Evolution of genes and species at a large-scale:

a practical approach to novel phylogenetic methods in the postgenomic era

The field of phylogenetics is growing faster than ever: large-scale genome projects are generating an unprecedented amount of data and there is a parallel constant stream of novel approaches to properly use these resources for genome-scale phylogenetic inference. New approaches can now leverage multicopy gene families, so that phylogenetic inference is no longer restricted to the tiny fraction of single-copy genes. Bayesian approaches to divergence estimation can now analyze genome-scale datasets and hundreds of taxa. However, systematic biases are always looming and can distort our understanding of species and gene relationships. Technical and analytical advances can provide new insights into the evolution of genes and species, but they are not always easy to master...