Publications & AWARDS

Peer-review research articles (Published or Under review) ( †Co-first author)

1. Ruei-Jyun Hung, Intan Low, Hung-Chun Yeh, Po-Yu Wang, Yong-Sheng Chen, Li-Fen Chen* (under review). Feedback matters: EEG correlates of empathy involved in the naturalistic communication of emotions. Brain Research (under review). [SCIE, IF=2.9, RF=0.64 (174/272), NEUROSCIENCES]

2. Lin-Chien Lee, Ya-Yun Chen, Wei-Chi Li, Ching-Ju Yang, Ching-Hsiung Liu, Intan Low, Hsiang-Tai Chao, Li-Fen Chen, and Jen-Chuen Hsieh (2023). Adaptive neuroplasticity in the default mode network contributing to absence of central sensitization in primary dysmenorrhea. Frontiers in Neuroscience, 17, 144. [SCIE, IF=4.3, RF=0.346 (94/272), NEUROSCIENCES]

3. Chun-Chih Huang, Intan Low, Chia-Hsiang Kao, Chuan-Yu Yu, Tung-Ping Su, Jen-Chuen Hsieh, Yong-Sheng Chen, Li-Fen Chen* (2022). MEG-based classification and Grad-CAM visualization for major depressive and bipolar disorders with Semi-CNN. 2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (IEEE EMBC), 2022:1823-1826. (Cited: 1)

4. Wei-Yang Yu†, Intan Low†, Chien Chen, Jong-Ling Fuh*, Li-Fen Chen* (2021). Brain dynamics altered by photic stimulation in patients with Alzheimer’s disease and mild cognitive impairment. Entropy, 23(4):427. [SCIE, IF=2.7, RF=0.47 (40/85), PHYSICS, MULTIDISCIPLINARY] (Cited: 7)

5. Hui-Ling Chan*†, Intan Low†, Li-Fen Chen, Yong-Sheng Chen, Jen-Chuen Hsieh* (2021). A novel beamformer-based imaging of phase-amplitude coupling (BIPAC) unveiling the inter-regional connectivity of emotional prosody processing in women with primary dysmenorrhea. Journal of Neural Engineering, 18:046074 [SCIE, IF=4.0, RF=0.386 (105/272), NEUROSCIENCES] (Cited: 4)

6. Intan Low, Po-Chih Kuo, Cheng-Lin Tsai, Yu-Hsiang Liu, Ming-Wei Lin, Hsiang-Tai Chao, Yong-Sheng Chen, Jen-Chuen Hsieh*, and Li-Fen Chen* (2018). Interactions of BDNF Val66Met polymorphism and menstrual pain on brain complexity. Frontiers in Neuroscience, 12:826. [SCIE, IF=4.3, RF=0.346 (94/272), NEUROSCIENCES] (Cited: 11)

7. Lin-Chien Lee, Yueh-Hua Chen, Chia-Shu Lin, Wei-Chi Li, Intan Low, Cheng-Hao Tu, Chih-Che Chou, Chou-Ming Cheng, Tzu-Chen Yeh, Li-Fen Chen, Hsiang-Tai Chao, and Jen-Chuen Hsieh* (2018). Unaltered intrinsic functional brain architecture in young women with primary dysmenorrhea. Scientific Reports, 8:12971. [SCIE, IF=4.6, RF=0.301 (22/73), MULTIDISCIPLINARY SCIENCES] (Cited: 14)

8. Intan Low, Po-Chih Kuo, Yu-Hsiang Liu, Cheng-Lin Tsai, Hsiang-Tai Chao, Jen-Chuen Hsieh, Li-Fen Chen*, Yong-Sheng Chen* (2017). Altered brain complexity in women with primary dysmenorrhea: a resting-state MEG study using multiscale entropy analysis. Entropy, 19(12):680. [SCIE, IF=2.7, RF=0.47 (40/85), PHYSICS, MULTIDISCIPLINARY] (Cited: 14)

9. Pin-Shiuan Lee, Intan Low, Yong-Sheng Chen, Cheng-Hao Tu, Hsiang-Tai Chao, Jen-Chuen Hsieh*, Li-Fen Chen* (2017). Encoding of menstrual pain experience with theta oscillations in women with primary dysmenorrhea. Scientific Reports, 7:15977. [SCIE, IF=4.6, RF=0.301 (22/73), MULTIDISCIPLINARY SCIENCES] (Cited: 21)

