Publications
"Syntheses of the ω-pyridinium-containing very-long-chain ceramides PyrCer(24:1(15Z)) and PyrCer(24:0) and their anticancer activity "
Ju Young Ko, Mi-Yeon Kim, Ji-Yoon Jeon, Jin Yi Jung, Yong-Hyun Han,* Jae Hyun Kim*
Bioorg. Med. Chem. Lett. 2024, 98, 129585. Link
"Alicyclic-Amine-Derived Imine-BF3 Complexes: Easy-to-Make Building Blocks for the Synthesis of Valuable α-Functionalized Azacycles"
Subhradeep Dutta,† Jae Hyun Kim,† Kamal Bhatt, Dillon R. L. Rickertsen, Khalil A. Abboud, Ion Ghiviriga, Daniel Seidel*
Angew. Chem. Int. Ed. 2024, 63, e202313247. Link
"Recent asymmetric synthesis of natural products bearing an α-tertiary amine moiety via temporary chirality induction strategies"
Hongjun Jeon,† Jae Hyun Kim,† Sanghee Kim*
Nat. Prod. Rep. 2024, 41, 228-250. Link
"Blockade of sphingosine-1-phosphate receptor 4 pathway has anti-inflammatory effects in a murine model of allergic airway inflammation"
Mini Jeong, Sin-Jeong Kim, Kyomoon Koo, A Ryang Lee, Min Ju Pyo, Hyun Jae Shim, Keun-Ai Moon, Ji-Hyang Lee, Chung Hwan Hong, Jae Hyun Kim, Hyunkyung Cho, Eun Hee Koh, Ki-Up Lee, Sanghee Kim, Sun-Young Yoon,* You-Sook Cho*
Allergy 2023, 78, 2033-2036. Link
"Short and scalable synthesis of cynandione A"
Seoungwoo Kang, Yeonjoon Kim, Seonah Kim, Ju Young Ko, Jae Hyun Kim*
Org. Biomol. Chem. 2023, 21, 1868-1871. Link
"Evolution of a Strategy for Concise Enantioselective Total Synthesis of the Salinosporamide Family of Natural Products"
Soojun Park, Jiwoo Lee, Jae Hyun Kim, Yeji Jeong, Seokwoo Lee, Su Won Lee, Sanghee Kim*
Angew. Chem. Int. Ed. 2022, e202210317 / Hot paper Link
"Adipocyte lysoplasmalogenase TMEM86A regulates plasmalogen homeostasis and protein kinase A-dependent energy metabolism"
Yoon Keun Cho,† Young Cheol Yoon,† Hyeonyeong Im,† Yeonho Son, Minsu Kim, Abhirup Saha, Cheoljun Choi, Jaewon Lee, Sumin Lee, Jae Hyun Kim, Yun Pyo Kang, Young-Suk Jung, Hong Koo Ha, Je Kyung Seong,* James G. Granneman,* Sung Won Kwon,* Yun-Hee Lee* (†equally contributed)
Nat. Commun. 2022, 13, 4084. Link
Chung Hwan Hong,† Myoung Seok Ko,† Jae Hyun Kim,† Hyunkyung Cho, Chi-Ho Lee, Ji Eun Yoon, Ji-Young Yun, In-Jeoung Baek, Jung Eun Jang, Seung Eun Lee, Yun Kyung Cho, Ji Yeon Baek, Soo Jin Oh, Bong Yong Lee, Joon Seo Lim, Jongkook Lee, Sean M. Hartig, Laura Conde de la Rosa, Carmen Garcia-Ruiz, Ki-Up Lee, Jose C. Fernández-Checa,* Ji Woong Choi,* Sanghee Kim,* Eun Hee Koh* (†equally contributed)
Cell. Mol. Gastroenterol. Hepatol. 2022, 13, 3, 925-947. Link
"Memory of Chirality in the Asymmetric Synthesis of Piperidines with Vicinal Stereocenters by Intramolecular SN2′ Reaction"
Seungbae Park,† Seokwoo Lee,† Jae Hyun Kim, Won Jun Choi, Sanghee Kim* (†equally contributed)
Chem. Asian J. 2021, 16, 3097-3101. Link
"Asymmetric Total Synthesis of Oxazolomycins B and C"
Yeonghun Song, Jae Hyun Kim, Young Chan Kim, Sanghee Kim*
Chem. Eur. J. 2021, 27, 10731-10736. Link
"Collective Asymmetric Total Synthesis of C‐11 Oxygenated Cephalotaxus Alkaloids"
