers and insulin resistance classifiers. Genome Medicine, 14:75. https://doi.org/10.1186/s13073-022-01077-z

143. El-Sayed Moustafa J, Jackson AU, Brotman SM, Guan L, Villicana S, Roberts AL, Zito A, Bonnycastle L, Erdos MR, Narisu N, Stringham HM, Welch R, Yan T, Lakka T, Parker S, Tuomilehto J, Seow J, Graham C, Huettner I, Acors S, Kouphou N, Wadge S, Duncan EL, Steves CJ, Doores KJ, Malim MH, Collins FS, Pajukanta P, Boehnke M, Koistinen HA, Laakso M, Falchi M, Bell JT, Scott LJ, Mohlke KL, and Small KS. 2022. ACE2 expression in adipose tissue is associated with COVID-19 cardio-metabolic risk factors and cell type composition. Int J Obesity, 46:1478–1486. https://doi.org/10.1038/s41366-022-01136-w

142. Wielscher M, Mandaviya PR, Kuehnel B, Joehanes R, Mustafa R, Robinson O, Zhang Y, Bodinier B, Walton E, Mishra PP, Schlosser P, Wilson R, Tsai P-C, Palaniswamy S, Marioni RE, Fiorito G, Cugliari G, Karhunen V, Ghanbari M, Psaty BM, Loh M, Bis JC, Lehne B, Sotoodehnia N, Deary IJ, Chadeau-Hyam1 M, Brody JA, Cardona A, Selvin E, Smith AK, Miller AH, Torres MA, Marouli E, Gào X, van Meurs JBJ, Graf-Schindler J, Rathmann W, Koenig W, Peters A, WeningerW; MattFarlik M, Zhang T, Chen W, Xia Y, Teumer A, Nauck M, Grabe HJ, Doerr M, Lehtimäki T, Guan W, Milani L, Tanaka T, Fisher K, Waite LL, Kasela S, Vineis P, Verweij N, van der Harst P, Iacoviello L, Sacerdote C, Panico S, Krogh V, Tumino R, Tzala E, Matullo G, Hurme MA, Raitakari OT, Colicino E, Baccarelli AA, Kähönen M, Herzig K-H, Li S, BIOS consortium, Conneely KN, Kooner JS, Köttgen A, Heijmans BT, Deloukas P, Relton C, Ong KK, Bell JT, Boerwinkle E, Elliott P, Brenner H, Beekman M, Levy D, Waldenberger M, Chambers JC, Dehghan A, Järvelin M-R. DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases. 2022. Nature Communications, 13:2408. https://doi.org/10.1038/s41467-022-29792-6

2021

141. Costeira R, Lee KA, Murray B, Christiansen C, Castillo-Fernandez J, Lochlainn MN, Capdevila Pujol J, Macfarlane H, Kenny LC, Buchan I, Wolf J, Rymer J, Ourselin S, Steves CJ, Spector TD, Newson LR, Bell JT. 2021. Estrogen and COVID-19 symptoms: Associations in women from the COVID Symptom Study. PLoS One, https://doi.org/10.1371/journal.pone.0257051

140. Maas SCE, Vidaki A, Teumer A, Costeira R, Wilson R, van Dongen J, Beekman M, Völker U, Grabe HJ, Kunze S, Ladwig K-H, van Meurs JBJ, Uitterlinden AG, Voortman T, Boomsma DI, Slagboom PE, van Heemst D, van der Kallen CJH, van den Berg LH, Waldenberger M, Völzke H, Peters A, Bell JT, Ikram MA, Ghanbari M and Kayser M. 2021. Validating biomarkers and models for epigenetic inference of alcohol consumption from blood. Clinical Epigenetics, 13:198. https://doi.org/10.1186/s13148-021-01186-3

139. Xia Y, Brewer A, Bell JT. 2021. DNA methylation signatures of incident coronary heart disease: findings from epigenome-wide association studies. Clinical Epigenetics, 13:186. https://doi.org/10.1186/s13148-021-01175-6

138. Min JL*, Hemani G*, Hannon E, Dekkers KF, Castillo-Fernandez J, Luijk R, Carnero-Montoro E, Lawson DJ, Burrows K, Suderman M, Bretherick AD, Richardson TG, Klughammer J, Iotchkova V, Sharp G, Al Khleifat A, Shatunov A, Iacoangeli A, McArdle WL, Ho KM, Kumar A, Söderhäll C, Soriano-Tárraga C, Giralt-Steinhauer E, Kazmi N, Mason D, McRae AF, Corcoran DL, Sugden K, Kasela S, Cardona A, Day FR, Cugliari G, Viberti C, Guarrera S, Lerro M, Gupta R, Bollepalli S, Mandaviya P, Zeng Y, Clarke T-K, Walker RM, Schmoll V, Czamara D, Ruiz-Arenas C, Rezwan FI, Marioni RE, Lin T, Awaloff Y, Germain M, Aïssi D, Zwamborn R, van Eijk K, Dekker A, van Dongen J, Hottenga J-J, Willemsen G, Xu C-J, Barturen G, Català-Moll F, Kerick M, Wang C, Melton P, Elliott HR, Shin J, Bernard M, Yet I, Smart M, Gorrie-Stone T, BIOS Consortium, Shaw C, Al Chalabi A, Ring SM, Pershagen G, Melén E, Jiménez-Conde J, Roquer J, Lawlor DA, Wright J, Martin NG, Montgomery GW, Moffitt TE, Poulton R, Esko T, Milani L, Metspalu A, Perry JRB, Ong KK, Wareham NJ, Matullo G, Sacerdote C, Panico S, Caspi A, Arseneault L, Gagnon F, Ollikainen M, Kaprio J, Felix JF, Rivadeneira F, Tiemeier H, van IJzendoorn MH, Uitterlinden AG, Jaddoe VWV, Haley C, McIntosh AM, Evans KL, Murray A, Räikkönen K, Lahti J, Nohr EA, Sørensen TIA, Hansen T, Schmidt Morgen C, Binder EB, Lucae S, Ramon Gonzalez J, Mariona Bustamante M, Sunyer J, Holloway JW, Karmaus W, Zhang H, Deary IJ, Wray NR, Starr JM, Beekman M, van Heemst D, Slagboom PE, Morange P-E, Trégouët D-A, Veldink JH, Davies GE, de Geus EJC, Boomsma DI, Vonk JM, Brunekreef B, Koppelman GH, Alarcón-Riquelme ME, Huang R-C, Craig Pennell C, van Meurs J, Ikram MA, Hughes AD, Tillin T, Chaturvedi N, Pausova Z, Paus T, Spector TD, Kumari M, Schalkwyk LC, Visscher PM, Davey Smith G, Bock C, Gaunt TR, Bell JT*, Heijmans BT*, Mill J*, Relton CL*. 2021. Genomic and phenomic insights from an atlas of genetic effects on DNA methylation. Nature Genetics, 53: 1311-1321, https://doi.org/10.1038/s41588-021-00923-x

137. McCartney D, Min J, Richmond R, Lu A, Sobczyk M, Davies G, Broer L, Guo X, Jeong A, Jung J, Kasela S, Katrinli S, Kuo P, Matias-Garcia P, Mishra P, Nygard M, Palviainen T, Patki A, Raffield L, Ratliff S, Richardson T, Robinson O, Soerensen M, Sun D, Tsai P-C, van der Zee M, Walker R, Wang X, Wang Y, Xia R, Xu Z, Yao J, Zhao W, Correa A, Boerwinkle E, Dugue P-A, Durda P, Elliot H, Gieger C, de Geus E, Harris S, Hemani G, Imboden M, Kahonen M, Kardia S, Kresovich J, Li S, Lunetta K, Mangino M, Mason D, McIntosh A, Mengel-From J, Moore A, Murabito J, Ollikainen M, Pankow J, Perdesen N, Peters A, Polidoro S, Porteous D, Raitakari O, Rich S, Sandler D, Sillanpaa E, Smith A, Southey M, Strauch K, Tiwari H, Tanaka T, Tillin T, Uitterlinden A, van den Berg D, van Dongen J, Wilson J, Wright J, Yet I, Arnett A, Bandinelli S, Bell JT, Binder A, Boomsma D, Chen W, Christensen K, Conneely K, Elliot P, Ferrucci L, Fornage M, Sara Hagg S, Hayward C, Irvin M, Kaprio J, Lawlor D, Lehtimaki T, Lohoff F, Milani L, Milne R, Probst-Hensch N, Reiner A, Ritz B, Rotter J, Smith J, Taylor J, van Meurs J, Vineis P, Waldenberger M, Deary I, Relton C, Horvath S, Marioni R. Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. Genome Biology, 22:194, https://doi.org/10.1186/s13059-021-02398-9

136. Maddock J, Castillo-Fernandez J, Wong A, Ploubidis GB, Kuh D, Bell JT, Hardy R. 2021. Childhood growth and development and DNA methylation age in mid-life. Clinical Epigenetics, 13:155. https://doi.org/10.1186/s13148-021-01138-x

135. van Dongen J, Gordon SD, McRae AF, Odintsova VV, Mbarek H, Breeze CE, Sugden K, Lundgren S, Castillo-Fernandez JE, Hannon E, TE Moffitt, Hagenbeek FA, van Beijsterveldt CEM, Hottenga JJ, Tsai P-C, BIOS Consortium, The Genetics of DNA Methylation Consortium, Min J, Hemani G, Ehli EA, Paul F, Stern CD, Heijmans BT, Slagboom E, Daxinger L, van der Maarel SM, de Geus EJC, Willemsen G, Montgomery GW, Reversade B, Ollikainen M, Kaprio J, Spector TD, Bell JT, Mill J, Caspi A, Martin NG, Boomsma DI. 2021. Identical twins carry a persistent epigenetic signature of early genome programming. Nature Communications, 12:5618. https://doi.org/10.1038/s41467-021-25583-7