10. Shyh-Yuh Wei, Li-Fen Chen, Ming-Wei Lin, Wei-Chi Li, Intan Low, Ching-Ju Yang, Hsiang-Tai Chao, Jen-Chuen Hsieh* (2017). The OPRM1 A118G polymorphism modulates the descending pain modulatory system for individual pain experience. Scientific Reports, 7:39906. [SCIE, IF=4.6, RF=0.301 (22/73), MULTIDISCIPLINARY SCIENCES] (Cited: 37)

11. Ting-Hsuan Wu, Cheng-Hao Tu, Hsiang-Tai Chao, Wei-Chi Li, Intan Low, Chih-Ying Chuang, Tzu-Chen Yeh, Chou-Ming Cheng, Chih-Che Chou, Li-Fen Chen*, Jen-Chuen Hsieh* (2016). Dynamic Changes of Functional Pain Connectome in Women with Primary Dysmenorrhea. Scientific Reports, 6:24543. [SCIE, IF=4.6, RF=0.301 (22/73), MULTIDISCIPLINARY SCIENCES] (Cited: 63)

12. Shyh-Yuh Wei, Hsiang-Tai Chao, Cheng-Hao Tu, Ming-Wei Lin, Wei-Chi Li, Intan Low, Horng-Der Shen, Li-Fen Chen*, Jen-Chuen Hsieh* (2016). The BDNF Val66Met polymorphism is associated with the functional connectivity dynamics of pain modulatory systems in primary dysmenorrhea. Scientific Reports, 24(6):23639. [SCIE, IF=4.6, RF=0.301 (22/73), MULTIDISCIPLINARY SCIENCES] (Cited: 35)

13. Shyh-Yuh Wei, Hsiang-Tai Chao, Cheng-Hao Tu, Wei-Chi Li, Intan Low, Chih-Ying Chuang, Li-Fen Chen*, Jen-Chuen Hsieh* (2016). Changes in functional connectivity of pain modulatory systems in women with primary dysmenorrhea. Pain, 157: 92–102. [SCIE, IF=7.4, RF=0.09 (19/212), CLINICAL NEUROLOGY] (Cited: 97) 

In preparation ( †Co-first author )

1. Intan Low, Yen-Liang Liu, Yi-Chen Lee, Li-Jen Hung, Chiao-Yun Lee, Yueh-Hsin Ping, Jiing-Feng Lirng, Li-Fen Chen*, Chen-Huan Chen*. Ten-year outcomes and challenges of Taiwan’s first long-term physician-scientist cultivation program: A mixed-method, retrospective study.

2.  Intan Low†, Fei-Pi Lan†, Chih-Che Chou, Li-Fen Chen*, and Jen-Chuen Hsieh*. Effects of transcranial direct current stimulation on brain complexity in women with primary dysmenorrhea: a resting-state MEG study.

3. Kuang-Chuan Chu, Yen-Hsun Huang, Tzu-Fu Lin, Jiun-Wei Chen, Intan Low*, Li-Fen Chen*. Effects of dance training on cognitive function and interpersonal interaction of the elderly: An EEG study.

4. Intan Low†, Tzu-Fu Lin†, Ruei-Jyun Hung, Han-Kuei Fu, Hsin-Yu Li, Wei-Yang Yu, Jen-Chuen Hsieh*, Li-Fen Chen*. Association of auditory-entrained brain complexity with pain.

5. Intan Low†, Meng-Hung Lee†, Pin-Shiuan Lee, Fang-I Wu, Ruei-Jun Hung, Yong-Sheng Chen, Li-Fen Chen*. The effect of music listening on anxiety reduction: Quantitative assessments using MEG signals and deep learning approach.

• Intan Low, Shyh-Yuh Wei, Pin-Shiuan Lee, Wei-Chi Li, Lin-Chien Lee, Jen-Chuen Hsieh*, Li-Fen Chen* (2018, Oct). Neuroimaging Studies of Primary Dysmenorrhea. In Shyu BC., Tominaga M. (eds) Advances in Pain Research: Mechanisms and Modulation of Chronic Pain. Advances in Experimental Medicine and Biology, vol 1099, 179-199. Springer, Singapore.

