Ismail Can Karaoglu, Arda Odabas, Tamer Onder, Seda Kizilel* “Single-gene knockout of RNLS or HIVEP2 are insufficient to protect β-cell spheroids from allo- and xeno-rejection”, in press Frontiers in Immunology, Jan 2026. (AI voice summary 🔊, AI video summary 🎥 by Google NotebookLM)
Ismail Can Karaoglu "Multidisciplinary Approaches in Developing Immune-Evasive β-Cell Replacement Therapies for Type 1 Diabetes", Koç University, PhD Thesis, Aug 2025
Ismail Can Karaoglu, Dogukan Duymaz, Mudassir Rashid, Seda Kizilel* “Immune-Evasive Beta Cells in Type 1 Diabetes: Innovations in Genetic Engineering, Biomaterials, and Computational Modeling”, Frontiers in Immunology, Aug 2025. (AI voice summary 🔊, AI video summary 🎥 by Google NotebookLM)
Dogukan Duymaz, Ismail Can Karaoglu, Seda Kizilel* “Effect of Photoinitiation Process on Photo-Crosslinking of Gelatin Methacryloyl Hydrogel Networks”, Macromolecular Rapid Communications, July 2025.
Buğçe Aydın, Ö. Zeynep Güner-Yılmaz, Anıl Yılmaz, Sila Kilic, Ismail Can Karaoglu, Serdar Bozoglu, Özge Kurkcuoglu, Nilgün Karatepe and F. Seniha Güner* “Mitoxantrone Release from Fmoc-Protected Amino Acids Coated Magnetic Carbon Nanotubes: Computational and Experimental Study for Cancer Treatment”, Journal of Drug Delivery Science and Technology, Oct 2024.
Alican Kusoglu, Deniz Ornek, Asli Dansik, Ceren Uzun, Sena Nur Ozkan, Sevgi Sarica, Kardelen Yangin, Sevval Ozdinc, Duygu Turan Sorhun, Nuriye Solcan, Efe Can Doganalp, Øystein Arlov, Katherine Cunningham, Ismail Can Karaoglu, Seda Kizilel, Ihsan Solaroglu, Pinar Bulutay, Pinar Firat, Suat Erus, Serhan Tanju, Sukru Dilege, Gordana Vunjak-Novakovic, Nurcan Tuncbag, Ece Ozturk* "Extracellular matrix sulfation in the tumor microenvironment stimulates cancer stemness and invasiveness", Advanced Science, July 2024.
Sevval Ozdinc, Sevgi Sarıca, Sena N. Ozkan, Kardelen Yangin, Alican Kusoglu, Asli Dansik, Ismail Can Karaoglu, Seda Kizilel, Ece Ozturk* "Development and Characterization of Decellularized Lung Extracellular Matrix Hydrogels", Journal of Visualized Experiments, December 2023.
Ismail Can Karaoglu, Aybaran Olca Kebabci, Seda Kizilel* “Optimization of Gelatin Methacryloyl Hydrogel Properties through an Artificial Neural Network Model”, ACS Applied Materials & Interfaces, September 2023. (AI voice summary 🔊, AI video summary 🎥 by Google NotebookLM)
Ismail Can Karaoglu, Esra Yalcin, Ayesha Gulzar, Isilay Goktan, Seda Kizilel* “Hydrogels for 3D Frameworks” in Hydrogels: Fundamentals to Advanced Energy Applications, CRC Press, September 2023.
Selcan Karaz, Gizem Akay, Ismail Can Karaoglu, Mertcan Han, Sedat Nizamoglu, Seda Kizilel*, Erkan Senses* "Shear-Triggered Release of Lipid Nanoparticles from Tissue-Mimetic Hydrogels", Macromolecular Rapid Communications, April 2023.
Alican Kusoglu, Kardelen Yangin, Sena N. Ozkan, Sevgi Sarica, Deniz Ornek, Nuriye Solcan, Ismail Can Karaoglu, Seda Kizilel, Pinar Bulutay, Pinar Firat, Suat Erus, Serhan Tanju, Sukru Dilege, Ece Ozturk* "Characterization of Different Decellularization Methods in Bovine Lung Tissue Reveals Distinct Biochemical Composition, Stiffness and Viscoelasticity", ACS Applied Bio Materials, January 2023.