134. Portilla-Fernández E, Hwang S-J, Wilson R, Maddock J, Hill WD, Teumer A, Mishra PP, Brody JA, Joehanes R, Ligthart S, Ghanbari M, Kavousi M, Roks AJM, Danser AHJ, Levy D, Peters A, Ghasemi S, Schminke U, Dörr M, Grabe HJ, Lehtimäki T, Kähönen M, Hurme MA, Bartz TM, Sotoodehnia N, Bis JC, Thiery J, Koenig W, Ong KK, Bell JT, Meisinger C, Wardlaw JM, Starr JM, Seissler J, Then C, Rathmann W, Ikram MA, Psaty BM, Raitakari OT, Völzke H, Deary IJ, Wong A, Waldenberger M, O’Donnell CJ, Dehghan A. Meta-analysis of epigenome-wide association studies of carotid intima-media thickness. European Journal of Epidemiology, https://doi.org/10.1007/s10654-021-00759-z

133. Jhun MA, Mendelson M, Wilson R, Gondalia R, Joehanes R, Salfati E, Zhao E, Braun KVE, Do AN, Hedman AK, Zhang T, Carnero-Montoro E, Shen J, Bartz TM, Brody JA, Montasser ME, O’Connell JR, Yao C, Xia R, Boerwinkle E, Grove M, GuaN W, Liliane P, Singmann P, Müller-Nurasyid M, Meitinger T, Gieger C, Peters A, Zhao W, Ware EB, Smith JA, Dhana K, van Meurs J, Andre Uitterlinden A, Ikram MA, Ghanbari M, Zhi D, Gustafsson S, Lind L, Li S, Sun D, Spector TD, Chen YI, Damcott C, Shuldiner AR, Absher DM, Horvath S, Tsao PS, Kardia S, Psaty BM, Sotoodehnia N, Bell JT, Ingelsson E, Chen W, Dehghan A, Arnett D, Waldenberger M, Hou L, Whitsel EA, Baccarelli A, Levy D, Fornage M, Irvin MR, Assimes TL. A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids. Nature Communications, 12:3987. https://doi.org/10.1038/s41467-021-23899-y

132. Villicaña S and Bell JT. 2021. Genetic impacts on DNA methylation: research findings and future perspectives. Genome Biology, 22:127. https://doi.org/10.1186/s13059-021-02347-6

131. Karabegovic I, Portilla-Fernandez E, Li Y, Ma J, Maas SCE, Sun D, Hu EA, Kühnel B, Zhang Y, Ambatipudi S, Fiorito G, Huang J, Castillo-Fernandez JE, Wiggins KL, de Klein N, Grioni S, Swenson BR, Polidoro S, Treur JL, Cuenin C, Tsai P-C, Costeira R, Chajes V, Braun K, Verweij N, Kretschmer A, Franke L, van Meurs JBJ, Uitterlinden AG, de Knegt RJ, Ikram MA, Dehghan A, Peters A, Schöttker B, Gharib SA, Sotoodehnia N, Bell JT, Elliott P, Vineis P, Relton C, Herceg Z, Brenner H, Waldenberger M, Rebholz CM, Voortman T, Pan Q, Fornage M, Levy D, Kayser M, Ghanbari M. 2021. Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption. Nature Communications, 12: 2830. https://doi.org/10.1038/s41467-021-22752-6

130. Acton RJ, Yuan W, Gao F, Xia Y, Bourne E, Wozniak E, Bell J, Lillycrop C, Wang J, Dennison E, Harvey N, Mein CA, Spector TD, Hysi PG, Cooper C, Bell CG. The Genomic Loci of Specific Human tRNA Genes Exhibit Ageing-Related DNA Hypermethylation. Nature Communications, 12:2655. https://doi.org/10.1038/s41467-021-22639-6

129. Christiansen C, Castillo-Fernandez JE, Domingo-Relloso A, Zhao W, El-Sayed Moustafa JS, Tsai P-C, Maddock J, Haack K, Cole SA, Kardia SLR, Molokhia M, Suderman M, Power C, Relton C, Wong A, Kuh D, Goodman A, Small KS, Smith JA, Tellez-Plaza M, Navas-Acien A, Ploubidis GB, Hardy R, Bell JT. 2021. Novel DNA methylation signatures of tobacco smoking with trans-ethnic effects. Clinical Epigenetics, 13:36. https://doi.org/10.1186/s13148-021-01018-4

128. Kurilshikov A, Medina-Gomez C, Bacigalupe R, Radjabzadeh D, Wang J, Demirkan A, Le Roy CI, Raygoza Garay JA, Finnicum CT, Liu X, Zhernakova DV, Bonder MJ, Hansen TH, Frost F, Rühlemann MC, Turpin W, Moon J-Y, Kim H-N, Lull K, Barkan E, Shah SA, Fornage M, Szopinska-Tokov J, Wallen ZD, Borisevich D, Agreus L, Andreasson A, Bang C, Bedrani L, Bell JT, Bisgaard H, Boehnke M, Boomsma DI, Burk RD, Claringbould A, Croitoru K, Davies GE, M. van Duijn CM, Duijts L, Falony G, Fu J, van der Graaf A, Hansen T, Homuth G, Hughes DA, IJzerman RG, Jackson MA, Jaddoe VWV, Joossens M, Jørgensen T, Keszthelyi D, Knight R, Laakso M, Laudes M, Launer LJ, Lieb W, Lusis AJ, Masclee AAM, Moll HA, Mujagic Z, Qibin Q, Rothschild D, Shin H, Sørensen SJ, Steves CJ, Thorsen J, Timpson NJ, Tito RY, Vieira-Silva S, Volker U, Volzke H, Võsa U, Wade KH, Walter S, Watanabe K, Weiss S, Weiss FU, Weissbrod O, Westra H-J, Willemsen G, Payami H, Jonkers DMAE, Vasquez AA, de Geus EJC, Meyer KA, Stokholm J, Segal E, Org E, Wijmenga C, Kim H-L, Kaplan RC, Spector TD, Uitterlinden AG, Rivadeneira F, Franke A, Lerch MM, Franke L, Sanna S, D'Amato M, Pedersen O, Paterson AD, Kraaij R, Raes J, Zhernakova A. 2021. Genetics of human gut microbiome composition. Nature Genetics, 53:156–165. https://doi.org/10.1038/s41588-020-00763-1

2020

127. Do WL, Whitsel EA, Costeira R, Masachs OM, Le Roy CI, Bell JT, Staimez LR, Stein AD, Smith AK, Horvath S, Assimes TL, Liu S, Manson JE, Shadyab AH, Li Y, Hou L, Bhatti P, Jordahl K, Narayan KMV, Conneely KN. 2020. Epigenome-wide association study of diet quality in the Women’s Health Initiative and TwinsUK cohort. International Journal of Epidemiology, dyaa215. https://doi.org/10.1093/ije/dyaa215

126. Lafontaine N, Campbell PJ, Castillo-Fernandez JE, Mullin S, Mun Lim E, Joseph J, Kendrew P, Lewer M, Brown SJ, Huang R-C, Melton PE, Mori TA, Beilin LJ, Dud- bridge F, Spector TD, Wright MJ, Martin NG, McRae AF, Panicker V, Zhu G, Walsh JP, Bell JT, Wilson SG. 2020. Epigenome wide association study of thyroid function traits identifies novel associations of fT3 with KLF9 and DOT1L. The Journal of Clinical Endocrinology & Metabolism, https://doi.org/10.1210/clinem/dgaa975

125. Planterose Jim ́enez B, Liu F, Caliebe A, Montiel Gonz ́alez D, Bell JT, Kayser M, Vidaki A. 2020. Universal epigenetic inter-individual dissimilarity: Equivalent DNA methylation variation between monozygotic co-twins and unrelated individuals. Genome Biology, 22:18. DOI: 10.1186/s13059-020-02223-9

124. Reitmeier S, Kiessling S, Clavel T, List M, Almeida EL, Ghosh TS, Neuhaus K, Grallert H, Linseisen J, Skurk T, Brandl B, Breuninger TA, Troll M, Rathmann W, Linkohr B, Hauner H, Laudes M, Franke A, Le Roy CI, Bell JT, Spector T, Baumbach J, O'Toole PW, Peters A, Haller D. 2020. Arrhythmic Gut Microbiome Signatures Predict Risk of Type 2 Diabetes. Cell Host Microbe, 28(2):258-272.

123. Menni C, Zhu J, Le Roy CI, Mompeo O, Young K, Rebholz CM, Selvin E, North KE, Mohney RP, Bell JT, Boerwinkle E, Spector TD, Mangino M, Yu B, Valdes AM. 2020. Serum metabolites reflecting gut microbiome alpha diversity predict type 2 diabetes. Gut Microbes, 11:1632-1642.

122. Colicino E*, Marioni R*, Ward-Caviness C*, Gondalia R*, Guan W*, Chen B*, Tsai P-C*, Huan T*, Xu G*, Golareh A, Schwartz J, Vokonas P, Just A, Starr JM, McRae AF, Wray NR, Visscher PM, Bressler J, Zhang W, Tanaka T, Moore AZ, Pilling LC, Zhang G, Stewart JD, Li Y, Hou L, Castillo-Fernandez J, Spector T, Kiel DP, Murabito JM, Liu C, Mendelson M, Assimes T, Absher D, Tsaho PS, Lu AT, Ferrucci L, Wilson R, Waldenberger M, Prokisch H, Bandinelli S*, Bell JT*, Levy D*, Deary IJ*, Horvath S*, Pankow J*, Peters A*, Whitsel EA*, Baccarelli A*. 2020. Novel blood DNA methylation sites predict death risk in a longitudinal study of 12 300 individuals. Aging, 12:14092-14124.

