Research
Research
My projects focus on ecosystem dynamics across the tree of life. My work centers on the integration of biological and physical datasets to better understand, responsibly manage and functionally restore the environment.
Postdoctoral work: Splicing and transcription
Ares Lab, University of California Santa Cruz
Engineered transcriptional pauses and splicing!
(PDB:7B0Y here for your enjoyment)
Nascent RNA captured and sequenced by inosine-tailing!
(DALL-e art prompt "RNA Break my Soul" here for you)
Thesis work: How heme plays a key role in miRNA biogenesis
Guo lab, University of California Los Angeles
A metal molecule , harvested from the planet via our diet, drives the way our body regulates its gene expression. The microRNA biogenesis mechanism requires the biometal Fe3+ bound by the porphyrin heme!
You can read about how the RNA binding heme domain was discovered, and how mutations in this domains were used to detect the availble pool of iron in human cells by clicking right here!