Tugba Bal+, Ismail Can Karaoglu+, Fusun Sevval Murat, Esra Yalcin, Yoshihiro Sasaki, Kazunari Akiyoshi, Seda Kizilel* “Immunological response of polysaccharide nanogel-incorporating PEG hydrogels in an in vivo diabetic model”, Journal of Biomaterials Science, Polymer Edition, May 2022. (+: equal authorship)
M. Anwaar Nazeer+, Ismail Can Karaoglu+, Onur Ozer, Cem Albayrak*, Seda Kizilel* “Neovascularization of engineered tissues for clinical translation: where we are, where we should be?” APL Bioengineering, April 2021. (+: equal authorship)
Koç University Teaching Assistant Award Oct, 2025
Koç University Academic Excellence Award Jun, 2025
Koç University Presidential Fellowship (~1500 $/month) Oct, 2024
Humboldt meets Leibniz Emerging Topics in Biomedical Engineering and Implant Research Sep, 2024
Travel and Accommodation scholarship
EFSUN Best Paper Award 2024, Sabancı University Aug, 2024
“Optimization of Gelatin Methacryloyl Hydrogel Properties through an Artificial Neural Network Model”, ACS Applied Materials & Interfaces,
September 2023. (1st out of 22 international finalist)
TUBITAK 2224 Grant Program for Participation in Scientific Meetings Abroad July, 2024
TUBITAK 2250 Graduate Scholarships Performance Program 2022 – 2024
TUBITAK 2211-A National PhD Scholarship Program June, 2021 – 2025
Koç University 2020 – 2025
Gradute scholarship
Istanbul Technical University-Chemical Engineering, High Honor Student June, 2020
Rank: 1st
TUBITAK 2209-A Support Program for University Students Research Projects June, 2018 – June, 2019
Istanbul Technical University-Molecular Biology and Genetics, High Honor Student June, 2019
Rank: 2nd
Mehmet Zorlu Vakfı 2014 – 2020
Undergradute scholarship
Chemical and Biological Engineering, Koc University
PhD candidate (GPA: 3.91)
Molecular Biology and Genetics, Istanbul Technical University
Undergradute student (2nd ranked, GPA: 3.69)
Chemical Engineering, Istanbul Technical University
Undergradute student (Double major, 1st ranked, GPA: 3.69)
Ismail Can Karaoglu "Designing immunologically invisible beta cell spheroids for the treatment of Type 1 Diabetes using biomaterials and genetic engineering", Humboldt meets Leibniz Emerging Topics in Biomedical Engineering and Implant Research, Hannover, Sep 2024
Ismail Can Karaoglu " Artificial Neural Network Modeling of Visible Light-induced Photo-crosslinking of GelMA Hydrogels ", KUTTAM 3rd Graduate Research Conference, Istanbul, Sep 2024
Ismail Can Karaoglu, Arda Odabas, T. Tamer Onder, Seda Kizilel "Designing immunologically invisible beta cell spheroids for the treatment of Type 1 Diabetes using biomaterials and genetic engineering", 11th National Biomaterials Congress at Ege University, Nov 2024
Nilufar Ismayilzada, Ecem Metin, Ismail Can Karaoglu, Seda Kizilel, Savas Tasoglu, Emel Sokullu "A three-dimensional micropatterned tumor model for glioblastoma migration studies", 21st National Neuroscience Congress at Abant İzzet Baysal University, June 2023
Rubab Batool, Ismail Can Karaoglu, F. Sevval Murat, M. Anwaar Nazeer, Seda Kizilel "Investigation of parameters influencing molecule delivery efficiency of Multifunctional Glycan-based materials: An artificial neural network model approach", 2021 MRS Fall Meeting, December 2021
Ayesha Gulzar, Rubab Batool, Ismail Can Karaoglu, F. Sevval Murat, M. Anwaar Nazeer, Afsun Sahin, Seda Kizilel "Immunological protection of dual crosslinked glycan-based hydrogels with TGF-β function", AIChE 6th Bioengineering & Translational Medicine Conference, October 2021.