1. Chun-Chih Huang, Intan Low, Tung-Ping Su, Jen-Chuen Hsieh, Yong-Sheng Chen*, Li-Fen Chen. Subject-independent classification for major depressive disorder using resting-state MEG signals. 2024 IWAIT Proceedings of SPIE (abstract accepted), Langkawi, Malaysia, Jan 7-8, 2024. [EI]

2. Intan Low, Yen-Liang Liu, Yi-Chen Lee, Li-Jen Hung, Chiao-Yun Lee, Yueh-Hsin Ping, Jiing-Feng Lirng, Li-Fen Chen*, Chen-Huan Chen*. A brief overview of the 10-year outcomes and challenges from Taiwan’s first long-term physician-scientist cultivation program: A mixed-method, retrospective study. First prize in oral presentation contest at the 2023 International Symposium of Medical Education at Taipei Veterans General Hospital, Taipei, Taiwan, Nov 17, 2023.

3. Intan Low, Fei-Pi Lan, Chih-Cher Chou, Wei-Chi Li, Chou-Ming Cheng, Hsiang-Tai Chao, Jen-Chuen Hsieh, Li-Fen Chen*. Effects of transcranial direct current stimulation on altered brain complexity in women with primary dysmenorrhea: a resting-state MEG study. Poster presented at the 27th Annual Meeting of the Organization for Human Brain Mapping (OHBM 2023), Montréal, Canada, Jul 22-26, 2023.

4. Intan Low, Li-Jen Hung, Jia-Ying Li, Chen-Huan Chen*, Li-Fen Chen*. Outcome evaluation for physician-scientist cultivation: Insights from a 10-year program in Taiwan. ePoster to be presented at the 2022 Conference of Association for Medical Education in Europe (AMEE 2022), Lyon, France (Hybrid conference), Aug 27-31, 2022.

5. Chun-Chih Huang, Intan Low, Chia-Hsiang Kao, Chuan-Yu Yu, Tung-Ping Su, Jen-Chuen Hsieh, Yong-Sheng Chen, Li-Fen Chen*. MEG-based classification and GRAD-CAM visualization for major depressive and bipolar disorders with semi-CNN. Oral presentation at the 2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (IEEE EMBC), Scotland, UK, July 11-15, 2022.

6. Fei-Pi Lan, Chih-Che Chou, Intan Low, Li-Fen Chen*, Jen-Chuen Hsieh*. Effects of transcranial direct current stimulation on altered brain complexity in women with primary dysmenorrhea: a resting-state MEG study. The Honorable Mention Award, Poster presented at the 2022 Annual Academia Poster Seminar, National Yang Ming Chiao Tung University, Taipei, Taiwan, Jun 9, 2022.

7. Chun-Chih Huang, Intan Low, Chia-Hsiang Kao, Chuan-Yu Yu, Tung-Ping Su, Jen-Chuen Hsieh, Yong-Sheng Chen, Li-Fen Chen*. MEG-based classification and Grad-CAM visualization for major depressive and bipolar disorders with semi-CNN. Poster presented at the 2022 Annual Academia Poster Seminar, National Yang Ming Chiao Tung University, Taipei, Taiwan, Jun 9, 2022.

8. Hung-Chun Yeh, Ruei-Jyun Hung, Intan Low, Pei-Chun Chang, Tzu-Ching Wang, Po-Yu wang, Yong-Sheng Chen, Li-Fen Chen*. Brain-to-brain synchrony during emotional speech communication. Poster presented at the 2022 Annual Academia Poster Seminar, National Yang Ming Chiao Tung University, Taipei, Taiwan, Jun 9, 2022.

9. Intan Low*, Tzu-Fu Lin, Li-Fen Chen*, Chen-Huan Chen. Evaluating the outcomes and challenges of physician-scientist cultivation: a preliminary scoping review. The High Distinction Award, Online poster presented at the 2021 International Symposium of Medical Education at Taipei Veterans General Hospital, Taipei, Taiwan, Oct 15-16, 2021.

