Yonghan Li,Siddabasave Gowda B. Gowda,Divyavani Gowda,Atsuko Ikeda,Yu Ait Bamai,Rahel Mesfin Ketema,Reiko Kishi,Hitoshi Chiba and Shu-Ping Hui (2025). Development of a Liquid Chromatography–Tandem Mass Spectrometry Method for Oxylipin Analysis and Its Application to Children’s Plasma, Diagnostics.
Amai, S., Yuki, K., Gowda, S. G. B., Gowda, D., & Hui, S. P. (2025). Lipidomic Profiling of Edible Japanese Sea Urchins by LC–MS. Foods, 14(13), 2268.
Dibwe, D. F., Oba, S., Monde, S., & Hui, S. P. (2025). Inhibition of Triacylglycerol Accumulation and Oxidized Hydroperoxides in Hepatocytes by Allium cepa (Bulb). Antioxidants, 14(6), 653.
Hsinjung Ho, Natsumi Aoki, Miki Eguchi, Mingchen Gao, Hirotaka Suzuki, Mao Mikami, Hitoshi Chiba, Shu-Ping Hui (2025).Vitamin K2 Attenuates Mitochondrial Damage in Renal Proximal Tubular Cells. Journal of Agricultural and Food Chemistry.
Jayaprakash, J., Gowda, D., M. Gangadhara, R., Jain, S., Yadav, H., B. Gowda, S. G., & Hui, S. P. (2025). Discovering Novel Short‐and Medium‐Chain Esters of Hydroxy Fatty Acids in Human Fecal Samples Using Untargeted Liquid Chromatography/Mass Spectrometry. Rapid Communications in Mass Spectrometry, 39(12), e10032.
Yifan Chen, Siddabasave Gowda B. Gowda, Divyavani Gowda, Jayashankar Jayaprakash, Lipsa Rani Nath, Atusko Ikeda, Yu Ait Bamai, Rahel Mesfin Ketema, Reiko Kishi, Hitoshi Chiba, Shu-Ping Hui (2025). Quantitative determination of plasmalogens by LC-MS/MS in preadolescent children-the Hokkaido study.diagnostics.
Qin, Wei; Hu, Feifei; Hui, Shu-Ping (2025). Comparative study of total polyphenol content and antioxidant activity of yomogi tea and green tea during simulated in vitro gastrointestinal digestion, ACS Food Science & Technology
Jayaprakash, Jayashankar, Gowda, Siddabasave Gowda B, Gowda, Divyavani, Ikeda, Atsuko, Bamai, Yu Ait, Ketema, Rahel Mesfin, Kishi, Reiko, Chen, Yifan, Chiba, Hitoshi, Hui, Shu-Ping (2025). Plasma Lipidomics of Preadolescent Children: A Hokkaido Study. Journal of Lipids, 2025(1), 3106145.
Dibwe, D. F., Oba, S., Monde, S., & Hui, S. P. (2024). Inhibition of Accumulation of Neutral Lipids and Their Hydroperoxide Species in Hepatocytes by Bioactive Allium sativum Extract. Antioxidants, 13(11), 1310.
Jayaprakash, J., Nath, L.R., B. Gowda, S.G. et al. Analysis and functions of bioactive lipids in food. Discov Food 4, 107 (2024). https://doi.org/10.1007/s44187-024-00186-5
Rachana M. Gangadhara, Siddabasave Gowda B. Gowda, Kota Yanagimoto, Divyavani Gowda, Hitoshi Chiba & Shu-Ping Hui. Lipidomics of herbal tea revealed their potential lipid nutrients including novel fatty acid esters of hydroxy fatty acids, (2024) J. Food Meas. Charact.
Gunjan Upadhyay, Siddabasave Gowda B. Gowda, Sidharth P. Mishra, Lipsa Rani Nath, Adewale James, Alisha Kulkarni, Yuktee Srikant, Rohitram Upendram, MathanKumar Marimuthu, Shu-Ping Hui, Shalini Jain, Kain Vasundhara, Hariom Yadav, Ganesh V. Halade. Targeted and untargeted lipidomics with integration of liver dynamics and microbiome after dietary reversal of obesogenic diet targeting inflammation-resolution signaling in aging mice, (2024), Biochim. Biophys. Acta, Mol. Cell Biol. Lipids.
Lipsa Rani Nath, Siddabasave Gowda B. Gowda*, Thomas H. Roberts, Divyavani Gowda, Ali Khoddami, Shu-Ping Hui*. Nontargeted Lipidomics of Sorghum Grain Reveals Novel Fatty Acid Esters of Hydroxy Fatty Acids and Cultivar Differences in Lipid Profiles. (2024), J. Agric. Food Chem.
Nao Inoue, Siddabasave Gowda B. Gowda, Divyavani Gowda, Toshihiro Sakurai, Atsuko Ikeda-Araki1, Yu Ait Bamai, Rahel Mesfin Ketema, Reiko Kishi, Hitoshi Chiba, and Shu-Ping Hui, Determination of plasma lysophosphatidylethanolamines (lyso-PE) by LC-MS/MS revealed a possible relation between obesity and lyso-PE in Japanese preadolescent children: the Hokkaido study. (2024), Annals of Clinical Biochemistry.
Gowda Divyavani, Gowda Siddabasave Gowda B., Ikeda Atsuko, Mesfin Ketema Rahel, Ait Bamai Yu, Kishi Reiko, Chiba Hitoshi, Hui Shu-Ping, Quantitative determination of plasma cholesteryl ester levels in Japanese preadolescents from the Hokkaido study using liquid chromatography/tandem mass spectrometry. (2024), Steroids, 109498.
