Scientific program
(Program will be updated by presentations of registered participants)
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Thursday May 31, 2018
9:00 – 9:30: Introductory and welcome address
Marc Diederich, College of Pharmacy, SNU, Local organizer
Hee Young Shin, Vice President of Research, SNU
Bong-Jin Lee, Dean, College of Pharmacy, SNU
Young-Joon Surh, Director of TuMeR, College of Pharmacy, SNU
Zahra Zakeri, President ICDS, Queens College of the City University of New York, USA
9:30 – 10:30 Award lecture (Chair: Zahra Zakeri)
Richard Lockshin (Queens College of the City University of New York, USA)
J. Marie Hardwick (Pharmacology and Molecular Biology, Johns Hopkins School of Medicine, USA)
The death of pathogenic fungi
10:30 – 11:00: Coffee break
Session 1: Immune-mediated cell death mechanisms (Chair: Sarit Larisch)
11:00 – 11:30: Luis Alberto Baena-Lopez (University of Oxford, UK)
Unknown biological features of caspase-activating cells uncovered by novel apical caspase reporters
11:30 – 12:00: Jerry Edward Chipuk (Icahn School of Medicine at Mount Sinai, New York, USA) MDM2 integrates cellular respiration and apoptotic signaling through NDUFS1 and the mitochondrial network
12:00 - 12:30: Marie-Lise Gougeon (Institut Pasteur, Paris, France)
Innate immunity and viral persistence; contribution of alarmins
12:30 – 13:00: Hyunah Lee (R&D Center, Pharmicell Co., South Korea)
Induction of immunogenic cell death of tumors by newly synthesized heterocyclic quinone derivatives
13:00 – 14:00: Lunch break
Session 2: Necroptotic cell death pathways (Chair: Marianne Cronje)
14:00 – 15:00: Peter Vandenabeele (VIB, Department for Molecular Biomedical Research, Ghent, Belgium): Molecular mechanisms of necroptosis execution
15:00 – 15:30: Seamus J. Martin (Molecular Cell Biology Laboratory, The University of Dublin, Ireland): An Inflammatory Perspective on Necroptosis
15:30 – 16:00: Eun-Woo Lee (Korea Research Institute of Bioscience & Biotechnology (KRIBB), Daejeon, South Korea): Post-translational control of RIPK3 in necroptosis
16:00 – 16:30: Coffee break
Session 3: Cell death pathways I (Chair: Samuel Katz)
16:30 – 17:00: Barbora Boyer-Orlikova (College of Pharmacy, Seoul National University, South Korea): PARP-1 dependent-like cell death induced by indolequinones in human leukemia
17:00 – 17:20: Sander Bekeschus (Leibniz‑Institute for Plasma Science and Technology, Greifswald, Germany) Reactive Species in Immunogenic Cancer Cell Death
17:20 - 17:40: Seung-Ju Cho (College of Pharmacy, Seoul National University, Korea)
Selective elimination of culture-adapted human embryonic stem cells with BH3 mimetic
17:40 – 18:00: David Calianese (Rutgers, Biomedical and Health Sciences, Newark, USA)
Targeting Phosphatidylserine/TAM receptor/PD-L1 axis as a vulnerability in cancer
18:00 – 18:20: Myeong-Gyun Kang (Ulsan National Institute of Science and Technology (UNIST), Korea) Spatiotemporal proximity crosslinking by light activation (Spot-light) reveals RNA processing machinery on the mitochondria in live cells
18:30 - 19:30: Welcome reception
Friday June 1st, 2018
Session 4: Cell death pathways II (Chair: Raymond Birge)
9:00 – 9:30: Eli Arama (Weizmann Institute of Science, Israel): There is More than One Way to Die: A DNase II-Dependent Cell Death Program in Drosophila
9:30 – 10:00: Kyeong Sook Choi (Ajou University, South Korea): Paraptosis in the anti-cancer arsenal of natural products
10:00 – 10:30: Hun Taeg Chung (University of Ulsan, Republic of Korea)
Carbon Monoxide Ameliorates Acute Hepatitis-Mediated Liver Injury through the Autophagy/Lysosomal Pathway
10:30 – 11:00: Coffee break
Session 5: Cell death pathways III (Chair: Michael Schnekenburger)
11:00 – 11:30: Tugba Bagci (Molecular Biology and Genetics, Koc Univ. School of Medicine, Turkey): Loss of function screens to interrogate mechanisms of chemotherapy resistance in cancers
11:30 – 12:00: Michael Schnekenburger (LBMCC, Luxemburg):
Non-canonical cell death by sirtuin inhibitors
12:00 – 12:30: Keun-Tae Kim (Sogang University, South Korea)
Clinical implications of autophagy and ER stress in ovarian cancer
12:30 – 13:00: Han-Jung Chae (Department of Pharmacology and Institute of New drug Development, Medical School, Chonbuk National University, Jeonju, Korea)
ER stress and autophagy
13:00 – 14:00: Lunch break
Board meeting of the International Cell Death Society
Session 6: Novel mechanisms in cell death (Chair: Maria Entezari)
14:00 – 15:00: Lorenzo Galluzzi (Weill Cornell Medical College, USA and Université Paris Descartes, France): Danger, death and immunity in anticancer therapy
15:00 – 15:30: Shazib Pervaiz (National University of Singapore, Singapore, Singapore): Pro-oxidant milieu promotes phosphorylation-dependent stability of the oncoprotein c-myc
15:30 – 16:00: Sharad Kumar (Cancer and Cell Biology, Center for Cancer Biology, University of South Australia): Regulation of autophagy-dependent cell death in Drosophila
16:00 – 16:30: Coffee break
16:30 – 18:30: Poster presentation session
19:00 – 21:00: Gala dinner
Saturday June 2nd, 2018
Session 7: Innovative cell death pathways (Chair: Flavia Radogna)
9:00 – 9:30: Shigekazu Nagata (Biochemistry and Immunology, Osaka University, Japan): Exposure of phosphatidylserine, and phosphatidylserine-dependent efferocytosis
9:30 – 10:00: Luca Scorrano (Dept. of Biology, University of Padua, Italy): Targeting the Opa1-dependent cristae remodeling pathway to enhance cancer cell death and block cancer angiogenesis
10:00 – 10:30: Samuel G. Katz (Yale University School of Medicine, New Haven, USA)
BOK controls apoptosis by calcium transfer through ER-mitochondrial contact sites
10:30 – 11:00: Coffee break
Session 8: Compound-mediated regulation of alternative cell death (Chair: Claudia Cerella)
11:00 – 11:30: Young-Joon Surh (College of Pharmacy, Seoul National University, South Korea): Helicobacter pylori-induced phosphorylation of STAT3 promotes mitophagy in human gastric epithelial cells
11:30 – 12:00: Injae Shin (Department of Chemistry, Yonsei University, Seoul, South Korea): A synthetic ion transporter that disrupts autophagy and induces apoptosis
12:00 – 12:30: Young-Il Hahn (Tumor Microenvironment Research Center and Research Institute of Pharmaceutical Science, Seoul National University, Seoul 08826, South Korea)
Curcumin-induced apoptosis in H-Ras transformed human mammary epithelial cells: Cysteine 259 of STAT3 as a putative target
12:30 - 13:00: Marc Diederich (College of Pharmacy, Seoul National University, South Korea)
Natural compound regulators of alternative cell death pathways
13:00 – 14:00: Lunch break
14:00 – 19:00: City trip
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