10. Intan Low, Ian-Ting Chu, Wei-Chi Li, Hsiang-Tai Chao, Hong-Der Shen, Jen-Chuen Hsieh*, and Li-Fen Chen*. Long-term menstrual pain modulates brain activities underlying vocal emotion perception. IASP 2021 Virtual World Congress on Pain, Jun 9-11 and 16-18, 2021

11. Chia-Wei Chang, Chun-Chih Huang, Pin-Shiuan Lee, Intan Low, Cheng-Ta Li, Tung-Ping Su, Jen-Chuen Hsieh, Li-Fen Chen*. A machine learning based approach for prediction of rTMS treatment response in patients with drug-resistant depression using magnetoencephalographic data. Online poster presented at the 13th International Science Youth Forum Digital (ISYF digital 2021), Singapore (Digital Forum), Jan 19-22, 2021.

12. Chun-Chih Huang, Chuan-Yu Yu, Intan Low, Tung-Ping Su, Jen-Chuen Hsieh, Li-Fen Chen*. Using deep learning techniques to classify major depressive disorder and bipolar disorder based on MEG signals. The 1st Taiwan Society for Neuroscience (TSfN) Meeting, Academia Sinica, Taipei, Taiwan, Sep 11-13, 2020

13. Min-Chun Tsai, Hsin-Yuan Chang, Ya-Lin Huang, Hsi-Yang Hung, Intan Low, Chun-Chih Huang, Chuan-Yu Yu, Tung-Ping Su, Jen-Chuen Hsieh, Li-Fen Chen, Chun-Shu Wei*. Covariance Representation Analysis (CRA): An automatic tool for quality assessment of large-scale EEG/MEG data. The 1st Taiwan Society for Neuroscience (TSfN) Meeting, Academia Sinica, Taipei, Taiwan, Sep 11-13, 2020

14. Jiun-Wei Chen, Intan Low, Li-Kai Cheng, Hui-Ling Chan, Hsin-Yen Yu, Yong-Sheng Chen, Jen-Chuen Hsieh, Li-Fen Chen* (2020). Dynamic imaging of phase-amplitude coupling during rhythm processing in percussionists. The 26th Annual Meeting of the Organization for Human Brain Mapping (Virtual conference, OHBM), Jun 23-Jul 3, 2020

15. Tzu-Fu Lin, Intan Low, Ruei-Jyun Hung, Jen-Chuen Hsieh*, Li-Fen Chen* (2020). Brain dynamics changes induced by auditory alpha entrainment for pain modulation. The 2020 Annual Academia Poster Seminar, National Yang-Ming University, Taipei, Taiwan, Jun 11, 2020

16. Wei-Yang Yu, Li-Fen Chen*, Intan Low, Chien Chen, Jong-Ling Fuh (2020). Brain dynamics induced by photic stimulation in Alzheimer’s disease and mild cognitive impairment patients. The 2020 Annual Academia Poster Seminar, National Yang-Ming University, Taipei, Taiwan, Jun 11, 2020

17. Ruei-Jyun Hung, Intan Low, Tzu-Fu Lin, Han-Kui Fu, Hsin-Yu Li, Li-Fen Chen, Jen-Chuen Hsieh* (2019). Modulating pain by auditory neural entrainment. Neuroscience 2019 (by Society for Neuroscience), Chicago, USA, Oct 19-23, 2019

18. Fang-Yi Wu, Meng-Hong Lee, Intan Low, Li-Fen Chen* (2019). Effects of music listening on pain-induced anxiety: an MEG study. The 2019 Annual Academia Poster Seminar, National Yang-Ming University, Taipei, Taiwan, June 13, 2019

19. Intan Low, Po-Chih Kuo, Cheng-Lin Tsai, Yu-Hsiang Liu, Ming-Wei Lin, Hsiang-Tai Chao, Yong-Sheng Chen, Jen-Chuen Hsieh*, and Li-Fen Chen* (2018). Interactions between long-term menstrual pain and BDNF Val66Met polymorphism on brain complexity. The 17th World Congress on Pain (WCP 2018), Boston, USA, Sep 12-16, 2018

20. Intan Low, Po-Chih Kuo, Yu-Hsiang Liu, Cheng-Lin Tsai, Hsiang-Tai Chao, Jen-Chuen Hsieh, Li-Fen Chen*, Yong-Sheng Chen* (2017). Altered brain complexity in women with primary dysmenorrhea: a resting-state MEG study using multiscale entropy analysis. The 2nd International Conference on Biomedical Signal and Bioinformatics (ICBSB 2017), Auckland, New Zealand, November 27-30, 2017

