Day 1 - Wednesday
Check-in (3:00 - 6:00 PM)
You will get your badge on check-in, there is no other on-site registration
Please put up your posters in the Bay Room before the evening session
5:00 - 6:00 PM
Dinner (Granhall) 6:00 - 7:30
7:30 - 7:45 PM
7:45 - 8:45 PM
Title: CryoEM and CryoET: Tools and Technologies from Origins to Outlook
Founding Technical Director
Chan Zuckerberg Imaging Institute
Social/Cash Bar (Cedar House) 8:45 - 11:00 PM
Day 2 - Thursday
Breakfast (Granhall) 7:00 - 8:00
Session 1 (Mountain Lake)
In vitro Compositional and Conformational Variability
8:00 - 8:15 AM
8:15 - 8:35 AM
The Inaugural Flatiron Institute Cryo-EM Conformational Heterogeneity Challenge
Flatiron Institute
8:40 - 9:00 AM
On a Flaw in EM
Yale University
9:05 - 9:25 AM
Identifying thermodynamically distinct structural states and their transition pathways from cryo-EM data using a deep isometric autoencoder
Graduate School of Medicine, Kyoto University
9:30 - 9:50 AM
Resolving structural heterogeneity in complex mixtures
MIT
Coffee Break 10:00 - 10:20 AM
Session 2 (Mountain Lake)
In situ Compositional and Conformational Variability
10:20 - 10:35 AM
10:35 - 10:55 AM
AI Methods for High-Throughput Biomolecular Structure Determination in Cryo-ET
Princeton University, Princeton, NJ, USA
11:00 - 11:20 AM
Studying structure heterogeneity in-situ using nextPYP
Duke University, Durham, NC, USA
11:25 - 11:45 AM
PyTom-match-pick integrated into pipeline for structure determination in situ
Utrecht University, Utrecht, Netherlands
11:50 - 12:10 AM
Quantification of membrane structures from cryo-EM micrographs and tomograms
Forschungszentrum Jülich, Jülich, Germany
Lunch (Granhall) 12:15 - 1:15
Afternoon Free Until Posters
4:00 - 6:00 PM
Wine and Cheese Reception (Bay Room)
Dinner (Granhall) 6:00 - 7:30
Session 3 (Mountain Lake)
Automation
7:30 - 7:45 PM
7:45 - 8:05 PM
Need for speed: cryo-plasma focused ion beam milling on the road to a high-throughput cryo-electron tomography pipeline
Max Planck Institute of Molecular Physiology, Dortmund Germany
8:10 - 8:30 PM
Advancing cryo-EM throughput and performance
The University of Tokyo, Tokyo Japan
8:35 - 8:55PM
Dr. Bonnie Murphy
Development of elemental mapping for cryo-EM
Max Planck Institute of Biophysics, Frankfurt am Main, Germany
9:00 - 9:20 PM
The next generation of open source software platform for cryo-FIBSEM: The crossover from SerialFIB and OpenFIBSEM to the fibsemOS platform
Max Planck Institute of Biochemstry, Martinsried, Munich
Social Hour/Cash Bar (Cedar House) 9:30 - 11:00 PM
Day 3 - Friday
Breakfast (Granhall) 7:00 - 8:00
Session 4 (Mountain Lake)
Modeling & Validation in CryoEM/ET
8:00 - 8:15 AM
8:15 - 8:35 AM
Interpreting small molecule ligand binding in cryoEM densities
Dept of Integrative Structural and Computational Biology, Scripps Research and Dept of Structural Biology, Bristol Myers Squibb
8:40 - 9:00 AM
New Methods for Evaluating Resolution Anisotropy
Dept. of Radiology and Biomedical Imaging, Yale University.
9:05 - 9:25 AM
Deep Learning Approaches to Building Protein Structures from Cryo-EM Maps and AlphaFold Predictions
Department of Electrical Engineering and Computer Science, NextGen Precision Health, University of Missouri, Columbia, MO, USA
9:30 - 9:50 AM
Confidence-weighted and context-aware cryoEM map optimisation
Kavli Institute of Nanoscience Delft & Delft University of Technology (The Netherlands)
Group Photo 10:00 - 10:10
Coffee Break 10:10 - 10:20 AM
Selected Posters Posted
If you have a poster, CHECK THE SCREEN
Session 5 (Mountain Lake)
Tomogram Segmentation and Interpretation
10:20 - 10:35 AM
10:35 - 10:55 AM
Uncovering Protein Domains at Intermediate Resolution
McGill University (Canada)
11:00 - 11:20 AM
Geometric Approaches for Tilt-Series Refinement in STOPGAP
Vanderbilt University
11:25 - 11:45 AM
Towards Automated cryo-ET: Self-supervised Tomogram Reconstruction and Promptable Particle Picking
Technical University Munich (Germany)
11:50 - 12:10 AM
Redefining cryo-ET Data Mining as an Integrative Structural Modeling Problem.
Centre for Structural Systems Biology (Germany)
Lunch (Granhall) 12:15 - 1:15
Afternoon Free Until Posters
Wine and Cheese Reception (Bay Room) 4:00 - 6:00
4:00 - 5:15 PM
5:15 - 6:00 PM
Masahide Kikkawa (Chair)
Panelists
Dinner (Granhall) 6:00 - 7:30
Session 6 (Mountain Lake)
Selected Poster talks
7:30 - 9:30
Selected poster talks, each 10 min + 5 for questions
Social Hour/Cash Bar (Cedar House) 9:30 - 11:00 PM
Saturday - Departures
Breakfast (Granhall) 7:00 - 8:00
Check Out - Departures