Principal investigator
Senior Researcher
Dementia Research Group
Korea Brain Research Institute
Email: kim_jaekwang@kbri.re.kr
Office: +82-53-980-8390
Lab: +82-53-980-8171
Fax: +82-53-980-8399
1996 - 2001 B.S., Department of Microbiology, Seoul National University, Seoul, Korea
2001 - 2007 Ph.D., School of Biological Sciences, Seoul National University, Seoul, Korea
2007 – 2008 Postdoc, The Institute of Microbiology, Seoul National University, Seoul, Korea
2008 – 2009 Postdoc, Department of Pathology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA
2009 – 2010 Postdoc, Department of Neuroscience, Medical School, University of Minnesota, Minneapolis, MN, USA
2010 – 2013 Postdoc/staff scientist, Department of Neurology, School of Medicine, Washington University, St. Louis, MO, USA
2013 – 2017 Senior Research Fellow/ Research Associate, Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, FL, USA
2017 Assistant Professor, Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, FL, USA
2017 – present Senior Researcher, Dementia Research Group, Korea Brain Research Insititutue, Daegu, Korea
1. Choi J*, Gao J*, Kim J*, Hong C, Kim J, Tontonoz P (2015), The E3 ubiquit in ligase Idol controls brain LDL receptor levels, ApoE clearance and Aβ amyloidosis, Sci Transl Med. 7(314): 314ra184.* equally contributed.
2. Kim J*, Fiesel FC, Belmonte KC, Hudec R, Wang WX, Kim C, Nelson PT, Springer W, Kim J* (2016) miR-27a and miR-27b regulate autophagic clearance of damaged mitochondria by targeting PTEN-induced putative kinase 1 (PINK1), Mol Neurodegener. 11(1):55. *co-corresponding authors.
3. Bok E, Leem E, Lee B-R, Lee JM, Yoo CJ, Lee EM, Kim J (2021) Role of the Lipid membrane and membrane proteins in tau pathology, Front Cell Dev Biol., 9: 653815
4. Bhurtel S, Bok E, Katila N, Kim J*, Choi D-Y* (2021), Activation of Nrf2 by methylene blue is associated with the neuroprotection against MPP + induced toxicity via ameliorating oxidative stress and mitochondrial dysfunction, Biochem Pharmacol, 192:114719, *co-corresponding authors.
5. Chang Jae Yoo, Youngtae Choi, Eugene Bok, Yuxi Lin, Mookyung Cheon, Young-Ho Lee, Jaekwang Kim* (2024) Complement receptor 4 mediates the clearance of extracellular tau fibrils by microglia. FEBS J. 291(15):3499-3520.
6. Nam Y*, Kim S*, Lee J-Y*, Kim J*, Kim SR (2025) Enhancing the anti-aging potential of the nigrostriatal dopamine system to counteract age-related motor decline. Signal Transduct Target Ther. 10(1):153. * equally contributed.