Gowda Divyavani, Masum Md. Abdul, B. Gowda Siddabasave Gowda, Shekhar Chandra, Rubel Md. Zahir Uddin, Kira Shunnosuke, Ichii Osamu, Kon Yasuhiro, Chiba Hitoshi, Hui Shu-Ping, Lipidomic study of kidney in a mouse model with urine flow obstruction. (2024), Scientific Reports, 14, 18042.
Koshi Nakamura, Seiji Takeda, Toshihiro Sakurai, Shigekazu Ukawa, Emiko Okada, Takafumi Nakagawa, Akihiro Imae, Shu-Ping Hui, Hitoshi Chiba, Akiko Tamakoshi. (2024). Relationships of the Surface Charge of Low-Density Lipoprotein (LDL) with the Serum LDL-Cholesterol and Atherosclerosis Levels in a Japanese Population: The DOSANCO Health Study. Journal of Atherosclerosis and Thrombosis, 64961.
Raju, P., Shukla, P., Gowda, S. G. B., Basa, L., Shekhar, C., Nguyen, C., Shashikanth, N. (2024). Paneth Cell-Specific TRPV6 Channel Plays a Crucial Role in Alcohol-Associated Dysbiosis of Gut Microbiota and Tissue Injury at the Gut-Liver Axis. Physiology, 39(S1), 2555.
Malek, M. A., B Gowda, S. G., M Gangadhara, R., Gowda, D., & Hui, S. P. (2024). Exploration of New Lipid Nutrients and Their Characterization in Herbal Teas Using Non-Targeted Liquid Chromatography–Mass Spectrometry. Foods, 13(12), 1877.
Yonghan Li, Siddabasave Gowda B. Gowda, Divyavani Gowda, Atsuko Ikeda, Yu Ait Bamai, Rahel Mesfin Ketema, Reiko Kishi, Hitoshi Chiba, Shu-Ping Hui, (2024), Alterations in plasma short-chain fatty acids in preadolescence children: The Hokkaido study, Journal of Chromatography B.
N Murakami, T Sakurai, A Yamahata, A Sakurai, K Nouso, Y Fujii, H Chiba, SP Hui (2024). Increased phosphatidylcholine and its hydroperoxides in serum low-density lipoproteins from patients with non-alcoholic steatohepatitis. Annals of Clinical Biochemistry, 00045632241259658.
Sundaraswamy, P. M.#, Minami, Y.#, Jayaprakash, J.#, Gowda, S. G. B., Takatsu, H., Gowda, D., Shin, H. W., & Hui, S. P. (2024). A facile method for monitoring sphingomyelin synthase activity in HeLa cells using liquid chromatography/mass spectrometry. Analyst.
Gowda, S. G. B.#, Nath, L. R.#, Li, Y., Jayaprakash, J., Gowda, D., & Hui, S. P. Sex-specific effect of ethanol on colonic short-chain fatty acids and derivatives in the mouse model using targeted LC/MS.
Dya Fita Dibwe, Emi Kitayama, Saki Oba, Nire Takeishi, Hitoshi Chiba, Shu-Ping Hui * (2024). Inhibition of Lipid Accumulation and Oxidation in Hepato-cytes by Bioactive Bean Extracts. Antioxidants.
Jayashankar Jayaprakash, Siddabasave Gowda B. Gowda*, Pradeep K. Shukla, Divyavani Gowda, Lipsa Rani Nath, Hitoshi Chiba, Radhakrishna Rao, and Shu-Ping Hui* (2024). Sex-Specific Effect of Ethanol on Colon Content Lipidome in a Mice Model Using Nontargeted LC/MS. ACS Omega.
Minami, Y., Gowda, S. G. B., Gowda, D., Chiba, H., & Hui, S. P. (2024). Regio-specific lipid fingerprinting of edible sea cucumbers using LC/MS. Food Research International, 114253.
Nath, L. R., Gowda, S. G. B., Gowda, D., Hou, F., Chiba, H., & Hui, S. P. (2024). Dissecting new lipids and their composition in herbal tea using untargeted LC/MS. Food Chemistry, 138941.
Akiko Sakurai, Toshihiro Sakurai *, Hsin-Jung Ho, Hitoshi Chiba, Shu-Ping Hui *. Kaempferol is a potential nutrition factor that prevents metabolic dysfunction-associated steatotic liver disease through improving mitochondrial cardiolipin profile and ATP synthesis, Nutrients (accepted 2024).
Natsuki Kita, Asuka Hamamoto, Siddabasave Gowda B Gowda, Hiroyuki Takatsu, Kazuhisa Nakayama, Makoto Arita, Shu-Ping Hui, Hye-Won Shin, Glucosylceramide flippases contribute to cellular glucosylceramide homeostasis, Journal of Lipid Research, 100508. doi: 10.1016/j.jlr.2024.100508.
Malek Md Abdul, B. Gowda Siddabasave Gowda, Gowda Divyavani, Hui Shu-Ping. Analysis of lipid composition and characterization of acyl steryl glycosides in rose petals by using nontargeted LC/MS. Journal of Food Measurement and Characterization, doi: 10.1007/s11694-023-02329-1.
Asuka Hamamoto, Natsuki Kita, Siddabasave Gowda B Gowda, Hiroyuki Takatsu, Kazuhisa Nakayama, Makoto Arita, Shu-Ping Hui, Hye-Won Shin. Lysosomal membrane integrity in fibroblasts derived from patients with Gaucher disease. Cell Structure and Function, 2024, 49.1: 1-10. doi: 10.1247/csf.23066.
