March 2, 2025
Applying the Health Equity Framework to Indigenous Renal Inequities in British Columbia
When evaluating renal services for Indigenous peoples in British Columbia, the Health Equity Framework (HEF) provides a foundation for developing strategies to address disparities. In Canada, "Indigenous peoples" includes First Nations, Métis, and Inuit, with over 600 distinct communities (Chaturvedi et al., 2024). While health equity is a priority in British Columbia, the social determinants approach often lacks public support and fails to tackle systemic inequities. (Government of British Columbia [BC Gov], 2025; Peterson, Charles, Yeung, & Coyle, 2021). Therefore, a multilevel model will be used called the HEF. The framework centres on Health and Education Outcomes, influenced by four intersecting spheres: Physiological Pathways, Individual Factors, Relationships and Networks, and Systems of Power (Peterson et al., 2021). Examining these spheres in relation to Indigenous populations highlights critical pathways to improving kidney care in British Columbia.
Health Equity Framework
Health Equity Framework. Taken from The health equity framework: A science- and justice-based model for public health researchers and practitioners, by A. Peterson, V. Charles, D. Yeung, & K. Coyle, 2021, Health Promotion Practice, 22(6), 741-746. https://doi.org/10.1177/1524839920950730. Copyright 2021 by SAGE Publications. Reprinted with permission.
Physiological Pathways
Physiological pathways encompass biological, physical, cognitive, and psychological abilities that affect health outcomes (Peterson et al., 2021). There are many examples of physiological pathways to chronic kidney disease in Indigenous communities.
For example, chronic stress, historical trauma, and environmental factors contribute to higher rates of kidney disease (Park, 2021; Xu, Nie, Ding, & Hou, 2018). Early life adversities, such as food insecurity, unsafe drinking water, and exposure to pollutants, can disrupt neuroendocrine and immune system functions, increasing the risk of chronic conditions like diabetes and hypertension (Berens, Jensen, & Nelson, 2017; Vaiserman & Koliada, 2017). Further, diabetes, hypertension, and Indigenous identity are well-established risk factors for chronic kidney disease (CKD) (KDIGO, 2024). Additionally, genetic analyses have identified elevated inflammatory markers such as C-reactive protein and fibrinogen among healthy Indigenous individuals, with even higher levels observed in those with CKD compared to their non-Indigenous counterparts (Ferguson et al., 2024). These insights emphasize the need for culturally safe and trauma-informed care for Indigenous populations, considering the impact of historical trauma and environmental stressors (Chaturvedi et al., 2024). Further, action is needed to improve living conditions by ensuring access to food, clean water, and reducing pollution (Berens, Jensen, & Nelson, 2017; Vaiserman & Koliada, 2017).
Additionally, comprehensive screening for diabetes, hypertension, and CKD is essential for early detection and management in at-risk communities (CanSolve, n.d.). Screening serves as an ideal entry point to renal services because it can prevent the progression of CKD. Early detection through screening allows for timely interventions, reducing the need for more intensive treatments and improving patient outcomes. (KDIGO, 2024). Reviewing the physiological pathways of the HEF highlights key exposures that increase the risk of kidney disease in Indigenous populations and highlights the importance of targeted strategies to address these risks.
Individual Factors
Health behaviours and attitudes significantly influence access to kidney resources and affect health outcomes (BC Gov, 2020; Peterson et al., 2021). Historical and ongoing experiences of culturally unsafe care have led to deep-seated mistrust in the healthcare system among Indigenous communities (BC Gov, 2020). This mistrust contributes to lower screening rates and delayed diagnosis, exacerbating disease progression (Bello et al., 2019; CanSolve, n.d.; Lavoie et al., 2023).
To improve engagement, healthcare models must align with Indigenous perspectives on health. Community-based care initiatives, where Indigenous healthcare workers deliver services, can foster trust and encourage participation in screening and treatment programs (Harasemiw, Komenda, & Tangri, 2022). Strengthening Indigenous-led healthcare services can ensure that care delivery aligns with community values, increasing patient trust and participation (Harasemiw, Komenda, & Tangri, 2022). Supporting Indigenous care providers through funding and resource allocation will enhance the effectiveness of these model (Harasemiw, Komenda, & Tangri, 2022). Additionally, integrating holistic, culturally safe kidney care models, which emphasize community well-being and traditional healing practices, can improve long-term health outcomes (Chaturvedi et al., 2024). Creating safe environments within healthcare facilities by incorporating Indigenous artwork, language, and staff trained in culturally competent care will further enhance patient engagement and trust (Harasemiw, Komenda, & Tangri, 2022).