121. Trejo Banos D, McCartney D, Patxot Bertran M, Anchieri L, Battram T, Christiansen C, Costeira R, Walker R, Morris S, Campbell A, Zhang Q, Porteous D, McRae A, Wray N, Visscher P, Haley C, Evans K, Deary I, Mcintosh A, Hemani G, Bell JT, Marioni R, Robinson M. 2020. Bayesian reassessment of the epigenetic architecture of complex trait. Nature Communications, 11:2865.

120. Merrick B, Robinson EJ, Bunce C, Allen L, Izundu CC, Bisnauthsing K, Bell JT, Goodman A, Shawcross D, Goldenberg S. 2020. Protocol: A prospective, randomised placebo-controlled feasibility trial of Faecal microbiota Transplant to ERadicate gastrointestinal carriage of Antibiotic Resistant Organisms (FERARO). BMJ Open, http://dx.doi.org/10.1136/bmjopen-2020-038847

119. Ryan FJ, Ahern AM, Fitzgerald RS, Laserna-Mendieta EJ, Power EM, Clooney AG, O'Donoghue KW, McMurdie PJ, Iwai S, Crits-Christoph A, Sheehan D, Moran C, Flemer B, Zomer AL, Fanning A, O'Callaghan J, Walton J, Temko A, Stack W, Jackson L, Joyce SA, Melgar S, DeSantis TZ, Bell JT, Shanahan F, Claesson MJ. 2020. Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease. Nature Communications, 11:1512.

118. Martin TC, Illieva KM, Visconti A, Beaumont M, Kiddle SJ, Dobson RJB, Mangino M, Mun Lim E, Pezer M, Steves CJ, Bell JT, Wilson SG, Lauc G, Roederer M, Walsh JP, Spector TD and Karagiannis SN. 2020. Dysregulated Antibody, Natural Killer Cell and Immune Mediator Profiles in Autoimmune Thyroid Diseases. Cells, 9:665.

117. Maddock J, Castillo-Fernandez J, Wong A, Cooper R, Richards M, Ong KK, Ploubidis GB, Goodman A, Kuh D, Bell JT, Hardy R. 2021 DNA Methylation Age and Physical and Cognitive Aging. J Gerontol A Biol Sci Med Sci, 75: 504–511, doi:10.1093/gerona/glz246

2019

116. Zito A, Davies MN, Tsai P-C, Nardone S, Bell JT, Wong CCY and Small KS. 2019. Heritability of skewed X-inactivation in female twins is tissue-specific and dependent on age. Nature Communications, 10:5539.

115. Verdi S, Abbasian G, Bowyer RCE, Lachance G, Yarand D, Christofidou P, Mangino M, Menni C, Bell JT, Falchi M, Small KS, Williams FMK, Hammond CJ, Hart DJ, Spector TD and Steves CJ. 2019. TwinsUK: The UK Adult Twin Registry Update. Twin Research and Human Genetics, 10.1017/thg.2019.65.

114. Visconti A, Le Roy CI, Rosa F, Rossi N, Martin T, Mohney R, Li W, de Rinaldis E, Bell JT, Venter J, Nelson K, Spector TD and Falchi M. 2019. Interplay between the human gut microbiome and host metabolism. Nature Communications, 10:4505.

113. Le Roy CI, Wells PM, Si J, Bowyer RE, Steves CJ, Raes J, Bell JT, Spector TD. 2019. Red Wine Consumption Associated With Increased Gut Microbiota alpha-diversity in 3 Independent Cohorts. Gastroenterology, 158:270-272.

112. Bell CG, Lowe R, Adams PD, Baccarelli AA, Beck S, Bell JT, Christensen BC, Gladyshev VN, Heijmans BT, Horvath S, Ideker T, Issa J-PJ, Kelsey KT, Marioni RE, Reik W, Relton CL, Schalkwyk LC, Teschendorff AE, Wagner W, Zhang K and Rakyan VK. 2019. DNA methylation Ageing Clocks: Challenges & Recommendations. Genome Biology, 20:249.

111. Lu AT, Seeboth A, Tsai P-C, Sun D, Quach A, Reiner AP, Kooperberg C, Ferrucci L, Hou L, Baccarelli AA, Li Y, Harris SE, Corley J, Taylor J, Deary IJ, Stewart JD, Whitsel EA, Assimes TL, Chen W, Li S, Mangino M, Bell JT, Wilson JG, Aviv A, Marioni RE, Raj K*, Horvath S*. 2019. DNA methylation-based estimator of telomere length. Aging, 11:5895.

110. Le Roy CI, Bowyer RCE, Castillo-Fernandez JE, Pallister T, Menni C, Steves CJ, Spector TD, Bell JT. 2019. Dissecting the role of the gut microbiota and diet on visceral fat mass accumulation. Scientific Reports, 9:9758.

109. Liu J, Carnero-Montoro E, van Dongen J, Lent S, Nedeljkovic I, Ligthart S, Tsai P-C, Martin T-C, Mandaviya PR, Jansen R, Peters MJ, Duijts L, Jaddoe VWV, Tiemeier H, Felix JF, Chu AY, Levy D, Hwang S-J, Bressler J, Gondalia R, Salfati EL, Herder C, Hidalgo BA, Tanaka T, Zenobia Moore A, Lemaitre RN, Jhun MA, Smith JA, Sotoodehnia N, Bandinelli S, Ferrucci L, Arnett DK, Grallert H, Assimes TL, Hou L, Baccarelli A, Whitsel EA, van Dijk KW, Amin N, Uitterlinden AG, Sijbrands EJG, Franco OH, Dehghan A, Spector TD, Dupuis J, Hivert M-F, Rotter JI, Meigs JB, Pankow JS, van Meurs JBJ, Isaacs A, Boomsma DI, Bell JT, Demirkan A and van Duijn CM. 2019. An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis. Nature Communications, 10:2581.

108. Kurushima Y, Tsai P-C, Castillo-Fernandez J, Couto Alves A, El-Sayed Moustafa JS, Le Roy C, Spector TD, Ide M, Hughes FJ, Small KS, Steves CJ, Bell JT. 2019. Epigenetic findings in periodontitis in UK twins: a cross sectional study. Clinical Epigenetics, 11:27. Link

107. Moreno-Gallego JL, Chou S-P, Di Rienzi SC, Goodrich JK, Spector T, Bell JT, Youngblut N, Hewson I, Reyes A, and Ley R. 2019. Virome Diversity Correlates with Intestinal Microbiome Diversity in Adult Monozygotic Twins. Cell Host & Microbe, 25:261-272.

106. Mandaviya PR*, Joehanes R*, Brody J*, Castillo-Fernandez JE*, Dekkers KF*, Do AN*, Graff M*, Hänninen IK*, Tanaka T*, de Jonge EAL, Kiefte-de Jong JC, Absher DM, Aslibekyan S, de Rijke YB, Fornage M, Hernandez DG, Hurme MA, Ikram MA, Jacques PF, Justice AE, Kiel DP, Lemaitre RN, Mendelson MM, Mikkilä V, Moore AZ, Pallister T, Raitakari OT, Schalkwijk CG, Sha J, Slagboom EPE, Smith CE, Stehouwer CDA, Tsai P-C, Uitterlinden AG, van der Kallen CJH, van Heemst D, Arnett DK*, Bandinelli S*, Bell JT*, Heijmans BT*, Lehtimäki T*, Levy D*, North KE*, Sotoodehnia N*, van Greevenbroek MMJ*, van Meurs JBJ*, Heil SG*. 2019. Association of dietary folate and vitamin B12 intake with genome-wide DNA methylation in blood; a large scale epigenome-wide association analysis in 5,841 individuals. The American Journal of Clinical Nutrition, doi: 10.1093/ajcn/nqz031.

2018

105. Verdi S, Jackson MA, Beaumont M, Bowyer RCE, Bell JT, Spector TD, Steves CJ. 2018. An Investigation Into Physical Frailty as a Link Between the Gut Microbiome and Cognitive Health. Frontiers in Aging Neuroscience, https://doi.org/10.3389/fnagi.2018.00398

104. Tsai P-C, Glastonbury CA, Eliot MN, Bollepalli S, Yet I, Castillo-Fernandez JE, Carnero-Montoro E, Hardiman T, Martin TC, Vickers A, Mangino M, Ward K, Pietilainen KH, Deloukas P, Spector TD, Vinuela A, Loucks EB, Ollikainen M, Kelsey KT, Small KS, Bell JT. 2018. Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health. Clinical Epigenetics 10:126.

103. Hwang J-Y, Lee HJ, Go MJ, Jang HB, Choi N-H, Bae JB, Castillo-Fernandez JE, Bell JT, Spector TD, Lee, H-J, Kim B-J. 2018. Genome-wide methylation analysis identifies ELOVL5 as an epigenetic biomarker for the risk of type 2 diabetes mellitus. Scientific Reports 8:14862.

102. Livshits G, Malkin I, Bowyer R, Verdi S, Bell JT, Menni C, Williams FMK, Steves CJ. 2018. Multi-OMICS Analyses of Frailty and Common Widespread Pain Suggest Involvement of Shared Neurological Pathways. Pain, doi: 10.1097/j.pain.0000000000001364.

