Day 1 - Wednesday
Check-in (3:00 - 6:00 PM)
You will get your badge on check-in, there is no other on-site registration
Please put up your posters in the Bay Room before the evening session
No photography of scientific content is permitted during the sessions. The organizers will take photos which don't compromise this intent and share them.
5:00 - 6:00 PM
Dinner (Granhall) 6:00 - 7:30
7:30 - 7:45 PM
7:45 - 8:45 PM
Title: CryoEM and CryoET: Tools and Technologies from Origins to Outlook
Founding Technical Director
Chan Zuckerberg Imaging Institute
7:45 - 8:45 PM
Round Table - Deep learning impact on community innovation
Masahide Kikkawa (Chair)
Panelists:
Jianlin Cheng, University of Missouri
Reinhard Heckel, Tecnical Univesity of Munich
Alberto Bartesaghi, Duke University
Social/Cash Bar (Cedar House) 8:45 - 11:00 PM
Day 2 - Thursday
Breakfast (Granhall) 7:00 - 8:00
Session 1 (Mountain Lake)
In vitro Compositional and Conformational Variability
8:00 - 8:15 AM
8:15 - 8:35 AM
The Inaugural Flatiron Institute Cryo-EM Conformational Heterogeneity Challenge
Flatiron Institute
8:40 - 9:00 AM
On a Flaw in EM
Yale University
9:05 - 9:25 AM
Identifying thermodynamically distinct structural states and their transition pathways from cryo-EM data using a deep isometric autoencoder
Graduate School of Medicine, Kyoto University
9:30 - 9:50 AM
Resolving structural heterogeneity in complex mixtures
MIT
Coffee Break 10:00 - 10:30 AM
Session 2 (Mountain Lake)
In situ Compositional and Conformational Variability
10:30 - 10:40 AM
10:45 - 11:05 AM
Studying structure heterogeneity in-situ using nextPYP
Duke University, Durham, NC, USA
11:10 - 11:30 AM
PyTom-match-pick integrated into pipeline for structure determination in situ
Utrecht University, Utrecht, Netherlands
11:35 - 11:45 AM
Synthetic Data-Driven Deep Learning for Robust Membrane Segmentation in Cryo-Electron Tomography
TFS (Vendor short talk)
11:50 - 12:10 PM
Quantification of membrane structures from cryo-EM micrographs and tomograms
Forschungszentrum Jülich, Jülich, Germany
Lunch (Granhall) 12:15 - 1:15
Afternoon Free Until Posters
4:00 - 6:00 PM
Wine and Cheese Reception (Bay Room)
Dinner (Granhall) 6:00 - 7:30
Session 3 (Mountain Lake)
Automation
7:30 - 7:45 PM
7:45 - 8:05 PM
Need for speed: cryo-plasma focused ion beam milling on the road to a high-throughput cryo-electron tomography pipeline
Max Planck Institute of Molecular Physiology, Dortmund Germany
8:10 - 8:30 PM
Advancing cryo-EM throughput and performance
The University of Tokyo, Tokyo Japan
8:35 - 8:55 PM
GoToCloud: optimization of cloud computing environments for accelerating cryo-EM structure-based drug design
High Energy Accelerator Research Organization (KEK), University of Tsukuba, Ibaraki, Japan
Social Hour/Cash Bar (Cedar House) 9:00 - 11:00 PM
Day 3 - Friday
Breakfast (Granhall) 7:00 - 8:00
Session 4 (Mountain Lake)
Modeling & Validation in CryoEM/ET
8:00 - 8:15 AM
8:15 - 8:35 AM
Q-score as a validation metric for 3DEM maps and models
Department of Bioengineering, Stanford University
8:40 - 9:00 AM
New Methods for Evaluating Resolution Anisotropy
Dept. of Radiology and Biomedical Imaging, Yale University.
9:05 - 9:25 AM
Deep Learning Approaches to Building Protein Structures from Cryo-EM Maps and AlphaFold Predictions
Department of Electrical Engineering and Computer Science, NextGen Precision Health, University of Missouri, Columbia, MO, USA
9:30 - 9:50 AM
Confidence-weighted and context-aware cryoEM map optimisation
Kavli Institute of Nanoscience Delft & Delft University of Technology (The Netherlands)
Group Photo 10:00 - 10:10
(PLEASE, no coffee outside in the photo!)
Coffee Break 10:10 - 10:30 AM
Selected Posters Posted
If you have a poster, CHECK THE SCREEN
Session 5 (Mountain Lake)
Tomogram Segmentation and Interpretation
10:30 - 10:45 AM
10:45 - 11:05 AM
Uncovering Protein Domains at Intermediate Resolution
McGill University (Canada)
11:10 - 11:30 AM
Geometric Approaches for Tilt-Series Refinement in STOPGAP
Vanderbilt University
11:35 - 11:55 PM
Towards Automated cryo-ET: Self-supervised Tomogram Reconstruction and Promptable Particle Picking
Technical University Munich (Germany)
12:00 - 12:20 AM
Modeling of macromolecular-membrane systems from cryo-ET data
European Molecular Biology Laboratory (EMBL), Hamburg (Germany)
Lunch (Granhall) 12:20 - 1:20
Afternoon Free Until Posters
Wine and Cheese Reception (Bay Room) 4:00 - 6:00
4:00 - 6:00 PM
4:00 - 5:00 PM
Vendors' Session (Mountain Lake)
Advances in cryo-ET and data visualization (Dr. Eliza Nieweglowska and Dr. Mark McClendon, TFS)
The JEOL cryoARM for High-Throughput Cryo-EM (Dr. Emmanuel W. Smith, JEOL).
Dinner (Granhall) 6:00 - 7:30
Session 6 (Mountain Lake)
Selected Poster talks
7:30 - 9:30
Selected poster talks, each 10 min + 5 for questions
Anya Porter
Jessie T. Zhang
Jiahua He
Laina N Hall
Marten Chaillet
Raison Dsouza
Sheng Xu
Social Hour/Cash Bar (Cedar House) 9:30 - 11:00 PM
Saturday - Departures
Breakfast (Granhall) 7:00 - 8:00
Check Out - Departures