Siddabasave Gowda B. Gowda¹, Fengjue Hou¹, Divyavani Gowda, Hitoshi Chiba, Kentaro Kawakami, Satoru Fukiya, Atsushi Yokota, Shu-Ping Hui. Synthesis and quantification of short-chain fatty acid esters of hydroxy fatty acids in rat intestinal contents and fecal samples by LC-MS/MS, Analytica Chimica Acta, 2023. https://doi.org/10.1016/j.aca.2023.342145
Dya Fita Dibwe, Nire Takeishi, Saki Oba, Akiko Sakurai, Toshihiro Sakurai, Takayuki Tsukui, Hitoshi Chiba, Shu-Ping Hui*. Identification of a β-carboline alkaloid that prevents lipid droplet accumulation in human hepatocytes (HepG2) by targeted NMR and LC/MS finger printing of chemo-selective derivatives from vanilla bean extract. Molecules, 2023 (accepted).
B Gowda, S. G., Gowda, D., Hou, F., Shekhar, C., Chiba, H., Patzke, N., & Hui, S. P. Regiospecific Analysis of Lipidome in Brain from Animals of Land and Aquatic Habitats-By Liquid Chromatography-Mass Spectrometry. Heliyon, 2023 (accepted).
Xun-Zhi Wu¹, Hsin-Jung Ho¹, Miki Eguchi, Zhen Chen, Hitoshi Chiba, Shu-Ping Hui*. Flazin improves mitochondrial dynamics in renal tubular epithelial cells under oxidative stress. Food Bioscience, 2023 (accepted)
Divyavani Gowda, Chandra Shekar, Siddabasave Gowda B. Gowda*, Chen Yifan, Shu-Ping Hui*. Crosstalk between lipids and non-alcoholic fatty liver disease. Livers. 2023 (accepted)
Marumi Ohno, Siddabasave Gowda B. Gowda, Toshiki Sekiya, Naoki Nomura, Masashi Shingai, Shu-Ping Hui, Hiroshi Kida. The elucidation of plasma lipidome profiles during severe influenza in a mouse model. Sci Rep 13, 14210 (2023). https://doi.org/10.1038/s41598-023-41055-y
Yue Wu, Yifan Chen, Min Zhang, Hitoshi Chiba, Shu-Ping Hui. Plasmalogen profiling in porcine brain tissues by LC-MS/MS. Foods. 2023 (accepted)
Rachana M Gangadhara, Siddabasave Gowda B. Gowda, Divyavani Gowda, Ken Inui, Shu-Ping Hui. Lipid composition analysis and characterization of acyl sterol glycosides in Adzuki and Soybean cultivars by non-targeted LC-MS. Foods. 2023 (accepted)
Hsin-Jung Ho, Natsumi Aoki, Yi-Jou Wu, Ming-Chen Gao, Karin Sekine, Toshihiro Sakurai, Hitoshi Chiba, Hideaki Watanabe, Mitsugu Watanabe, Shu-Ping Hui. A Pacific oyster-derived antioxidant, DHMBA, protected renal tubular HK-2 cells against oxidative stress via reduction of mitochondrial ROS production and fragmentation. Int J Mol Sci. 2023 (accepted)
Siddabasave Gowda B Gowda, Chandra Shekhar, Divyavani Gowda, Yifan Chen, Hitoshi Chiba, and Shu-Ping Hui. Mass spectrometric approaches in discovering lipid biomarkers for COVID-19 by lipidomics: future challenges and perspectives. Mass Spectrom Rev. 2023 Apr 27. doi: 10.1002/mas.21848.
Halade GV, Mat Y, Gowda SGB, Jain S, Hui SP, Yadav H, Kain V. Sleep deprivation in obesogenic setting alters lipidome and microbiome toward suboptimal inflammation in acute heart failure. FASEB J. 2023 May;37(5):e22899. doi: 10.1096/fj.202300184R.
Zhen Chen, Shuji Sai, Kiyoshi Nagumo, Yue Wu, Hitoshi Chiba, Shu-Ping Hui. Distinctive serum lipidomic profile of IVIG-resistant Kawasaki disease children before and after treatment. PLOS ONE. 2023 (accepted)
Iku Sazaki#, Toshihiro Sakurai#, Arisa Yamahata, Sumire Mogi, Nao Inoue, Koutaro Ishida, Ami Kikkai, Hana Takeshita, Akiko Sakurai, Yuji Takahashi, Hitoshi Chiba, and Shu-Ping Hui. Oxidized low-density lipoproteins trigger hepatocellular oxidative stress with formation of cholesteryl ester hydroperoxide-enriched lipid droplets. Int J Mol Sci. 2023 (accepted)
Zhen Chen† , Nianqiu Shen† , Xunzhi Wu, Jiaping Jia, Yue Wu, Hitoshi Chiba, and Shuping Hui. Extraction and quantitation of phytosterols from edible brown seaweeds: optimization, validation, and application. Foods. 2023, 12, 244. doi: 10.3390/foods12020244
Siddabasave Gowda B. Gowda, Divyavani Gowda, Fengjue Hou, Hitoshi Chiba, Vibhu Parcha, Pankaj Arora, Ganesh V. Halade, Shu-Ping Hui* . Temporal Lipid Profiling in the Progression from Acute to Chronic Heart Failure in Mice and Ischemic Human Hearts. Atherosclerosis. 2022 (accepted)
Zhen Chen, Rojeet Shrestha, Xiaoyue Yang, Xunzhi Wu, Jiaping Jia, Hitoshi Chiba, Shu-Ping Hui * . Oxidative stress and lipid dysregulation in lipid droplets: a connection to chronic kidney disease revealed in human renal proximal tubular cells. Antioxidants. 2022 (accepted)
Divyavani Gowda , Yonghan Li, Siddabasave Gowda B. Gowda , Marumi Ohno ,Hitoshi Chiba , and Shu-Ping Hui. Determination of short-chain fatty acids by N, N-dimethylethylenediamine derivatization combined with liquid-chromatography/mass spectrometry and their implication in influenza virus infection.Analytical and Bioanalytical Chemistry. 2022 (accepted)
Qiao, L.; Chen, Z.; Takada, C.; Chiba, H.; Inoue, K.; Hui, S.-P.; Ye, S. Quantitative Evaluation on the Degradation Process of the Pulmonary Surfactant Monolayer When Exposed to Low-Level Ozone of Ambient Environment. Anal. Chem. 2022, doi:10.1021/acs.analchem.2c00576
Gowda, S. G. B.#, Minami, Y.#, Gowda, D., Chiba, H., & Hui, S. P. Detection and characterization of lipids in eleven species of fish by non-targeted liquid chromatography/mass spectrometry. Food Chemistry, 2022, 393, 133402.