An example of a this is Kidney Check. Kidney Check is a program that addressed these physiological pathways and individual factors. Kidney Check, a Can-SOLVE initiative, is a patient centred, culturally safe program for Indigenous communities in five provinces, including British Columbia (CanSolve, n.d.). It uses screening questions and point-of-care tools to identify kidney disease risk. Developed with Indigenous partners, the program is effective (CanSolve, n.d.). Despite this, the Kidney Check and Interior Health Kidney Care Clinics are not well connected highlighting the need for stronger partnership. Strengthening this connection will enhance continuity of care and improve kidney health outcomes for Indigenous communities.
Watch the following video about how KidneyCheck created a program to screen for kidney disease with the Indigenous communities at the heart of it. Karmen Omeasoo shares about being diagnosed with kidney disease (KidneyCheck, 2021).
Relationships and Networks
Relationships and networks include the many connections between people and support structure environments (Peterson et al., 2021). Strong networks are essential for improving Indigenous health outcomes. Many Indigenous patients face barriers to care, including geographical isolation, lack of transportation, and the emotional toll of being separated from their support systems when accessing treatment (Harasemiw, Komenda, & Tangri, 2022).
Further, expanding home-based dialysis options can help patients remain in their communities, reducing disruptions to their social and cultural networks (Harasemiw, Komenda, & Tangri, 2022). This is particularly critical for Elders, whose presence and guidance are integral to community well-being (Harasemiw, Komenda, & Tangri, 2022). With this understanding, BC Renal supports a home-first approach through its publicly available It’s Better at Home video series and healthcare-focused guidelines (BC Renal, n.d., It’s better at home). Within Interior Health, my team actively utilizes these resources and promotes home dialysis modalities, recognizing their role in improving patients' quality of life.
Watch this video describing what the It's Better at Home policy is all about. Shannon Humchitt shares a personal account about having to relocate after a kidney diagnosis and the difference a home modality option made (BC Renal, n.d., It’s better at home).
Systems of Power
Systems of power refer to policies, processes, and practices that determine the distribution and access to resources required to be healthy (Peterson et al., 2021). These systems, when shaped by structural bias, can create barriers to equitable care (BC Gov, 2020; Peterson et al., 2021). A critical component of addressing systemic inequities in kidney care involves improving screening processes and fostering culturally safe healthcare organizations.
Screening is essential in kidney care to prevent CKD progression and avoid invasive treatments (KDIGO, 2024). While access to all renal services is important, pre-dialysis interventions are more impactful as they affect a broader population (KDIGO, 2024). Currently, British Columbia renal programs rely heavily on referrals from primary care providers which require multiple steps: Ordering diagnostics, reviewing results, entering referrals to the Kidney Care Clinic (KCC), and prescribing the appropriate CKD treatments (BC Renal, n.d., Best practices). A more effective system for Indigenous communities would involve active surveillance, automatic referrals for follow-up diagnostics, and stronger support for Indigenous-led healthcare services in rural areas (Harasemiw, Komenda, & Tangri, 2022). This system should monitor CKD diagnostics with automatic referrals to the KCC for those meeting criteria, reducing primary care workload (Harasemiw, Komenda, & Tangri, 2022; KDIGO, 2024). As part of their basic function, KCC would ensure correct treatments are prescribed (BC Renal, n.d., Best practices).
Additionally, since diabetes is a primary cause of CKD, surveillance for positive diabetes diagnostic results with automatic referrals for CKD diagnostics would improve early detection (Harasemiw, Komenda, & Tangri, 2022; KDIGO, 2024). This process would reduce barriers, bypass bias, and ensure access to clinical expertise. Further, despite concerns about rural resources, Indigenous healthcare services often outperform primary care in kidney disease surveillance, highlighting their effectiveness (Bello et al., 2019). This is particularly notable given that primary care often receives more funding (Bello et al., 2019). Strengthening these Indigenous services will improve early detection and treatment, addressing kidney health needs and bridging gaps in care.
Beyond screening, in order for any strategy to be effective, it has to be embedded in a culturally safe organization. A culturally safe organization prioritizes the representation of Indigenous health workers and ensures Indigenous partners are actively involved in decision-making processes (BC Gov, 2020). This fosters an environment where cultural perspectives are respected and valued. Additionally, cultural humility in education is essential, where healthcare professionals engage in continuous learning about Indigenous cultures, histories, and health needs, recognizing the importance of self-reflection and open-mindedness in providing effective and respectful care (Harasemiw, Komenda, & Tangri, 2022). Implementing these strategies lays the foundation for creating exceptional kidney care within a culturally safe organization.