Jae Hyun Kim,† Hongjun Jeon,† Choyi Park, Soojun Park, and Sanghee Kim* (†equally contributed)
Angew. Chem. Int. Ed. 2021, 60, 12060-12065. Link
"α-C–H Bond Functionalization of Unprotected Alicyclic Amines: Lewis-Acid-Promoted Addition of Enolates to Transient Imines"
Jae Hyun Kim,† Anirudra Paul,† Ion Ghivirga, and Daniel Seidel* (†equally contributed)
Org. Lett. 2021, 23, 797-801. Link
"Diversification of unprotected alicyclic amines via C–H bond functionalization: Decarboxylative alkylation of transient imines"
Anirudra Paul,† Jae Hyun Kim,† Scott D. Daniel, and Daniel Seidel* (†equally contributed)
Angew. Chem. Int. Ed. 2021, 60, 1625-1628. Link
"Catalyst‐ and Base‐Free Asymmetric Synthesis of Functionalized Prolines via One‐Pot Cascade Reactions"
Hyunkyung Cho, Jinju Kim, Jae Hyun Kim, Yeonghun Song, and Sanghee Kim*
Adv. Synth. Catal. 2020, 362, 2941-2946. Link
"Stereoselective Asymmetric Synthesis of Pyrrolidines with Vicinal Stereocenters Using a Memory of Chirality-Assisted Intramolecular SN2′ Reaction"
Jae Hyun Kim, Yundong Chung, Hongjun Jeon, Seokwoo Lee, and Sanghee Kim*
Org. Lett. 2020, 22, 3989–3992. Link
"Asymmetric Total Synthesis of Inthomycins A, B, and C"
Jae Hyun Kim,† Yeonghun Song,† Min Jung Kim and Sanghee Kim* (†equally contributed)
J. Org. Chem. 2020, 85, 4795-4806. Link
"Asymmetric Total Synthesis of (+)-Neooxazolomycin Using a Chirality Transfer Strategy"
Jae Hyun Kim, Illan Kim, Yeonghun Song, Min Jung Kim, and Sanghee Kim*
Angew. Chem. Int. Ed. 2019, 58, 11018–11022. Link
"Amide Acetal in Palladium-Catalyzed Allylation with Allylic Alcohols under Neutral Conditions"
Yongseok Kwon,† Jaehyun Jung,† Jae Hyun Kim, Woo-Jung Kim, Sanghee Kim* (†equally contributed)
Asian J. Org. Chem. 2017, 6, 520–526. Link
"Asymmetric Total Synthesis of Lepadiformine C Using Memory of Chirality in an Intramolecular Ester Enolate Michael Addition"
Seokwoo Lee, Minsik Bae, Jinkyung In, Jae Hyun Kim, and Sanghee Kim*
Org. Lett. 2017, 19, 254–257. Link
"Biomimetic Total Synthesis of (-)-Penibruguieramine A Using Memory of Chirality and Dynamic Kinetic Resolution"
Jae Hyun Kim, Seokwoo Lee, and Sanghee Kim*
Angew. Chem. Int. Ed. 2015, 54, 10875–10878. Link
"Phase Transfer Agent Assisted Biphasic CuAAC Reaction"
Jae Hyun Kim, and Sanghee Kim*
RSC Adv. 2014, 4, 26516-26523. Link
"Design and Evaluation of ω-Hydroxy Fatty Acids Containing α-GalCer Analogues for CD1d-Mediated NKT Cell Activation"
Chaemin Lim, Jae Hyun Kim, Dong Jae Baek, Joo-Youn Lee, Minjae Cho, Yoon-Sook Lee, Chang-Yuil Kang, Doo Hyun Chung, Won-Jae Cho, and Sanghee Kim*
ACS Med. Chem. Lett. 2014, 5, 331-335. Link
"Total Synthesis of the Proposed Structure of Trocheliophorolide D"
Soonho Hwang, Jae Hyun Kim, Hak Sung Kim, and Sanghee Kim*
Eur. J. Org. Chem. 2011, 7414-7418. Link
"The 3-Deoxy Analogue of a-GalCer: Disclosing the Role of the 4-Hydroxyl Group for CD1d-Mediated NKT Cell Activation"
Dong Jae Baek, Jeong-Hwan Seo, Chaemin Lim, Jae Hyun Kim, Doo Hyun Chung, Won-Jea Cho, Chang-Yuil Kang, and Sanghee Kim*
ACS Med. Chem. Lett. 2011, 2, 544-548. Link