Inoue N, Sakurai T, Yamamoto Y, Chiba H, Hui SP. Profiling of lysophosphatidylethanolamine molecular species in human serum and in silico prediction of the binding site on albumin. BioFactors, 2022 (in press)
Dya Fita Dibwe, Saki Oba, Nire Takeishi, Toshihiro Sakurai, Takayuki Tsukui, Hitoshi Chiba, Shu-Ping Hui. Food-Derived β-Carboline Alkaloids Ameliorate Lipid Droplet Accumulation in Human Hepatocytes. Pharmaceuticals 2022, 15(5), 578. doi: 10.3390/ph15050578
Xunzhi Wu, Zhen Chen, Yue Wu, Yifan Chen, Jiaping Jia, Nianqiu Shen, Hitoshi Chiba, Shu-Ping Hui. Flazin as a lipid droplet regulator against lipid disorders. Nutrients 2022, 14(7), 1501. doi: 10.3390/nu14071501
Zhen Chen, Jiaping Jia, Yue Wu, Hitoshi Chiba, Shu-Ping Hui. LC/MS Analysis of Storage-Induced Plasmalogen Loss in Ready-to-Eat Fish. Food Chem 2022, 383,132320. doi:10.1016/j.foodchem.2022.132320
Yusuke Yamamoto, Toshihiro Sakurai, Zhen Chen, Nao Inoue, Hitoshi Chiba, Shu-Ping Hui. Lysophosphatidylethanolamine affects lipid accumulation and metabolism in a human liver-derived cell line. Nutrients 2022, 14(3), 579. doi: 10.3390/nu14030579
Chongsheng Liang, Siddabasave Gowda B. Gowda, Divyavani Gowda, Toshihiro Sakurai, Iku Sazaki, Hitoshi Chiba, and Shu-Ping Hui. Simple and sensitive method for the quantitative determination of lipid hydroperoxides by liquid chromatography/mass spectrometry. Antioxidants 2022, 11(2), 229. doi: 10.3390/antiox11020229
Zijian Zhu, Zhen Chen, Toshihiro Sakurai, Hitoshi Chiba, and Shu-Ping Hui. Adverse Effects of Chrysene on Human Hepatocytes via Inducement of Oxidative Stress and Dysregulation of Xenobiotic Metabolism. Polycyclic Aromatic Compounds (Accepted)
Yue Wu, Zhen Chen, Hirotoshi Fuda, Takayuki Tsukui, Xunzhi Wu, Nianqiu Shen, Natsuki Saito, Hitoshi Chiba, Shu-Ping Hui. Oxidative Stress Linked Organ Lipid Hydroperoxidation and Dysregulation in Mouse Model of Nonalcoholic Steatohepatitis: Revealed by Lipidomic Profiling of Liver and Kidney. Antioxidants (Accepted)
Eri Furukawa, Zhen Chen, Hiroki Ueshiba, Yue Wu, Hitoshi Chiba, Yojiro Yanagawa, Seiji Katagiri, Masashi Nagano, Shu-Ping Hui. Postpartum cows showed high oocyte triacylglycerols concurrently with high plasma free fatty acids. Theriogenology. (Accepted)
Divyavani Gowda, Marumi Ohno, Siddabasave Gowda B. Gowda, Hitoshi Chiba, Masashi Shingai, Hiroshi Kida, and Shu-Ping Hui: Defining the kinetic effects of infection with influenza virus A/PR8/34 (H1N1) on sphingosine-1-phosphate signaling in mice by targeted LC/MS. Scientific Reports. (Accepted)
Zi-Jun Gao, Zhen Chen, Shu-Ping Hui. Effect of charcoal grilling on polycyclic aromatic hydrocarbons (PAHs): content, composition, and health risk in edible fish in Japan. Analytical Sciences. (Accepted)
Yifan Chen, Yusuke Miura, Toshihiro Sakurai, Zhen Chen, Rojeet Shrestha, Sota Kato, Emiko Okada, Shigekazu Ukawa, Takafumi Nakagawa, Koshi Nakamura, Akiko Tamakoshi, Hitoshi Chiba, Hideyuki Imai, Hiroyuki Minami, Masahiro Mizuta, and Shu-Ping Hui. Comparison of four statistical analytical methods on dietary sources of human serum fatty acids. Scientific Reports (Accepted)
Siddabasave Gowda B. Gowda, Divyavani Gowda, Vasundhara Kain, Hitoshi Chiba, Shu-Ping Hui*, Charles E. Chalfant, Vibhu Parcha, Pankaj Arora, Ganesh Halade*. Sphingosine-1-phosphate interactions in the spleen and heart reflect extent of cardiac repair in mice and failing human hearts. Am. J. Physiol. Heart Circ. Physiol. (Accepted)
