He has held faculty positions at the University of Michigan and Mount Sinai, where he served as the Director of Quality Assurance for Mount Sinai Heart. Dr. Vaishnava is recognized for his editorial contributions, including his role as editor of the 15th edition of Fuster and Hurst's The Heart and as an assistant editor for the Journal of the American College of Cardiology. He has also authored numerous book chapters, notably on perioperative care in Harrison's Principles of Internal Medicine.

The first edition of the book, titled The Heart, was written in 1966 by John Willis Hurst, who had served as the cardiologist of former U.S. President Lyndon B. Johnson. In 1986, the book was renamed Hurst's The Heart.[1] It is currently in its 15th edition published as Fuster and Hurst's The Heart in June 2022.


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Permanent replacement of the heart in patients with end-stage congestive heart failure has long been sought after as the most definitive solution to an ever-growing problem. While cardiac transplantation is an effective therapy for many patients with end-stage congestive heart failure, this potential has been limited by the donor organ shortage and other limitations of long-term survival inherent in cardiac transplantation. While research anddevelopment of the total artificial heart continues to be of considerable interest, present-day mechanical circulatory support most commonly involves the use of left ventricular assist devices as a bridge to transplantation. Pneumatic and electromechanical pumps are now commonly employed in modern transplant practices with excellent hemodynamic function. The TCI HeartMate left ventricular assist device is now approved by the Food and Drug Administration for clinical implantation, with excellent preliminary results. Advances in the area of temporary and extended mechanical circulatory support are crucial to the ultimate development of a totally implantable artificial heart.

Five years ago at the 2013 combine, Utah standout defensive lineman Star Lotulelei was diagnosed with a heart condition, but was later cleared to play in the NFL and got selected 14th overall in the first round by Carolina.

But the NFL Network reported that it was New Orleans Saints doctors who discovered Hurst's heart condition, and that it bore some similarity to the condition that prompted former Lions and Saints defensive tackle Nick Fairley to not be cleared to play in 2017. Fairley was released last month by New Orleans with a non-football illness designation.

Survivors include a sister, Jean Hurst McKay of Bay Village, Ohio; and three nieces. Gabriel Rettaliata, a former autoworker who sold cars for 30 years, died Wednesday of heart failure at his home in Yale Heights. He was 86.

OBJECTIVE: To assess the clinical and demographic characteristics of a population with ischemic heart disease admitted in the final decades of the 20th century. METHODS: This study retrospectively assessed patients hospitalized with ischemic heart disease divided into the following 2 groups: acute group - 11.181 patients with acute myocardial infarction admitted from 1/1/82 to 12/31/94; and chronic group - 4.166 patients undergoing coronary artery bypass graft surgery from 1/1/84 to 12/31/94. RESULTS: In the acute group, an increase in the percentage of females (from 22.7% to 27.7%, P

CONCLUSION: The characteristics of the population studied with ischemic heart disease point towards a worse prognosis, due to the greater percentages of females, older patients, and diabetic patients, groups known to have greater in-hospital mortality.

The objective of this study was to assess the clinical and demographic characteristics of the population with ischemic heart disease who were admitted to the Instituto do Corao (InCor) of the Medical School of the University of So Paulo in the final 2 decades of the 20th century.

The present study retrospectively analyzed patients diagnosed with ischemic heart disease admitted to InCor with the acute and chronic forms of ischemic heart disease. Two groups of patients were defined as follows: acuteĀ  comprising patients aged 20 years or older diagnosed with acute myocardial infarction and admitted to the hospital from 1/1/82 to 12/31/94. The criteria used for diagnosing myocardial infarction were the same as those used in the World Health Organization MONICA Project 16; chronicĀ  comprising patients diagnosed with ischemic heart disease and undergoing coronary artery bypass graft surgery. Only patients older than 20 years and admitted to the hospital from 1/1/84 to 12/31/94 were studied, and the diagnosis of ischemic heart disease met the classical clinical and cine coronary angiographic criteria of the national and international literature 17,18. In the latter group, the diagnosis of myocardial infarction was an exclusion criterion to prevent patients from being included in both groups.

This study revealed a significant increase in the age and number of females among the patients with the acute and chronic forms of ischemic heart disease. This study also corroborated the findings of previous studies, in which females were older than males 7,8,22 .

In regard to the chronic form of ischemic heart disease, Pepine et al 12 studied a population of 5.125 patients with chronic stable angina in 1990 and reported the predominance of females (53%) with an elevated mean age greater than that of males (70.8 vs 67.2 years). In comparison with previous studies, the authors concluded that the characteristics of the population with chronic stable angina have been changing, and that, independent of the causes involved, that information is important for understanding the natural history of the disease and for selecting the appropriate diagnostic and therapeutic strategies.

No study about the secular trends of the characteristics of the population undergoing myocardial revascularization has been found in the literature. Although Pepine et al 12 studied a different population and did not analyze other time periods, their study confirmed our findings in patients with the chronic form of ischemic heart disease undergoing that procedure.

Several studies have reported the occurrence of a reduction in the incidence of ischemic heart disease, and some authors have suggested that this reduction is smaller in the female sex 3,23. This fact could account for the findings in this and other studies regarding the increase in the percentage of females with ischemic heart disease. The tendency towards a smaller reduction in smoking in the female sex as compared with that in the male sex (observed in the last Brazilian census) and the growing participation of females in the job market could relate to these data.

In a larger population, our study showed a significant increase in the incidence of diabetes in association with myocardial infarction during the period from 1982 to 1994. Changes in the age profile could contribute to the greater frequency of that association, because diabetes is the most prevalent disease in the older segments of the population 12. This finding has important clinical implications, because the greater prevalence of diabetes as a comorbidity in ischemic heart disease is associated with a greater number of complications and a more prolonged hospitalization, which was observed in the acute group. In the latter group, the diagnosis of diabetes associated with myocardial infarction relates to higher in-hospital mortality rates.

In conclusion, all these findings point to a change in the profile of the population with ischemic heart disease admitted to InCor during the period studied, indicating a poorer prognosis associated with greater morbidity and mortality rates. This suggests that in the final decade of the 20th century, the patients became older, more females were affected, and the prevalence of diabetes mellitus increased.

Our study also confirms the findings of previous studies regarding the greater in-hospital mortality due to ischemic heart disease in females, in the elderly, and in patients with diabetes mellitus as an associated disease. Despite these results, no change in in-hospital mortality was observed during the study period. The recent advances in treatment and prevention of ischemic heart disease may have somehow compensated for the changes in the patients' characteristics. 17dc91bb1f

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