101. Luijk R, Wu H, Ward-Caviness C, Hannon E, Carnero-Montoro E, Min J, Mandaviya P, Mei H, van der Maarel S, Jansen R, Relton C, Mill J, Waldenberger M, Bell JT, Franke L, Hoen PAC, Boomsma DI, van Duin CM, van Greevenbroek MMJ, Veldink JH, Wijmenga C, van Meurs J, Daxinger L, Slagboom PE, van Zwet EW, Heijmans BT. 2018. Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation. Nature communications 9:3738.

100. Webster AP, Plant D, Ecker S, Zufferey F, Bell JT, Feber A, Paul DS, Beck S, Barton A, Williams FMK, Worthington J. 2018. Increased DNA methylation variability in rheumatoid arthritis discordant monozygotic twins. Genome Medicine 10:64.

99. Maddock J, Wulaningsih W, Castillo Fernandez J, Ploubidis GB, Goodman A, Bell J, Kuh D, Hardy R. 2018. Associations between body size, nutrition and socioeconomic position in early life and the epigenome: A systematic review. PLoS ONE 13(8):e0201672.

98. Pasman J, Verweij K, Gerring Z, Stringer S, Sanchez-Roige S, Treur J, Abdellaoui A, Nivard MG, Baselmans B, Ong JS, Ip H, van der Zee M, Bartels M, Day F, Fontanillas P, Elson S, The 23andMe Research Team, de Wit H, Davis L, MacKillop J, The Substance Use Disorders Working Group of the Psychiatric Genomics Consortium, The International Cannabis Consortium, Derringer J, Branje S, Hartman C, Heath A, van Lier P, Madden P, Mägi R, Meeus R, Montgomery G, Oldehinkel A, Pausova Z, Ramos-Quiroga J, Paus T, Ribases M, Kaprio J, Boks M, Bell JT, Spector TD, Gelernter J, Boomsma DI, Martin N, Macgregor S, Perry J, Palmer A, Posthuma D, Munafo M, Gillespie N, Derks E, Vink J. 2018. GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia. Nature Neuroscience 21(9):1161-1170.

97. Jackson MA, Verdi S, Maxan M-E, Shin CM, Zierer J, Bowyer R, Martin T, Williams FMK, Menni C, Bell JT, Spector TD, and Steves CJ. 2018. Gut microbiota associations with common diseases and prescription medications in a population-based cohort. Nature Communications 9:2655.

96. Wang J, Kurilshikov A, Radjabzadeh D, Turpin W, Croitoru K, Bonder MJ, Jackson MA, Medina-Gomez C, Frost F, Homuth G, Rühlemann M, Hughes D, Kim HN; MiBioGen Consortium Initiative, Spector TD, Bell JT, Steves CJ, Timpson N, Franke A, Wijmenga C, Meyer K, Kacprowski T, Franke L, Paterson AD, Raes J, Kraaij R, Zhernakova A. 2018. Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative. Microbiome 6:101.

95. Zierer J, Jackson MA, Kastenmüller G, Mangino M, Long T, Telenti A, Mohney RP, Small KS, Bell JT, Steves CJ, Valdes AM, Spector TD, Menni C. 2018. The fecal metabolome as a functional readout of the gut microbiome. Nature Genetics 50:790-795.

94. Vidaki A, Kalamara V, Carnero-Montoro E, Spector TD, Bell JT, Kayser M. 2018. Investigating the epigenetic discrimination of identical twins using buccal swabs, saliva and cigarette butts in the forensic setting. Genes 9(5) pii: E252.

93. Small KS*, Todorcevic M*, Civelek M*, El-Sayed Moustafa JS*, Wang X*, Simon MM, Fernandez-Tajes J, Mahajan A, Horikoshi M, Hugill A, Glastonbury CA, Quaye L, Neville MJ, Sethi S, Yon M, Pan C, Che N, Vinuela A, Tsai P-C, Nag A, Buil A, Thorleifsson G, Raghavan A, Ding Q, Morris A, Bell JT, Thorsteinsdottir U, Stefansson K, Laakso M, Dahlman I, Arner P, Gloyn AL, Musunuru K*, Lusis AJ*, Cox R*, Karpe F*, McCarthy MI*. 2018. Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition. Nature Genetics 50:572-580.

92. Jackson MA, Bonder MJ, Kuncheva Z, Zierer J, Fu J, Kurilshikov A, Wijmenga C, Zhernakova A, Bell JT, Spector TD, Steves CJ. 2018. Detection of stable community structures within gut microbiota co-occurrence networks from different human populations. PeerJ 6:e4303.

91. Zaghlool SB, Mook-Kanamori DO, Kader S, Stefan N, Halama A, Engelke R, Sarwath H, Al-Dous EK, Mohamoud YA, Roemisch-Margl WA, Adamski J, Kastenmüller G, Friedrich N, Visconti A, Falchi M, Spector T, Bell J, Tsai P-C, Maija Pezer M, Lauc G, Graumann J, Malek JA, Suhre K. Linking the methylome to the phenome: a multi-omics view of the epigenetic response to complex disease and environmental insult. Human Molecular Genetics, 27: 1106-1121.

90. Lu A*, Xue L*, Salfati E, Chen B, Ferrucci L, Levy D, Joehanes R, Murabito J, Kiel D, Tsai P-C, Yet I, Bell J, Mangino M, Tanaka T, McRae A, Marioni R, Visscher P, Wray N, Deary I, Levine M, Quach A, Assimes T, Tsao P, Absher D, Stewart J, Li Y, Reiner A, Hou L, Baccarelli A, Whitsel E, Aviv A, Cardona A, Day F, Wareham N, Perry J, Ong K*, Raj K*, Lunetta K*, and Horvath S*. 2018. GWAS of epigenetic ageing rates in blood reveals a critical role for TERT. Nature communications, 9:387.

89. Bell CG, Gao F, Yuan W, Roos L, Acton RJ, Xia Y, Bell J, Ward K, Mangino M, Hysi PG, Wang J, Spector TD. 2017. Obligatory and facilitative allelic variation in the DNA methylome within common disease-associated loci. Nature Communications, 9:1.

88. Marioni RE, McRae AF, Bressler J, Colicino E, Hannon E, Li S, Prada D, Smith JA, Trevisi L, Tsai P-C, Vojinovic D, Simino J, Levy D, Liu C, Mendelson M, Satizabal CL, Yang Q, Jhun MA, Kardia SLR, Zhao W, Bandinelli S, Ferrucci L, Hernandez DG, Singleton, Harris SE, Starr JM, Kiel DP, McLean RR, Just AC, Schwartz J, Spiro A, Vokonas P, Amin N, Arfan Ikram M, Uitterlinden A, van Meurs J, Spector TD, Steves CJ, Baccarelli AA, Bell JT, van Duijn C, Fornage M, Hsu Y-H, Mill J, Mosley TH, Seshadri S, and Deary I. 2017. Meta-analysis of epigenome-wide association studies of cognitive abilities. Molecular Psychiatry, doi: 10.1038/s41380-017-0008-y.

2017

87. Vinuela A, Brown AA, Buil AA, Tsai P-C, Davies MN, Bell JT, Dermitzakis ET, Spector TD, Small KS. 2017. Age-dependent changes in mean and variance of gene expression across tissues in a twin cohort. Human Molecular Genetics, doi: 10.1093/hmg/ddx424.

86. Wahl A, Kasela S, Carnero-Montoro E, van Iterson M, Stambuk J, Sharma S, van den Akker E, Klaric L, Benedetti E, Razdorov G, Trbojevic-Akmacic I, Vuckovic F, Ugrina I, Beekman M, Deelen J, van Heemst D, Heijmans BT, BIOS Consortium, Wuhrer M, Plomp R, Keser T, Simurina M, Pavic T, Gudelj I, Kristic J, Grallert H, Kunze S, Peters A, Bell JT, Spector TD, Milani L, Slagboom PE, Lauc G, Gieger C. 2017. IgG Glycosylation and DNA Methylation Are Interconnected with Smoking. Biochim Biophys Acta, 1862:637-648.

85. Vidaki A, Diez Lopez C, Carnero-Montoro E, Ralfa A, Ward K, Spector TD, Bell JT*, Kayser M*. 2017. Epigenetic discrimination of identical twins from blood under the forensic scenario. Forensic Science International: Genetics, 31:67-80. doi: 10.1016/j.fsigen.2017.07.014

84. Richard MA, Huan T, Ligthart S, Gondalia R, Jhun MA, Brody JA, Irvin MR, Marioni R, Shen J, Tsai P-C, Montasser ME, Jia Y, Syme C, Salfati EL, Boerwinkle E, Guan W, Mosley Jr TH, Bressler J, Morrison AC, Liu C, Mendelson MM, Uitterlinden AG, van Meurs JB, BIOS Consortium, Franco OH, Zhang G, Yun Li Y, Stewart JD, Bis JC, Psaty BM, Chen Y-DI, Kardia SLR, Zhao W, Turner ST, Absher D, Aslibekyan S, Starr JM, McRae AF, Hou L, Just AC, Schwartz JD, Vokonas PS, Menni C, Spector TD, Shuldiner A, Damcott CM, Rotter JI, Palmas W, Liu Y, Paus T, Horvath S, O'Connell JR, Guo X, Pausova Z, Assimes,TL, Sotoodehnia N, Smith JA, Arnett DK, Deary IJ, Baccarelli AA, Bell JT, Whitsel E, Dehghan A, Levy D, Fornage M. 2017. DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation. American Journal of Human Genetics, 101(6):888-902.