Siddabasave Gowda B. Gowda, Takayuki Tsukui, Hirotoshi Fuda, Yusuke Minami, Divyavani Gowda, Hitoshi Chiba, Shu-Ping Hui. Docosahexaenoic Acid Esters of Hydroxy Fatty Acid is a Novel Activator of NRF2. International Journal of Molecular Sciences (Accepted)
B. Gowda, Siddabasave Gowda; Gowda, Divyavani; Ohno, Marumi; Liang, Chongsheng; Chiba, Hitoshi; Hui, Shu-Ping. Detection and Structural Characterization of SFAHFA Homologous Series in Mouse Colon Contents by LTQ-Orbitrap-MS and Their Implication in Influenza Virus Infection. Journal of the American Society for Mass Spectrometry (Accepted)
Gowda, SGB, Liang, C, Gowda, D, et al. Identification of short-chain fatty acid esters of hydroxy fatty acids (SFAHFAs) in a murine model by nontargeted analysis using ultra-high-performance liquid chromatography/linear ion trap quadrupole-Orbitrap mass spectrometry. Rapid Commun Mass Spectrom. 2020; 34:e8831. https://doi.org/10.1002/rcm.8831
Moto Fukai; Takuya Nakayabu; Shintaro Ohtani; Kengo Shibata; Shingo Shimada; Soudai Sakamoto; Hirotoshi Fuda; Takayuki Furukawa; Mitsugu Watanabe; Shu-Ping Hui; Hitoshi Chiba; Tsuyoshi Shimamura; Akinobu Taketomi. The phenolic antioxidant 3,5-dihydroxy-4-methoxybenzyl alcohol (DHMBA) prevents enterocyte cell death under oxygen-dissolving cold conditions through polyphyletic antioxidant actions. J. Clin. Med. (Accepted)
Siddabasave Gowda B. Gowda, Yuka Sasaki, Eisuke Hasegawa, Hitoshi Chiba and Shu-Ping Hui. Lipid fingerprinting of yellow mealworm Tenebrio molitor by untargeted liquid chromatography-mass spectrometry. Journal of Insects as Food and Feed (Accepted)
Siddabasave Gowda B. Gowda, Yusuke Minami, Divyavani Gowda, Daisuke Furuko, Hitoshi Chiba, Shu-Ping Hui. Lipidomic analysis of non-esterified furan fatty acids and fatty acid compositions in dietary shellfish and salmon by UHPLC/LTQ-Orbitrap-MS, Food Research International, 2021 (Accepted) doi: 10.1016/j.foodres.2021.110325
Shrestha, R.; Chen, Z.; Gao, Z.; Chen, Y.; Okada, E.; Ukawa, S.; Nakagawa, T.; Nakamura, K.; Tamakoshi, A.; Chiba, H.; & Hui, S.-P. HPLC with Spectrophotometric or Mass Spectrometric detection for quantifying Very-Long Chain Fatty Acids in Human Plasma and its Association with Cardiac Risk Factors. Annals of Clinical Biochemistry. 2021;000456322110071. doi:10.1177/00045632211007157
Sakurai, T.; Chen, Z.; Yamahata, A.; Hayasaka T.; Satoh, H.; Sekiguchi, H.; Chiba, H.; Hui, S.-P. A mouse model of short-term, diet-induced fatty liver with abnormal cardiolipin remodeling via downregulated Tafazzin gene expression. J Sci Food Agri. https://doi.org/10.1002/jsfa.11144 (Accepted)
Wu Y, Chen Z, Jia J, Chiba H, Hui S-P. Quantitative and Comparative Investigation of Plasmalogen Species in Daily Foodstuffs. Foods 2021;10:124. doi:10.3390/foods10010124.
Yamamoto, Y.; Sakurai, T.; Chen, Z.; Furukawa, T.; Gowda, S. G. B.; Wu, Y.; Nouso, K.; Fujii, Y.; Yoshikawa, Y.; Chiba, H.; et al. Analysis of Serum Lysophosphatidylethanolamine Levels in Patients with Non-Alcoholic Fatty Liver Disease by Liquid Chromatography-Tandem Mass Spectrometry. Anal Bioanal Chem 2021, 413:245–54. doi:10.1007/s00216-020-02996-9.
Chen Z, Liang Q, Wu Y, Gao Z, Kobayashi S, Patel J, Li C, Cai F, Zhang Y, Liang C, Chiba H, Hui S-P. Comprehensive lipidomic profiling in serum and multiple tissues from a mouse model of diabetes. Metabolomics 2020, 16:115.
B. Gowda, S.G.; Gowda, D.; Liang, C.; Li, Y.; Kawakami, K.; Fukiya, S.; Yokota, A.; Chiba, H.; Hui, S.-P. Chemical Labeling Assisted Detection and Identification of Short Chain Fatty Acid Esters of Hydroxy Fatty Acid in Rat Colon and Cecum Contents. Metabolites 2020, 10, 398.
