Mónica Galocha

Education

• MSc in Biotechnology, IST-ULisboa, 2017

• BSc in Biology, FC-ULisboa, 2015

Research Activities

• Mechanisms of antifungal drug resistance in Candida glabrata

• Fungal genomics and evolution

• Systems biology tools for the study of transcriptional regulatory networks

Selected Publications

Galocha, M., Viana, R., Pais, P., Silva-Dias, A., Cavalheiro, M., Miranda, I.M., Van Ende, M., Souza, C.S., Costa, C., Branco, J., Soares, C.M., Van Dijck, P., Rodrigues, A.G., Teixeira, M.C., “Genomic evolution towards azole resistance in Candida glabrata clinical isolates unveils the importance of CgHxt4/6/7 in azole accumulation”, Communications Biology, 5: 1118, 2022.

Pais, P.*, Galocha, M.*, Takahashi-Nakaguchi, A., Chibana, H., Teixeira, M.C., “Multiple genome analysis of Candida glabrata clinical isolates renders new insights into genetic diversity and drug resistance determinants”, Microbial Cell, 9(11): 174-189, 2022.

Pais, P., Galocha, M., California, R., Viana, R., Ola, M., Okamoto, M., Chibana, H., Butler, G., Teixeira, M.C., “Characterization of the Candida glabrata transcription factor CgMar1: role in azole susceptibility”, Journal of Fungi, 8: 61, 2022.

Galocha, M., Costa, I.V., Teixeira, M.C., “Carrier-Mediated Drug Uptake in Fungal Pathogens”, Genes, 11: 1324, 2020.

Pais, P., California, R., Galocha, M., Viana, R., Ola, M., Cavalheiro, M., Takahashi-Nakaguchi, A., Chibana, H., Butler, G., Teixeira, M.C., “Candida glabrata transcription factor Rpn4 mediates fluconazole resistance through regulation of ergosterol biosynthesis and plasma membrane permeability”, Antimicrobial Agents and Chemotherapy, 64: e00554-20, 2020.

Monteiro, P.T., Oliveira, J., Pais, P., Antunes, M., Palma, M., Cavalheiro, M., Galocha, M., Godinho, C.P., Martins, L.C., Bourbon, N., Mota, M.N., Ribeiro, R.A., Viana, R., Sá-Correia, I., Teixeira, M.C., “YEASTRACT+: a portal for cross-species comparative genomics of transcription regulation in yeasts”, Nucleic Acids Research, 48:D642-D649, 2020.

Galocha, M., Pais, P., Cavalheiro, M., Pereira, D., Viana, R., Teixeira, M.C., “Divergent approaches to virulence in C. albicans and C. glabrata: two sides of the same coin”, International Journal of Molecular Sciences, 20(9). pii: E2345, 2019.

Pais, P., Galocha, M., Miranda, I.M., Rodrigues, A.G., Teixeira, M.C., “Draft genome sequences from three clinical isolates of the pathogenic yeast Candida glabrata”, Microbial Resource Announcements, 8(35). pii: e00278-19, 2019.

Pais, P., Galocha, M., Viana, R., Cavalheiro, M., Pereira, D., Teixeira, M.C., “Microevolution of the pathogenic yeasts Candida albicans and Candida glabrata during antifungal therapy and host infection”, Microbial Cell, 6(3): 142 – 159, 2019.

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