83. Le Roy CI, Beaumont M, Jackson MA, Steves CJ, Spector TD, Bell JT. 2017. Addendum: Heritable components of the human fecal microbiome are associated with visceral fat. Gut Microbes, Aug 2:1-7. doi: 10.1080/19490976.2017.1356556

82. Morris JA*, Tsai P-C*, Joehanes R*, Zheng J*, Trajanoska K*, Soerensen M*, Forgetta V, Frost M, Spector TD, Christensen K, Christiansen L, Rivadeneira F, Tobias JH, Evans DM, Kiel DP, Hsu Y-H*, Richards JB*, Bell JT*. 2017. Epigenome-wide association of DNA methylation in whole blood with bone mineral density. Journal of Bone Mineral Density, 32:1644-1650. doi: 10.1002/jbmr.3148

81. Lin BD, Carnero Montoro E, Bell JT, Boomsma DI, de Geus EJ, Jansen R, Kluft C, Mangino M, Penninx B, Spector TD, Willemsen G, Hottenga J-J. SNP heritability and effects of genetic variants for neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio. Journal of Human Genetics, 62: 979-988. doi:10.1038/jhg.2017.76

80. Livshits G, Malkin I, Freidin MB, Xia Y, Gao F, Wang J, Spector TD, MacGregor A, Bell JT, Williams FMK. 2017. Genome-wide methylation analysis of a large population sample shows neurological pathways involvement in chronic widespread musculoskeletal pain. Pain 158:1053.

79. Castillo-Fernandez JE, Loke YJ, Bass-Stringer S, Gao F, Xia Y, Wu H, Lu H, Liu Y, Wang J, Spector TD, Saffery R, Craig JM*, Bell JT*. 2017. DNA methylation changes at infertility genes in newborn twins conceived by in vitro fertilisation. Genome Medicine, 9:28. doi:10.1186/s13073-017-0413-5. Highlighted in The Conversation

78. Wahl S*, Drong A*, Lehne B*, Loh M*, Scott WR*, Kunze S, Tsai P-C, Ried JS, Zhang W, Yang Y, Tan S, Fiorito G, Franke L, Guarrera S, Kasela S, Kriebel J, Richmond RC, Adamo M, Afzal U, Ala-Korpela M, Albetti B, Ammerpohl O, Apperley JF, Beekman M, Bertazzi PA, Black SL, Blancher C, Bonder M-J, Brosch M, Carstensen-Kirberg M, De Craen AJM, Lusignan S, Dehghan A, Elkalaawy M, Fischer K, Franco O, Gaunt TR, Hampe J, Hashemi M, Isaacs A, Jenkinson A, Jha S, Kato N, Krogh V, Laffan M, Meisinger C, Meitinger T, Mok ZY, Motta V, Ng HK, Nikolakopoulou Z, Nteliopoulos G, Panico S, Pervjakova N, Prokisch H, Rathmann W, Roden M, Rota F, Rozario MA, Sandling JK, Schafmayer C, Schramm K, Siebert R, Slagboom E, Soininen P, Stolk L, Strauch K, Tai E-S, Tarantini L, Thorand B, Tigchelaar EF, Tumino R, Uitterlinden AG, van Duijn C, van Meurs JBJ, Vineis P, Wickremasinghe AR, Wijmenga C, Yang T-P, Yuan W, Zhernakova A, Batterham R, Davey Smith G, Deloukas P, Heijmans BT, Herder C, Hofman A, Lindgren CM, Milani L, van der Harst P, Peters A, Illig T, Relton CL, Waldenberger M, Jarvelin M-R, Bollati V, Soong R, Spector TD, Scott J, McCarthy MI, Elliott P, Bell JT*, Matullo G*, Gieger C*, Kooner JS*, Grallert H*, Chambers JC*. 2017. Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity. Nature, 541(7635):81-86.

77. Roos L, Sandling JK, Bell CG, Glass D, Mangino M, Spector TD, Deloukas P, Bataille V*, and Bell JT*. 2017. Higher naevus count exhibits a distinct DNA methylation signature in healthy human skin: implications for melanoma. Journal of Investigative Dermatology, 137:910. doi: 10.1016/j.jid.2016.11.029.

2016

76. Traylor M, Malik R, Nalls MA, Cotlarciuc I, Radmanesh F, Thorleifsson G, Hanscombe KB, Langefeld C, Saleheen D, Rost NS, Yet I, Spector TD, Bell JT, Hannon E, Mill J, Chauhan G, Debette S, METASTROKE, UK Young Lacunar DNA Resource, NINDS Stroke Genetics Network, Hamilton-Bruce MA, Jimenez-Conde J, Cole JW, Schmidt R, Slowik A, Lemmens R, Lindgren A, Melander O, Grewal RP, Sacco RL, Rundek T, Rexrode K, Arnett DK, Johnson JA, Benavente OR, Wasssertheil-Smoller S, Lee JM, Pulit SL, Wong Q, Rich SS, de Bakker PIW, McArdle PF, Woo D, Anderson CD, Heitsch L, Fornage M, Jern C, Stefansson K, Thorsteinsdottir U, Gretarsdottir S, Lewis CM, Sharma P, Sudlow CLM, Rothwell PM, Boncoraglio G, Thijs V, Levi C, Meschia JF, Rosand J, Kittner SJ, Mitchell BD, Dichgans M, Worrall BB, and Markus HS. 2016. Genetic Variation in a 16q24.2 locus that influences DNA methylation and expression of ZCCHC14 is associated with small vessel stroke. Annals of Neurology, accepted. doi: 10.1002/ana.24840.

75. Davenport ER, Goodrich JK, Bell JT, Spector TD, Ley RE, Clark AG. 2016. ABO antigen and secretor statuses are not associated with gut microbiota composition in 1,500 twins. BMC Genomics, 17(1):941. doi: 10.1186/s12864-016-3290-1.

74. Beaumont M, Goodrich JK, Jackson MA, Yet I, Davenport ER, Vieira-Silva S, Debelius J, Pallister T, Mangino M, Raes J, Knight R, Clark AG, Ley RE, Spector TD*, Bell JT*. 2016. Heritable components of the human fecal microbiome are associated with visceral fat. Genome Biology, 17(1):189. doi: 10.1186/s13059-016-1052-7. Highlighted in BBC CNN Reuters Time Magazine Financial Times Genome Biology Best of 2016

73. Zierer J, Pallister T, Tsai PC, Bell JT, Lauc G, Spector TD, Menni C, Kastenmuller G. 2016. Exploring the molecular basis of age-related disease comorbidities using a multi-omics graphical model. Scientific Reports, 6:37646. doi: 10.1038/srep37646.

72. Jackson MA, Bell JT, Spector TD, Steves CJ. 2016. A heritability-based comparison of methods used to cluster 16S rRNA gene sequences into operational taxonomic units. PeerJ, 4:e2341. doi: 10.7717/peerj.2341.

71. Marzi C, Holdt LM, Fiorito G, Tsai P-C, Kretschmer A, Wahl S, Guarrera S, Teupser D, Spector TD, Iacoviello L, Sacerdote C, Strauch K, Lee S, Thasler WE, Peters A, Thorand B, Wolf P, Prokisch H, Tumino R, Gieger C, Krogh V, Panico S, Bell JT, Matullo G, Waldenberger M, Grallert H, Koenig W. 2016. Epigenetic Signatures at AQP3 and SOCS3 Engage in Low-Grade Inflammation across Different Tissues. PLoS ONE, 11(11):e0166015. doi: 10.1371/journal.pone.0166015.

70. Xie H, Guo R, Zhong H, Feng Q, Lan Z, Qin B, Ward KJ, Jackson MA, Xia Y, Chen X, Chen B, Xia H, Xu C, Li F, Xu X, Yousuf Al-Aama J, Yang H, Wang J, Kristiansen K, Wang J, Steves CJ, Bell JT, Li J, Spector TD, Jia H. 2016. Shotgun Metagenomics of 250 Adult Twins Reveals Genetic and Environmental Impacts on the Gut Microbiome. Cell Systems, 3(6):572-584.e3. doi: 10.1016/j.cels.2016.10.004.

69. Liu C*, Marioni RE*, Hedman AK*, Pfeiffer L*, Tsai P-C*, Reynolds LM*, Just AC*, Duan Q*, Boer CG*, Tanaka T, Elks CE, Aslibekyan S, Brody JA, Khnel B, Herder C, Zhi D, Wang Y, Huan T, Yao C, Mendelson MM, Joehanes R, Liang L, Love S-A, Guan W, Shah S, McRae AF, Kretschmer A, Prokisch H, Strauch K, Peters A, Visscher PM, Wray NR, Guo X, Wiggins KL, Almli LM, Smith AK, Binder EB, Ressler KJ, Irvin R, Absher DM, Hernandez D, Ferrucci L, Bandinelli S, Lohman K, Ding J, Trevisi L, Gustafsson S, Sandling J, Stolk L, Uitterlinden AG, Yet I, Castillo-Fernandez J, Spector TD, Schwartz JD, Vokonas P, Lind L, Li Y, Fornage M, Arnett DK, Sotoodehnia N, Ong KK, van Meurs JBJ, Conneely KN, Baccarelli AA, Deary IJ, Bell JT, North KE*, Liu Y*, Waldenberger M*, London SJ*, Ingelsson E*, Levy D*. 2016. A DNA Methylation Biomarker of Alcohol Consumption. Molecular Psychiatry. doi: 10.1038/mp.2016.192.

68. Richardson TG, Shihab HA, Hemani G, Zheng J, Hannon E, Mill J, Carnero-Montoro E, Bell JT, Lyttleton O, McArdle WL, Ring SM, Rodriguez S, Campbell C, Smith GD, Relton CL, Timpson NJ, Gaunt TR. 2016. Collapsed methylation quantitative trait loci analysis for low frequency and rare variants. Human Molecular Genetics, 25(19):4339-4349. doi: 10.1093/hmg/ddw283

67. Bell CG, Xia Y, Yuan W, Gao F, Ward K, Roos L, Mangino M, Hysi PG, Bell J, Wang J, and Spector TD. 2016. Novel regional age-associated DNA methylation changes within human common disease-associated loci. Genome Biology, 17(1):193, doi: 10.1186/s13059-016-1051-8.