Fujii, Y.; Nouso, K.; Matsushita, H.; Kariyama, K.; Sakurai, T.; Takahashi, Y.; Chiba, H.; Hui, S.-P.; Ito, Y.; Ohta, M.; et al. Low-Density Lipoprotein (LDL)-Triglyceride and Its Ratio to LDL-Cholesterol as Diagnostic Biomarkers for Nonalcoholic Steatohepatitis. J. Appl. Lab. Med. 2020, March, 1–10.
Siddabasave Gowda B. Gowda, Hirotoshi Fuda, Takayuki Tsukui, Hitoshi Chiba, Shu-Ping Hui. Discovery of Eicosapentaenoic Acid Esters of Hydroxy Fatty Acids as Potent Antioxidants via Activation of Keap1-Nrf2 Signaling. Antioxidants 2020, 9 (5), 397. doi: 10.3390/antiox9050397
Wu Y, Chen Z, Chiba H, Hui S-P. Plasmalogen fingerprint alteration and content reduction in beef during boiling, roasting, and frying. Food Chem 2020;322:126764. doi:10.1016/j.foodchem.2020.126764.
Gowda, S. G. B.; Gao, Z.-J.; Chen, Z.; Abe, T.; Hori, S.; Fukiya, S.; Ishizuka, S.; Yokota, A.; Chiba, H.; Hui, S.-P. Untargeted Lipidomic Analysis of Plasma from High Fat Diet-Induced Obese Rats Using UHPLC- Linear Trap Quadrupole -Orbitrap MS. Anal. Sci. 2020.
Chen, Z.; Wu, Y.; Nagano, M.; Ueshiba, K.; Furukawa, E.; Yamamoto, Y.; Chiba, H.; Hui, S.-P. Lipidomic Profiling of Dairy Cattle Oocytes by High Performance Liquid Chromatography-High Resolution Tandem Mass Spectrometry for Developmental Competence Markers. Theriogenology 2020, 144, 56–66.
Chen, Y.; Hui, S. P.; Miura, Y.; Kato, S.; Sakurai, T.; Chen, Z.; Okada, E.; Ukawa, S.; Nakagawa, T.; Nakamura, K.; et al. Multivariate Analysis for Molecular Species of Cholesteryl Ester in the Human Serum. Anal. Sci. 2019.
H. Fuda, S. Miyanaga, T. Furukawa, S. Umetsu, S. Joko, Y. Roan, H. Suzuki, S.-P. Hui, M. Watanabe, H. Chiba, Flazin as a promising Nrf2 pathway activator, J. Agric. Food Chem. (2019) acs.jafc.9b04600. doi:10.1021/acs.jafc.9b04600.
Ayabe, H. Kumahara, A. Yamaguchi-Watanabe, H. Chiba, N. Kobayashi, I. Sakuma, K. Ishii, Appendicular muscle mass and exercise/sports participation history in young Japanese women, Ann. Hum. Biol. 46 (2019) 335–339. doi:10.1080/03014460.2019.1641221.
Nishimura, Kenji; Murakami, Taichi; Sakurai, Toshihiro; Miyoshi, Masashi; Kurahashi, Kiyoe; Kishi, Seiji; Tamaki, Masanori; Tominaga, Tatsuya; Yoshida, Sumiko; Nagai, Kojiro; Hui, Shu-Ping; Kotani, Kazuhiko; Doi, Toshio. (2019). Circulating Apolipoprotein L1 is associated with insulin resistance-induced abnormal lipid metabolism. Scientific Reports. 9. 10.1038/s41598-019-51367-7.
Miki, K.; Kitada, S.; Miki, M.; Hui, S.-P.; Shrestha, R.; Yoshimura, K.; Tsujino, K.; Kagawa, H.; Oshitani, Y.; Kida, H.; et al. (2019) A Phase II, Open-Label Clinical Trial on the Combination Therapy with Medium-Chain Triglycerides and Ghrelin in Patients with Chronic Obstructive Pulmonary Disease. J. Physiol. Sci. (Accepted))
Kenji Nishimura, Taichi Murakami, Toshihiro SAKURAI, Masashi Miyoshi, Kiyoe Kurahashi, Seiji Kishi, Masanori Tamaki, Tatsuya Tominaga, Sumiko Yoshida, Kojiro Nagai, Hideharu Abe, Shu-Ping Hui, Kazuhiko Kotani, and Toshio Doi. (2019) Circulating Apolipoprotein L1 is associated with insulin resistance-induced abnormal lipid metabolism. Scientific Reports (In press).
Shrestha, R.; Chen, Z.; Miura, Y.; Yamamoto, Y.; Sakurai, T.; Chiba, H.; Hui, S.-P. (2019) Identification of Molecular Species of Phosphatidylcholine Hydroperoxides in Human Native and Copper-Oxidized Triglyceride-Rich Lipoproteins. Ann. Clin. Biochem. 000456321988093. (Accepted)
Chen, Z.; Gao, Z.; Wu, Y.; Shrestha, R.; Imai, H.; Uemura, N.; Hirano, K.; Chiba, H.; Hui, S.-P. (2019) Development of a Simultaneous Quantitation for Short-, Medium-, Long-, and Very Long-Chain Fatty Acids in Human Plasma by 2-Nitrophenylhydrazine-Derivatization and Liquid Chromatography–Tandem Mass Spectrometry. J. Chromatogr. B, 1126-1127, 121771.
