Akanmori, N.N., Junop, M.S., Gupta, R.S., & Park, J. Conformational flexibility of human ribokinase captured in seven crystal structures. International Journal of Biological Macromolecules. 2025 April; 299:140109
Ezekiel, S.J., Searle, M., & Park, J. Engineering dimer mutants of human geranylgeranyl pyrophosphate synthase. PLoS One. 2025 January 15; 20(1):e0317437.
Salari, S., Lee, H.-F., Tsantrizos, Y.S., & Park, J. Inhibition of human mevalonate kinase by allosteric inhibitors of farnesyl pyrophosphate synthase. FEBS Open Bio. 2024 June 23; 14(8): 1320–1339.
Lee, H.-F., Lacbay, C.M., Boutin, R., Matralis, A.N., Park, J., Waller, D.D., Guan, T.L., Sebag, M., & Tsantrizos, Y.S. Synthesis and evaluation of structurally diverse C-2-substituted thienopyrimidine-based inhibitors of the human geranylgernayl pyrophosphate synthase. J Med Chem. 2022 Jan 25; 65(3):2417–2496.
Bassenden, A.V., Dumalo, L., Park, J., Blanchet, J., Maiti, K., Arya, D.P., & Berghuis, A.M. Structural and phylogenetic analyses of resistance to next-generation aminoglycosides conferred by AAC(2') enzymes. Sci Rep. 2021 Jun 2; 11:11614.
Zielinski, M., Park, J., Sleno, B., & Berghuis, A.M. Structural and functional insights into esterase-mediated macrolide resistance. Nat Commun. 2021 Mar 19; 12:1732.
Park, J., Pandya, V.R., Ezekiel, S.J., & Berghuis, A.M. Phosphonate and bisphosphonate inhibitors of farnesyl pyrophosphate synthases: a structure-guided perspective. Front Chem. 2021 Jan 6; 8:612728.
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