66. Chen BH*, Marioni RE*, Colicino E*, Peters MJ, Ward-Caviness CK, Tsai P-C, Roetker NS, Just AC, Demerath EW, Guan W, Bressler J, Fornage M, Studenski S, Vandiver AR, Moore AZ, Tanaka T, Kiel DP, Liang L, Vokonas P, Schwartz J, Lunetta KL, Murabito JM, Bandinelli S, Hernandez DG, Melzer D, Nalls M, Pilling L, Price TR, Singleton AR, Gieger C, Holle R, Kretschmer A, Kronenberg F, Kunze S, Linseisen J, Meisinger C, Rathmann W, Waldenberger M, Visscher PM, Shah S, Wray NR, McRae AR, Franco OH, Hofman A, Uitterlinden AG, Absher D, Assimes T, Levine ME, Lu AT, Tsao PS, Hou L, Manson JE, Carty CL, LaCroix AZ, Reiner AP, Spector TD, Feinberg AP, Levy D*, Baccarelli A*, van Meurs J*, Bell JT*, Peters P*, Deary IJ*, Pankow JS*, Ferrucci L*, Horvath S*. 2016. DNA methylation-based measures of biological age: meta-analysis predicting time to death. Aging (Albany NY). 8(9):1844-1859. doi: 10.18632/aging.101020.

65. Livshits G, Gao F, Malkin I, Needhamsen M, Xia Y, Yuan W, Bell CG, Ward K, Liu Y, Wang J*, Bell JT*, Spector TD*. 2016. Contribution of Heritability and Epigenetic Factors to Skeletal Muscle Mass Variation in United Kingdom Twins. J Clin Endocrin Metab, 101(6): 2450-2459.

64. Goodrich JK, Davenport ER, Beaumont M, Jackson MA, Knight R, Spector TD, Bell JT, Clark AG, Ley RE. 2016. Genome wide association study of the gut microbiome in UK Twins. Cell Host Microbe 19(5): 731-743. doi: 10.1016/j.chom.2016.04.017.

63. Yet I, Menni C, Shin S-Y, Mangino M, Soranzo N, Adamski J, Suhre K, Spector TD, Kastenmuller G*, Bell JT. 2016. Genetic influences on metabolite levels: a comparison across metabolomic platforms. PLoS One, 11(4): e0153672. doi: 10.1371/journal.pone.0153672.

62. Roos L, van Dongen J, Bell CG, Burri A, Deloukas P, Boomsma DI, Spector TD, Bell JT. 2016. Integrative DNA methylome analysis of pan-cancer biomarkers in cancer discordant monozygotic twin-pair. Clinical Epigenetics, 8:7.

61. Jackson MA, Jeffery IB, Beaumont M, Bell JT, Clark AG, O’Toole PW, Ley RE, Spector TD, Steves CJ. 2016. Signatures of early frailty in the gut microbiota. Genome Medicine 8:8.

60. Al Muftah WA, Al-Shafai M, Zaghlool SB, Visconti A, Tsai PC, Kumar P, Spector T, Bell J, Falchi M, Suhre K. 2016. Epigenetic associations of type 2 diabetes and BMI in an Arab population. Clinical Epigenetics, 8:13.

59. Zierer J, Kastenmller G, Suhre K, Gieger C, Codd V, Tsai P-C, Bell J, Peters A, Strauch K, Schulz H, Weidinger S, Mohney RP, Samani NJ, Spector T, Mangino M, and Menni C. 2016. Metabolomics profiling reveals novel markers for leukocyte telomere length. Aging 8:1.

2015

58. Yet I, Tsai P-C, Castillo-Fernandez J, Carnero-Montoro E, and Bell JT. Genetic and environmental impacts on DNA methylation levels in twins. Epigenomics, 8(1):105-117. doi: 10.2217/epi.15.90.

57. Jackson MA, Goodrich JK, Maxan M-E, Freedberg DE, Abrams JA, Poole AC, Sutter JL, Welter D, Ley RE, Bell JT, Spector TD, Steves CJ. 2015. Proton Pump Inhibitors alter the composition of the gut microbiota. Gut, doi: 10.1136/gutjnl-2015-310861

56. Busche S, Shao X, Caron M, Kwan T, Allum F, Cheung W, Ge B, Westfall S, Simon M-M, The Multiple Tissue Human Expression Resource, Barrett A, Bell JT, Mark I Mc- Carthy MI, Deloukas P, Blanchette M, Bourque G, Spector TD, Lathrop M, Pastinen T, Grundberg E. 2015. Population whole-genome bisulfite sequencing across two tissues highlights environment as principal source of human methylome variation. Genome Biology, 16:290.

55. Tsai P-C, van Dongen J, Tan Q, Willemsen G, Christiansen L, Boomsma DI, Spector TD, Valdes AM*, Bell JT*. DNA methylation changes in the IGF1R gene in birth weight discordant adult monozygotic twins. Twin Research and Human Genetics, 13:1-12.

54. Blekhman R, Goodrich JK, Huang K, Sun Q, Bukowski R, Bell JT, Spector TD, Keinan A, Ley RE, Gevers D, Clark AG. 2015. Host genetic variation impacts microbiome composition across human body sites. Genome Biology, 161:191. Link

53. Barrios C*, Beaumont M*, Pallister T, Villar J, Goodrich JK, Clark A, Pascual J, Ley RE, Spector TD, Bell JT, Menni C. 2015. Gut-microbiota-metabolite axis in early renal function decline. PLoS One, 10: e0134311.

52. Tsai P-C and Bell JT. 2015. Power and Sample Size Estimation for Epigenome-Wide Association Scans to Detect Differential DNA Methylation. International Journal of Epidemiology, doi: 10.1093/ije/dyv041.

51. Mangino M, Cecelja M, Menni C, Tsai P-C, Yuan W, Small K, Bell J, Mtchell GF, AortaGen Consortium, Chowienczyk P, Spector TD. 2016. Integrated multiomics approach identifies calcium and integrin-binding protein-2 as a novel gene for pulse wave velocity. Journal of Hypertension, 34(1):79-87. doi: 10.1097/HJH.0000000000000732.

50. Martin TC, Yet I, Tsai P-C, and Bell JT. 2015. coMET: visualisation of regional epigenome-wide association scan results and DNA co-methylation patterns. BMC Bioinformatics, 16:131. doi:10.1186/s12859-015-0568-2.

49. Draisma HHM. Pool R, Kobl M, Jansen R, Petersen A-K, Vaarhorst A, Yet I, Haller T, Demirkan A, Esko T, Zhu G, Bohringer S, Beekman M, van Klinken JB, Prehn C, Adamski J, de Craen A, van Leeuwen E, Amin N, Dharuri H, Westra H-J, Franke L, de Geus E, Hottenga J-J, Willemsen G, Henders A, Montgomery G, Nyholt D, Whitfield J, Penninx B, Spector TD, Metspalu A, Slagboom E, van Dijk KW, Hoen PT, Strauch K, Martin N, van Ommen G-J, Illig T, Bell J, Mangino M, Suhre K, McCarthy M, Gieger C, Isaacs A, van Duijn C, and Boomsma D. 2015. Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels. Nature Communications, 6:7208. doi:10.1038/ncomms8208.

48. Taylor PN, Porcu E, Chew S, Campbell PJ, Traglia M, Brown SJ, Mullin BH, Shihab S, Min J, Walter K, Memari Y, Huang J, Barnes M, Beilby JP, Charoen P, Danecek P, Dudbridge F, Forgetta V, Celia Greenwood CMT, Grundberg E, Johnson AD, Hui J, Lim EM, McCarthy S, Muddyman D, Panicker V, Perry J, Bell JT, Yuan W, Relton C, Gaunt T, Schlessinger D, Abecasis G, Cucca F, Surdulescu GL, Woltersdorf W, Zeggini E, Zheng H-F, Toniolo D, Dayan CM, Naitza S, Walsh JP, Spector TD, Davey-Smith G, Durbin R, Richards JB, Soranzo N, Timpson NJ, Wilson SG and the UK10K Consortium. 2015. Whole genome sequence based analysis of thyroid function. Nature Communications, 6: 5681. doi:10.1038/ncomms6681.

47. Zhang W, Spector TD, Deloukas P, Bell JT*, Engelhardt BE*. 2015. Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements. Genome Biology, 16: 14.

2014

46. Yuan W*, Xia Y*, Bell CG, Yet I, Ferreira T, Ward K, Gao F, Loomis AK, Hyde CL, Wu H, Lu H, Liu Y, Small K, Vinuela A, Morris A, Berdasco M, Esteller M, Brosnan JM, Deloukas P, McCarthy MI, John SL, Bell JT*, Wang J*, Spector TD*. An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins. Nature Communications, 5: 5719. doi:10.1038/ncomms6719.

45. Tsaprouni LG, Yang T-P, Bell JT, Dick KJ, Kanoni S, Nisbet J, Vinuela A, Grundberg E, Nelson CP, Meduri E, Buil A, the MuTHER consortium, Cambien F, Hengstenberg C, Erdmann J, Schunkert H, Goodall AH, Ouwehand WH, Dermitzakis E, Spector TD, Samani N, and Deloukas P. Cigarette Smoking Reduces DNA Methylation Levels at Multiple Genomic Loci but the Effect is Partially Reversible upon Cessation. Epigenetics, 9:1382-96.