Ikuta A, Sakurai T, Nishimukai M, Takahashi Y, Nagasaka A, Hui SP, Hara H, Chiba H (2019) Composition of plasmalogens in serum lipoproteins from patients with non-alcoholic steatohepatitis and their susceptibility to oxidation. Clin Chim Acta 493:1–7 . https://doi.org/10.1016/j.cca.2019.02.020
Nagai K, Uranbileg B, Chen Z, Fujioka A, Yamazaki T, Matsumoto Y, Tsukamoto H, Ikeda H, Yatomi Y, Chiba H, Hui S, Nakazawa T, Saito R, Koshiba S, Aoki J, Saigusa D, Tomioka Y (2019) Identification of novel biomarkers of hepatocellular carcinoma by high‐definition mass spectrometry: Ultrahigh‐performance liquid chromatography quadrupole time‐of‐flight mass spectrometry and desorption electrospray ionization mass spectrometry imaging. Rapid Commun Mass Spectrom rcm.8551 . https://doi.org/10.1002/rcm.8551
Yamamoto Y, Furukawa T, Takeda S, Kashida H, Chiba H, Hui S-P (2018) Examining the effect of regioisomerism on the physico-chemical properties of lysophosphatidylethanolamine-containing liposomes using fluoro probes. Chem Phys Lipids 216:9–16. doi: 10.1016/j.chemphyslip.2018.08.001
Shrestha R, Miura Y, Hirano K-I, Chen Z, Okabe H, Chiba H, Hui S-P (2018) Microwave-assisted Derivatization of Fatty Acids for Its Measurement in Milk Using High-Performance Liquid Chromatography. Anal Sci 34:575–582. doi: 10.2116/analsci.17P557
Chen Z, Zang L, Wu Y, Nakayama H, Shimada Y, Shrestha R, Zhao Y, Miura Y, Chiba H, Hui S-P, Nishimura N (2018) Lipidomic Profiling on Oxidized Phospholipids in Type 2 Diabetes Mellitus Model Zebrafish. Anal Sci. doi: 10.2116/analsci.18P281
Chen Z, Wu Y, Shrestha R, Gao Z, Zhao Y, Miura Y, Tamakoshi A, Chiba H, Hui S-P (2018) ANNALS EXPRESS: Determination of Total, Free, and Esterified Short-Chain Fatty Acid in Human Serum by LC-MS/MS. Ann Clin Biochem 4563218801393. doi: 10.1177/0004563218801393
Okabe H, Shimizu C, Yamamoto M, Kikuchi R, Minami A, Chen Y-F, Imai H, Mizuta M, Chen Z, Chiba H, Hui S-P (2018) Determination of Serum 25-Hydroxyvitamin D3 by LC/MS/MS and Its Monthly Variation in Sapporo Indoor Workers. Anal Sci 34:1043–1047. doi: 10.2116/analsci.18P193
Sakurai T, Sakurai A, Vaisman BL, Nishida T, Neufeld EB, Demosky SJ, Sampson ML, Shamburek RD, Freeman LA, Remaley AT (2018) Development of a novel fluorescent activity assay for lecithin:cholesterol acyltransferase. Ann Clin Biochem Int J Lab Med 55:414–421. doi: 10.1177/0004563217733285
Takahashi Y, Ito Y, Sakurai T, Wada N, Nagasaka A, Fujikawa M, Chiba H, Hui S-P (2018) A two-step homogeneous assay for apolipoprotein E-containing high-density lipoprotein-cholesterol. Ann Clin Biochem Int J Lab Med 000456321879521. doi: 10.1177/0004563218795212
Takeda S, Sakurai T, Hui SP, Fuda H, Chiba H (2018) Effects of enzymes on elastic modulus of low-density lipoproteins were investigated using atomic force microscopy. Biochem Biophys Res Commun 501:607–611. doi: 10.1016/j.bbrc.2018.04.211
Sakurai T, Hayasaka T, Sekiguchi H, Satoh H, Chen Z, Chiba H, Hui S-P (2018) Dietary salmon milt extracts attenuate hepatosteatosis and liver dysfunction in diet-induced fatty liver model. J Sci Food Agric. doi: 10.1002/jsfa.9352
Shrestha R, Hirano K-I, Suzuki A, Yamaguchi S, Miura Y, Chen Y-F, Mizuta M, Chiba H, Hui S-P (2017) Change in Plasma Total, Esterified and Non-esterified Capric Acid Concentrations during a Short-term Oral Administration of Synthetic Tricaprin in Dogs. Anal Sci 33:1297–1303. doi: 10.2116/analsci.33.1297
Zhao Y, Zhao H, Zhao X, Jia J, Ma Q, Zhang S, Zhang X, Chiba H, Hui S-P, Ma X (2017) Identification and Quantitation of C=C Location Isomers of Unsaturated Fatty Acids by Epoxidation Reaction and Tandem Mass Spectrometry. Anal Chem 89:10270–10278. doi: 10.1021/acs.analchem.7b01870
Furukawa T, Hinou H, Takeda S, Chiba H, Nishimura S-I, Hui S-P (2017) An Efficient Glycoblotting-Based Analysis of Oxidized Lipids in Liposomes and a Lipoprotein. ChemBioChem 18:1903–1909. doi: 10.1002/cbic.201700384
Chen Z, Wu Y, Ma Y-S, Kobayashi Y, Zhao Y-Y, Miura Y, Chiba H, Hui S-P (2017) Profiling of cardiolipins and their hydroperoxides in HepG2 cells by LC/MS. Anal Bioanal Chem 409:5735–5745. doi: 10.1007/s00216-017-0515-3
Joko S, Watanabe M, Fuda H, Takeda S, Furukawa T, Hui S-P, Shrestha R, Chiba H (2017) Comparison of chemical structures and cytoprotection abilities between direct and indirect antioxidants. J Funct Foods 35:245–255. doi: 10.1016/j.jff.2017.05.039
Miura Y, Furukawa T, Kobayashi M, Shrestha R, Takahashi R, Shimizu C, Chiba H, Hui SP. Absolute quantification of cholesteryl esters using liquid chromatography-tandem mass spectrometry uncovers novel diagnostic potential of urinary sediment. Steroids. 123:43-49, 2017
Matsushita S, Masaki N, Sato K, Hayasaka T, Sugiyama E, Hui SP, Chiba H, Mase N, Setou M. Selective improvement of peptides imaging on tissue by supercritical fluid wash of lipids for matrix-assisted laser desorption/ionization mass spectrometry. Anal Bioanal Chem. 409:1475-80,2017.
