Ventilator-associated pneumonia (VAP) is a major cause of morbidity and mortality in ventilated patients. It also has a major impact in terms of cost due to long and expensive treatment needed. 

"The VAP reduction care bundle is a grouping of evidence-based high impact interventions. In its original form, it was an early example of the Institute for Healthcare Improvement (IHI) care bundle methodology in the US."

Adapted from NHS, Critical Care Network, North West London