44. Goodrich JK, Waters JL, Poole AC, Sutter JL, Koren O, Blekhman R, Beaumont M, Van Treuren W, Knight R, Bell JT, Spector TD, Clark A, and Ley RE. 2014. Human Genetics Shape the Gut Microbiome. Cell, 159(4): 789-799. doi:10.1016/j.cell.2014.09.053. Highlighted in New Scientist F1000

43. Horvath S, Erhart W, Brosch M, Ammerpohl O, von Schnfels W, Ahrens M, Heits N, Bell JT, Tsai P-C, Spector TD, Deloukas P, Siebert R, Sipos B, Becker T, Rcken C, Schafmayer C, Hamped J. 2014. Obesity accelerates epigenetic aging of human liver. PNAS, 111(43):15538-43. doi: 10.1073/pnas.

42. Wolber L, Steves CJ, Tsai P-C, Deloukas P, Spector TD, Bell JT*, Williams FMK*. 2014. Epigenome-wide DNA methylation in hearing ability: new mechanisms for an old problem. PLoS One, 9(9):e105729. doi:10.1371/journal.pone.0105729.

41. Castillo-Fernandez JE, Spector, TD, and Bell JT. 2014. Epigenetics of discordant monozygotic twins: implications for disease. Genome Medicine. 6(7): 60. doi: 10.1186/s13073-014-0060-z.

40. Hoggart CJ, Venturini G, Mangino M, Gomez F, Ascari G, Zhao JH, Teumer A, Winkler TW, Tsernikova N, Luan J, Mihailov J, Ehret GB, Zhang W, Lamparter D, Esko T, Mace A, Reger S, Bochud P-Y, Barcella M, Dauvilliers Y, Benyamin B, Evans DM, Hayward C, Lopez MF, Franke L, Russo A, Heid IM, Salvi E, Vendantam S, Arking DE, Boerwinkle E, Chambers JC, Fiorito G, Grallert H, Guarrera S, Homuth G, Huffman JE, Porteous D, Generation Scotland Consortium, The LifeLines Cohort study, The GIANT Consortium, Moradpour D, Iranzo A, Hebebrand J, Kemp JP, Lammers GJ, Aubert V, Heim MH, Martin NG, Montgomery GW, Peraita-Adrados R, Santamaria J, Negro F, Schmidt CO, Scott RA, Spector TD, Strauch K, Volzke H, Wareham NJ, Yuan W, Bell JT, Chakravarti A, Kooner JS, Peters A, Matullo G, Wallaschofski H, Whitfield JB, Paccaud F, Vollenweider P, Bergmann S, Beckmann JS, Tafti M, Hastie ND, Cusi D, Bochud M, Frayling TM, Metspalu A, Jarvelin M-R, Scherag A, Davey Smith G, Borecki IB, Rousson V, Hirschhorn JN, Rivolta C, Loos RJF, Kutalik Z. 2014. Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent of origin effect on body mass index. PLoS Genetics, 10(7):e1004508. doi: 10.1371/journal.pgen.1004508.

39. Davies MN*, Lutz Krause L*, Bell JT*, Gao F, Ward KJ, Wu H, Lu H, Liu Y, Tsai PC, Collier DA, Mill J, UK Brain Expression Consortium, Henders A, Byrne E, Wray NR, Martin NG*, Spector TD* and Wang J*. 2014. Hypermethylation in the ZBTB20 gene is associated with Major Depressive Disorder: A Discordant Monozygotic Twin study. Genome Biology, 15:R56. doi: 10.1186/gb-2014-15-4-r56.

38. Bell JT, Loomis AK, Butcher LM, Gao F, Zhang B, Hyde CL, Sun J, Wu H, Ward K, Harris J, Scollen S, Davies MN, Schalkwyk LC, Mill J, The MuTHER Consortium, Williams FMK, Li N, Deloukas P, Beck S, McMahon SB, Wang J, John SL, and Spector TD. 2014. Differential methylation of TRPA1 promoter is associated with pain sensitivity. Nature Communications, 5:2978. doi:10.1038/ncomms3978. Highlighted in BBC New Scientist Forbes

2013

37. Menni C, Keser T, Mangino M, Bell JT, Erte I, Akmacic I, Vuckovic F, Pucic Bakovic M, Gornik O, McCarthy M, Zoldos V, Spector TD, Lauc G, Valdes AM. 2013. Glycosylation of Immunoglobulin G: Role of genetic and epigenetic influences. PLoS One, 8:e82558. doi: 10.1371/journal.pone.0082558.

36. Grundberg E, Meduri E, Sandling JK, Hedman AK, Keildson S, Nisbet J, Sekowska M, Wilk A, Barrett A, Small KS, Ge B, Carone M, Shin S-Y, Dermitzakis ET, McCarthy MI, Spector TD, Bell JT, Deloukas P. 2013. Global Analysis of DNA Methylation Variation in Adipose Tissue from Twins Reveals Links to Disease-Associated Variants in Distal Regulatory Elements. American Journal of Human Genetics, 93: 876-890. doi: 10.1016/j.ajhg.2013.10.004.

35. Menni C, Fauman E, Erte I, Perry J, Kastenmller G, Shin S-Y, Petersen A-K, Hyde C, Psatha M, Ward K, Yuan W, Milburn M, Palmer C, Frayling T, Trimmer J, Bell JT, Gieger C, Mohney R, Brosnan M, Suhre K, Soranzo N, Spector T. 2013. Biomarkers for type 2 diabetes and impaired fasting glucose using a non-targeted metabolomics approach. Diabetes, 62(12):4270-6. doi: 10.2337/db13-0570.

45. Di Rienzi SC, Sharon I, Wrighton KC, Koren O, Hug LA, Thomas BC, Goodrich JK, Bell JT, Spector TD, Banfield JF and Ley RE. 2013. The human gut and groundwater harbor non-photosynthetic bacteria belonging to a new candidate phylum sibling to Cyanobacteria. eLife, 2:e01102. doi: 10.7554/eLife.01102.

33. Menni C, Kastenmuller G, Petersen AK, Psatha M, Bell JT, Tsai P-C, Gieger C, Schulz H, Erte I, John S, Brosnan MJ, Wilson SG, Lim EM, Stuckey BGA, Mohney RP, Suhre K, Spector TD, and Valdes AM. 2013. Metabolomic markers reveal novel pathways of aging and early development in human populations. International Journal of Epidemiology, 42(4):1111-9, doi: 10.1093/ije/dyt094.

32. Drong AW, Nicholson G, Hedman AK, Meduri E, Grundberg E, Small KS, Shin S-Y, Bell JT, Karpe F, Soranzo N, Spector TD, McCarthy MI, Deloukas P, Rantalainen M, Lindgren C, for the MolPAGE Consortia. 2013. The presence of methylation quantitative trait loci indicates a direct genetic influence on the level of methylation in adipose tissue. PLoS One, 8(2):e55923.

2012

31. Tsai P-C, Spector TD, and Bell JT. 2012. Using Epigenome-Wide Association Scans of DNA Methylation for Age-Related Complex Human Traits. Epigenomics, 4: 511- 526.

30. Williams FM, Bansal AT, van Meurs JB, Bell JT, Meulenbelt I, Suri P, Rivadeneira F, Sambrook PN, Hofman A, Bierma-Zeinstra S, Menni C, Kloppenburg M, Slagboom PE, Hunter DJ, Macgregor AJ, Uitterlinden AG, Spector TD. 2012. Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects. Annals of Rheumatic Diseases, doi:10.1136/annrheumdis- 2012-201551.

29. Heyn H, Carmona FJ, Gomez A, Ferreira HJ, Bell JT, Sayols S, Ward K, Stefansson OA, Moran S, Sandoval J, Eyfjord JE, Spector TD, Esteller M. 2012. DNA methyla- tion profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker. Carcinogenesis, 34(1):102-8.

28. Bell JT and Spector TD. 2012. DNA methylation studies using twins: What are they telling us? Genome Biology, 13(10):172.

27. Grundberg E*, Small KS*, Hedman AK*, Nica AC*, Buil A*, Keildson S, Bell JT, Yang T-P, Barett A, Nisbet J, Wilk A, Shin S-Y, Glass D, Travers M, Min JL, Zondervan KT, Ring S, McArdle W, Thorleifsson G, Kong A, Thorsteindottir U, Ainali C, Dimas AS, Hassanali N, Ingle C, Knowles D, Krestyaninova M, Lowe CE, Meduri E, di Meglio P, Montgomery SB, Parts L, Potter S, Surdulescu G, Tsaprouni T, Tsoka S, Bataille V, Durbin R, Nestle FO, O’Rahilly S, Lindgren CM, Soranzo N, Ahmadi K, Schadt E, Stefansson K, Davey-Smith G, McCarthy MI*, Deloukas P*, Dermitzakis ET*, Spector TD*, for the MuTHER consortium. 2012. Mapping cis and trans regulatory effects across multiple tissues in twins: the MuTHER Study. Nature Genetics, 44(10):1084-1089.

26. Bell JT*, Tsai P-C*, Yang T-P, Pidsley R, Nisbet J, Glass D, Zhai G, Mangino M, Zhai G, Zhang F, Valdes A, Shin S-Y, Dempster EL, Murray RM, Grundberg E, Hedman AK, Nica A, Small KS, The MuTHER Consortium, Dermitzakis ET, McCarthy MI, Mill J, Spector TD*, Deloukas P*. 2012. Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population. PLoS Genetics, 8(4):e1002629. Highlighted in New Scientist The Independent Huffington Post

25. Bell JT and Saffery R. 2012. The value of twins in epigenetic epidemiology. International Journal of Epidemiology, 41(1): 140-150.