Bugce Aydin, O. Zeynep Guner Yilmaz, Ismail Can Karaoglu, Serdar Bozoglu, Ozge Kurkcuoglu, Nilgun Yavuz, F. Seniha Guner “Mitoxantrone-Loaded Magnetic Single-Walled Carbon Nanotubes as Nanocarriers for Cancer Treatment”, Global Nanobiotechnology Consortium (GNC), March 2021.
Teaching Assistant, Chemical and Biological Engineering, Koc University (2020-present)
CHBI305-Heat and Mass Transfer (Fall, 2024)
CHBI491-Graduation Project (Spring, 2023)
CHBI305-Heat and Mass Transfer (Fall, 2022)
CHBI491-Graduation Project (Spring, 2022)
CHBI305-Heat and Mass Transfer (Fall, 2021)
CHBI584-Tissue Engineering (Spring, 2021)
CHBI305-Heat and Mass Transfer (Fall, 2020)
Student Laboratory Assistant, Mol. Bio. and Genetics, Istanbul Technical University (2015-2019)
BIO112E-General Biology Laboratory
BIO211E-Cell Biology Laboratory
BIO311E-Biochemistry Laboratory
BIO321E-Microbiology Laboratory
Laboratory Member in Microbial Ecology Laboratory, Ist. Tech. Univ. July, 2015 – Sep, 2016
PHA production from mix culture
Intern in Cerrahpasa Medical Faculty, Istanbul University June, 2016 – Sep, 2016
Determination of the relationship between SIRT6 expression and Type 2 Diabetes Mellitus
Intern in IONTEK Molecular Diagnosis, Istanbul June, 2017 – Sep, 2017
Determination and characterization of respiratory viruses in poultry
Development of detection kit for Hepatitis C Virus
Laboratory Member in Yeast Laboratory, Ist. Tech. Univ. Sep, 2017 – June,2019
Investigation of environmental stress response in S. cerevisiae by using inverse metabolic engineering
Intern in Helen Diller Family Comp. Cancer Center, University of California, San Francisco 2018 Summer
Co-targeting synthetic lethal interactions with eIF4E in cancer
Intern in BEYBO Boya Sanayi ve Ticaret AS July, 2019 – Aug, 2019
Factory Operation
Intern in DEVA Holding AS Aug, 2019 – Sep, 2019
Quality and Control Laboratory
TUBITAK COST Action (Project No:122S968) Feb, 2023 – Present
Investigation of the effect of knockout of HIVEP2 gene in insulin-secreting beta cells with CRISPR/Cas9 on immune acceptance and cell functionality in vivo
TUBITAK 1004 (Project No:20AG042) Oct, 2022 – Feb 2023
Development of Biomarkers and Advanced Technology Drugs for the Follow-up and Treatment of Inflammasome Mediated Auto-inflammatory Diseases
TUBITAK COST Action (Project No:119M171) Oct, 2020 – Oct, 2022
Light and pH Sensitive Anthracene Linked Functional Glycan Alginate Synthesis for Limbal Stem Cell Regeneration
TUBITAK 2209-A Support Program for University Students Research Projects June, 2018 – June, 2019
Investigation of the conformational changes in the yeast Hog1 protein during stress resistance by molecular dynamics simulations
Graduation Project (Molecular Biology and Genetics) Sep, 2018 – June, 2019
Investigation of cross-resistance profiles of diverse stress-resistant Saccharomyces cerevisiae strains
Graduation Project (Chemical Engineering) Sep, 2019 – June, 2020
Molecular dynamics simulations of drug-carbon nanotube system
Co-founder (Team'19) 2019
Advisor (Team '21) 2021
ITU Journal Club 2016
Founder
ITU Molecular Biology and Genetics Student Club 2015 – 2016
Vice President
ITU Orienteering Club 2014 – 2015
Member