21. Intan Low*, Wei-Chi Li, Hsiang-Tai Chao, Jen-Chuen Hsieh, Li-Fen Chen (2017). Modulation of early emotional processing by menstrual pain in primary dysmenorrhea: an MEG study. The 11th International Conference on Cognitive Science (ICCS 2017), Taipei, Taiwan, September 1-3, 2017

22. Intan Low*, Wei-Chi Li, Hsiang-Tai Chao, Jen-Chuen Hsieh, and Li-Fen Chen* (2017). State- and trait-alterations of emotional responses in primary dysmenorrhea: an MEG study. The 2017 Annual Academia Poster Seminar, National Yang-Ming University, Taipei, Taiwan, June 8, 2017

23. Intan Low*, Wei-Chi Li, Hsiang-Tai Chao, Jen-Chuen Hsieh, Li-Fen Chen* (2017). Long-term menstrual pain modulates emotional perception in primary dysmenorrhea women: an MEG study. The 2017 Annual Meeting of Taiwan Society of Cognitive Neuroscience (TSCN), Taoyuan, Taiwan, January 21, 2017

24. Intan Low*, Wei-Chi Li, Hsiang-Tai Chao, Jen-Chuen Hsieh, and Li-Fen Chen* (2016). Changes of emotional processing in women with primary dysmenorrhea after long-term menstrual pain: an MEG study. The 20th International Conference on Biomagnetism (BIOMAG2016), Seoul, Korea, October 1-6,2016

25. Intan Low, Wei-Chi Li, Hsiang-Tai Chao, Jen-Chuen Hsieh, and Li-Fen Chen* (2016). Decreased theta responses to emotional prosody in women with primary dysmenorrhea. The Excellence Award, 2016 Annual Academia Poster Seminar, National Yang-Ming University, Taipei, Taiwan, June 7, 2016

26. Intan Low, Yu-Hsiang Liu, Cheng-Hao Tu, Hsiang-Tai Chao, Jen-Chuen Hsieh, Li-Fen Chen* (2014). Long-term cyclic menstrual pain changes emotional prosody processing in primary dysmenorrhea females. The 19th International Conference on Biomagnetism (BIOMAG2014), Halifax, Nova Scotia, Canada, August 24-28, 2014

27. Li-Fen Chen, Yu-Hsiang Liu, Intan Low, Cheng-Hao Tu, Hsiang‐Tai Chao, Ming‐Wei Lin, Jen‐Chuen Hsieh (2014). Effects of BDNF Val66Met polymorphism on neural responses to emotional prosody in dysmenorrhea: a MEG study. The 11th International Imaging Genetics Conference, UC Irvine, CA, USA, Jan 19-20, 2014

28. Li-Fen Chen*, Yu-Hsiang Liu, Intan Low, Cheng-Hao Tu, Hsiang‐Tai Chao, Ming‐Wei Lin, Jen‐Chuen Hsieh (2014). Effects of BDNF Val66Met polymorphism on neural responses to emotional prosody in dysmenorrhea: a MEG study. The 2014 Annual Meeting of Taiwan Society of Cognitive Neuroscience, Jhongli, Taiwan, Jan 18, 2014

29. Lin-Chien Lee, Li-Fen Chen, Intan Low, Cheng-Hao Tu, Horng-Der Shen, Hsiang-Tai Chao, Ming-Wei Lin, Jen-Chuen Hsieh* (2013). Brain-derived neurotrophic factor Val66Met polymorphism modulates the menstrual pain related depressive and anxious moods in primary dysmenorrhea. The 24th Annual Scientific Meeting of Taiwan Pain Society, Taipei, Taiwan, March 9-10, 2013

30. 金榮泰、陳巧雲、劉盈丹、洪蘭。「受限制的情感刺激與擋不住的誘惑在腦中的處理歷程」。2005年台灣心理學年會壁報。

Science Writing

• 「變性無罪 平權有理─變性慾者的腦內乾坤」。陽明電子報，2015/5/30出刊。

Science Video Translation

• California Academy of Sciences (2016, January 11). Think Before You Eat - How Your Food Choices Can Save the Environment. Retrieved from https://www.youtube.com/watch?v=yaiAEvPImYw 繁體中文譯者 (2016)。三思而後食：你的飲食選擇能如何拯救環境。