2011

24. Bell JT and Spector TD. 2011. A Twin approach to unraveling Epigenetics. Trends in Genetics, 27: 116-125.

23. Pai AA, Bell JT, Marioni JC, Pritchard JK, and Gilad Y. 2011. A Genome-wide Study of DNA Methylation Patterns and Gene Expression Levels in Multiple Human and Chimpanzee Tissues. PLoS Genetics, 7(2):e1001316. doi: 10.1371/journal.pgen.1001316. PMCID: PMC3044686.

22. Bell JT, Pai AA, Pickrell JK, Gaffney DJ, Pique-Regi R, Degner JF, Gilad Y, and Pritchard JK. 2011. DNA methylation patterns associate with genetic and gene-expression variation in HapMap cell lines. Genome Biology, 12(1):R10. doi: 10.1186/gb-2011- 12-1-r10. PMCID: PMC3091299.

21. Nica AC, Parts L, Glass D, Nisbet J, Barrett A, Sekowska M, Ingle C, Travers M, Potter S, Grundberg E, Small K, Hedman A, Bataille V, Tzenova Bell J, Surdulescu G, Dimas AS, Nestle FO, di Meglio P, Min JL, Wilk A, Hammond CJ, Hassanali N, Yang T-P, Montgomery SB, Lindgren CM, Zondervan KT, Soranzo N, Barroso I, Durbin R, Ahmadi K, Deloukas P, McCarthy MI, Dermitzakis ET, Spector TD, for the MuTHER Consortium. 2011. The architecture of regulatory gene variation across multiple human tissues: the MuTHER study. PLoS Genetics, 7(2):e1002003.

20. Bell JT, Timpson NJ, Rayner NW, Zeggini E, Frayling TM, Hattersley AT, Morris AP, Mc- Carthy MI. 2011. Genome-wide association scan allowing for epistasis in type 2 dia- betes. Annals of Human Genetics, 75(1):10-9. doi: 10.1111/j.1469-1809.2010.00629.x PMCID: PMC3430851.

19. Zhai G*, Teumer A*, Stolk L*, Perry J*, Vandenput L*, Coviello D*, Koster A*, Bell JT, Bhasin S, Eriksson J, Eriksson A, Ernst F, Ferrucci L, Frayling TM, Glass D, Grundberg E, Haring R, Hedman AK, Hofman A, Kiel DP, Kroemer HK, Liu Y, Lunetta KL, Lorentzon M, Mangino M, Melzer D, Miljkovic I, MuTHER consortium, Nica A, Penninx B, Ramachandran V, Small KS, Soranzo N, Uitterlinden AG, Vlzke H, Wilson S, Zhuang WV, Harris T*, Murabito JM*, Ohlsson C*, Murray A*, de Jong F*, Spector TD*, and Wallaschofski H*. 2011. Eight Common Genetic Variants Associated with Serum DHEAS Levels Suggest a Key Role in Ageing Mechanisms. PLoS Genetics, 7(4):e1002025.

pre-2011

18. Cox A, Ackert-Bicknell C, Dumont BL, Ding Y, Bell JT, Brockmann GA, Wergedal JE, Bult C, Paigen B, Flint J, Tsaih S-W, Churchill G, and Broman KW. 2009. A New Standard Genetic Map for the Laboratory Mouse. Genetics, 182(4):1335-44. doi: 10.1534/genetics.109.105486. PMCID: PMC2728870.

17. Ramagopalan SV, Herrera BM, Bell JT, Dyment DA, DeLuca GC, Lincoln MR, Orton SM, Chao MJ, Sadovnick AD, and Ebers GC. 2008. Parental Transmission of HLA- DRB1*15 in Multiple Sclerosis. Human Genetics, 122(6):661-3. doi: 10.1007/s00439- 007-0442-z.

16. Schneider JE, Stork L-A, Bell JT, ten Hove M, Isbrandt D, Clarke K, Watkins H, Lygate CA, and Neubauer S. 2008. Cardiac structure and function during ageing in energet- ically compromised Guanidinoacetate N-methyltransferase (GAMT)-knockout mice - a one year longitudinal MRI study. Journal of Cardiovascular Magnetic Resonance, 10(1):9. doi: 10.1186/1532-429X-10-9. PMCID: PMC2254407.

15. Bartlett CW, Vieland VJ, Bartlett J, Bell JT, Bhattacharjee S, Clerget-Darpoux F, Bush WS, Edwards TL, Gao G, Halder I, Huang Y, Kotti S, Larkin EK, Li H, Motsinger AA, Mukhopadhyay N, Namkung J, Park T, Ritchie MD, Stein CM, Zhou JY. 2007. Discussing gene-gene interaction: warning–translating equations to English may re- sult in jabberwocky. Genet Epidemiol, 31 Suppl 1:S61-7. doi: 10.1002/gepi.20281.

14. Bell JT. 2007. A two-dimensional genome scan for rheumatoid arthritis susceptibility loci. BMC Proceedings, 1(Suppl 1):S63. PMCID: PMC2367545.

13. Herrera BM, Cader ZM, Dyment DA, Bell JT, DeLuca GC, Willer CJ, Lincoln MR, Ramagopalan SV, Orton SM, Chao MJ, Sadovnick AD, and Ebers GC. 2007. Multiple sclerosis susceptibility and the X chromosome. Multiple Sclerosis, 13(7):856-864. doi: 10.1177/1352458507076961.

12. Shifman S, Bell JT, Copley RR, Taylor M, Mott R, Flint J, and Williams RW. 2007. Evidence of a Large-Scale Functional Organization of Mammalian Chromosomes: Authors’ Reply. PLoS Biology 5(5):e128. PMCID: PMC1868062.

11. Shifman S, Bell JT, Copley RR, Taylor M, Williams RW, Mott R, and Flint, J. 2006. A high resolution SNP genetic map of the mouse genome. PLoS Biology, 4(12):e395. doi :10.1371/journal.pbio.0040395. PMCID: PMC1635748.

10. Wiltshire S*, Bell JT*, Groves CJ, Dina C, Hattersley AT, Frayling TM, Walker M, Hitman GA, Vaxillaire M, Farrall M, Froguel P and McCarthy MI. 2006. Epis- tasis Between Type 2 Diabetes Susceptibility Loci on Chromosomes 1q21-25 and 10q23-26 in Northern Europeans. Annals of Human Genetics 70: 726-737. doi: 10.1111/j.1469-1809.2006.00289.x.

9. Tosh K, Ravikumar M, Bell JT, Meisner S, Hill AVS, and Pitchappan R. 2006. Variation in MICA and MICB genes and enhanced susceptibility to leprosy in South India. Human Molecular Genetics 15(19): 2880-2887. doi: 10.1093/hmg/ddl229.

8. Herrera BM, Cader ZM, Dyment DA, Bell JT, Ramagopalan SV, Lincoln MR, Orton SM, Chao MJ, Sadovnick AD, and Ebers GC. 2006. Follow-up investigation of twelve proposed linkage regions in multiple sclerosis. Genes and Immunity 7(5): 366-371. doi: 10.1038/sj.gene.6364308.

7. Bell JT, Wallace C, Dobson R, Wiltshire S, Mein C, Pembroke J, Brown M, Clayton D, Samani N, Dominiczak A, Webster J, Lathrop M, Connell J, Munroe P, Caulfield M, and Farrall M. 2006. Two-dimensional genome-scan reveals novel epistatic loci for essential hypertension. Human Molecular Genetics 15(8):1365-1374. doi: 10.1093/hmg/ddl058.

6. Lamb J, Barnby G, Bonora E, Sykes N, Bacchelli E, Blasi F, Maestrini E, Broxholme J, Tzenova J (Bell JT), Weeks D, Bailey A, Monaco A, and the International Molecular Genetic Study of Autism Consortium (IMGSAC). 2005. Analysis of IMGSAC autism susceptibility loci: evidence for sex-limited and parent-of-origin specific effects. The Journal of Medical Genetics 42:132-137. doi: 10.1136/jmg.2004.025668.

5. PROCARDIS Consortium. 2004. A trio family study showing association of the lymphotoxin-alpha N26 (804A) allele with coronary artery disease. European Jour- nal of Human Genetics, 12(9):770-4. See www.procardis.org for author list. doi: 10.1038/sj.ejhg.5201244.

4. Tzenova J (Bell JT), Kaplan BJ, Petryshen TL, and Field LL. 2004. Confirmation of a dyslexia susceptibility gene on chromosome 1p in a set of 100 Canadian families. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 127B:117-124. doi: 10.1002/ajmg.b.20139.

3. Petryshen TL, Kaplan BJ, Hughes ML, Tzenova J (Bell JT), and Field LL. 2003. Supportive evidence for the DYX3 dyslexia susceptibility gene in Canadian families. The Journal of Medical Genetics, 39(2):125-6. PMCID: PMC1735047.

2. Jones AO, Tzenova J (Bell JT), Fujiwara TM, Frappier D, Crumley MJ, Roslin N, Kos CH, Tieder M, Langman CB, Proesmans W, Carpenter TO, Rice A, Anderson D, Morgan K and Tenenhouse HS. 2001. Hereditary Hypophosphatemic Rickets with Hypercalciuria is Not Caused By Mutations in the Na/Pi Cotransporter NPT2 (SLC34A1) Gene. Journal of the American Society of Nephrology 12: 507-512.

1. Turecki G, Zhu J, Tzenova J (Bell JT), Lesage A, Seguin M, Tousignant M, Chawky N, Vanier C, Lipp O, Alda M, Joober R, Benkelfat C, and Rouleau G. 2001. TPH and Suicidal behavior of a study of suicide completers. Molecular Psychiatry, 6: 98-102. PMID: 11244493.