This is a powerful overview and expansion on what we have discussed including lived experiences of systemic racism and what the First Nations Health Authority in BC recommends to improve cultural safety and humility (First Nations Health Authority, 2024)
Conclusion
The HEF offers a structured approach to addressing disparities in kidney care for Indigenous peoples in British Columbia. By examining physiological pathways, individual factors, relationships and networks, and systems of power, the framework identifies critical barriers to equitable healthcare access. Key strategies include culturally safe, trauma-informed care, early screening, Indigenous-led healthcare initiatives, and systemic reforms to improve resource distribution. Strengthening Indigenous healthcare services and fostering community-driven solutions can enhance kidney health outcomes and build trust in the healthcare system.
BC Renal. (n.d.). Best practices: Kidney care clinics. BC Renal. http://www.bcrenal.ca/resourcegallery/Documents/Best_Practices-Kidney_Care_Clinics.pdf
BC Renal. (n.d.). It’s better at home [Video]. YouTube. https://www.youtube.com/watchv=_hqSQUEq_cQ&list=PLgaBYChIaS-3KSuGH67qNWYhiJ9ygJHFJ&index=2
Bello AK, Ronksley PE, Tangri N, et al. (2019). Quality of Chronic Kidney Disease Management in Canadian Primary Care. JAMA Network Open, 2(9), e1910704. https://doi.org/10.1001/jamanetworkopen.2019.10704
Berens, A.E., Jensen, S.K.G. & Nelson, C.A. (2017). Biological embedding of childhood adversity: from physiological mechanisms to clinical implications. BMC Med, 15, 135. https://doi.org/10.1186/s12916-017-0895-4
CanSolve. (n.d.). Kidney Check. CanSolve. https://cansolveckd.ca/research-projects/kidney-check/
Chaturvedi, S., Bianchi, M. E. V., Bello, A., Crowshoe, H., & Hughes, J. T. (2024). Barriers to optimal kidney health among Indigenous peoples. Kidney International Reports, 9(3), 508–511. https://doi.org/10.1016/j.ekir.2024.01.038
Ferguson, B., Doan, V., Shoker, A. et al. (2024). A comprehensive exploration of chronic kidney disease and dialysis in Canada’s Indigenous population: From epidemiology to genetic influences. International Urology and Nephrology, 56, 3545–3558. https://doi.org/10.1007/s11255-024-04122-5
First Nations Health Authority. (2024). BC Cultural Safety and Humility Standard Documentary [Video]. YouTube. https://www.youtube.com/watch?v=76eJ3_MmgYs
Government of British Columbia. (2025). Closing the gap: A primer to reduce population health inequities in British Columbia. Government of British Columbia. https://www2.gov.bc.ca/assets/gov/health/about-bc-s-health-care-system/publichealth/pph-framework/bc_population_and_public_health_closing_the_gap_primer_jan_2025.pdf
Government of British Columbia. (2020). In plain sight: Addressing Indigenous-specific racism and discrimination in B.C. health care. Government of British Columbia. https://engage.gov.bc.ca/app/uploads/sites/613/2020/11/In-Plain-Sight-Summary-Report.pdf
Harasemiw, O., Komenda, P., & Tangri, N. (2022). Addressing inequities in kidney care for Indigenous people in Canada. Journal of the American Society of Nephrology, 33(8), 1474–1476. https://doi.org/10.1681/ASN.2022020215
KDIGO. (2024). KDIGO 2024 chronic kidney disease guideline. Kidney Disease Improving Global Outcomes. https://kdigo.org/wp-content/uploads/2024/03/KDIGO-2024-CKD-Guideline.pdf
Kidney Check. (2021). Kidney Check: Identifying kidney disease and diabetes in Indigenous communities [Video]. YouTube. https://www.youtube.com/watch?v=i4EgWXA8Sxs&t=4s
Lavoie, J. G., McLeod, L., Zacharias, J., et al. (2023). How systemic racism results in poorer outcomes for First Nations, and what First Nations are doing about it: The example of kidney health. Research Square. https://doi.org/10.21203/rs.3.rs-3694294/v1
Park, J. (2021). Mortality among First Nations people, 2006 to 2016. Statistics Canada. https://www150.statcan.gc.ca/n1/en/pub/82-003-x/2021010/article/00001-eng.pdf?st=B1NrDRsA
Peterson, A., Charles, V., Yeung, D., & Coyle, K. (2021). The health equity framework: A science- and justice-based model for public health researchers and practitioners. Health Promotion Practice, 22(6), 741-746. https://doi.org/10.1177/1524839920950730
Vaiserman, A.M., Koliada, A.K. (2017). Early-life adversity and long-term neurobehavioral outcomes: epigenome as a bridge?. Human Genomics. https://doi.org/10.1186/s40246-feefebb017-0129-z
Xu, X., Nie, S., Ding, H., & Hou, F. F. (2018). Environmental pollution and kidney diseases. Nature Reviews Nephrology, 14(5), 313-324. https://doi.org/10.1038/nrneph.2018.11