Ma YS, Yoshida S, Kobayashi Y, Kawanishi N, Furukawa T, Fuda H, Hui SP*, Chiba H. Improvement of Mitochondrial Function and Lipid Utilization by 3,5-dihydroxy-4-methoxybenzyl Alcohol, an Oyster-derived polyphenol, in Oleate-loaded C2C12 Myotubes. Journal of Food and Nutrition Research. 4:498-507, 2016
Hayasaka T, Fuda H, Hui SP, Chiba H. Imaging Mass Spectrometry Reveals a Decrease of Cardiolipin in the Kidney of NASH Model Mice. Anal Sci. 32:473-6, 2016
Yagi A, Miyanaga S, Shrestha R, Takeda S, Kobayashi S, Chiba H, Kamiya H, Hui SP. A fatty acid profiling method using liquid chromatography-high resolution mass spectrometry for improvement of assisted reproductive technology. Clin Chim Acta. 456:100-6, 2016
Miura Y, Hui SP, Shrestha R, Hiruma T, Takeda S, Fuda H, Ikegawa S, Hirano K, Chiba H. Synthesis of (2β,3α,6-²H₃cholesteryl linoleate and cholesteryl oleate as internal standards for mass spectrometry. Steroids. 107:1-9, 2016
Takahashi Y, Ito Y, Wada N, Nagasaka A, Fujikawa M, Sakurai T, Shrestha R, Hui SP, Chiba H. Development of homogeneous assay for simultaneous measurement of apoE-deficient, apoE-containing, and total HDL-cholesterol. Clin Chim Acta. 454:135-42, 2016
Watanabe M, Fuda H, Okabe H, Joko S, Miura Y, Hui SP, Yimin, Hamaoka N, Miki E, Chiba H. Oyster extracts attenuate pathological changes in non-alcoholic steatohepatitis (NASH) mouse model. J Funct Foods. 20:516-531, 2016
Furukawa T, Fuda H, Miyanaga S, Watanabe C, Chiba H, Hui SP.Rapid tin-mediated access to a lysophosphatidylethanolamine (LPE) library: Application to positional LC/MS analysis for hepatic LPEs in non-alcoholic steatohepatitis model mice.Chem Phys Lipids. 200:133-138, 2016
Okabe H, Hui SP, Fuda H, Furukawa T, Takeda S, Shrestha R, Miura Y, Watanabe M, Chiba H. Mass Spectrometric Quantification of Amphipathic, Polyphenolic Antioxidant of the Pacific Oyster (Crassostrea gigas). Anal Sci. 31:1341-4, 2015
Takeda S, Subagyo A, Hui SP, Fuda H, Shrestha R, Sueoka K, Chiba H. Elastic modulus of low-density lipoprotein as potential indicator of its oxidation. Ann Clin Biochem. 52:647-53, 2015
Matsuo J, Nakamura S, Takeda S, Ishida K, Yamazaki T, Yoshida M, Chiba H, Hui SP, Yamaguchi H. Synergistic Costimulatory Effect of Chlamydia pneumoniae with Carbon Nanoparticles on NLRP3 Inflammasome-Mediated Interleukin-1β Secretion in Macrophages. Infect Immun. 83:2917-25, 2015
Shrestha R, Hui SP, Miura Y, Yagi A, Takahashi Y, Takeda S, Fuda H, Chiba H. Identification of molecular species of oxidized triglyceride in plasma and its distribution in lipoproteins. Clin Chem Lab Med. 53:1859-69, 2015
Fuda H*, Watanabe M*, Hui SP*, Joko S, Okabe H, Jin S, Takeda S, Miki E, Watanabe T, Chiba H (*These authors contributed equally to the work). Anti-apoptotic effects of novel phenolic antioxidant isolated from the Pacific oyster (Crassostrea gigas) on cultured human hepatocytes under oxidative stress. Food Chem. 176:226-33, 2015
Shrestha R, Hui SP*, Imai H, Hashimoto S, Uemura N, Takeda S, Fuda H, Suzuki A, Yamaguchi S, Hirano K, Chiba H.(* Corresponding author). Plasma capric acid concentrations in healthy subjects determined by UV-labeled HPLC. Ann Clin Biochem. 52:588-96, 2015
Nagasaka H, Tsukahara H, Okano Y, Hirano KI, Sakurai T, Hui SP, Ohura T, Usui H, Yorifuji T, Hirayama S, Ohtake A, Miida T.Changes of lipoproteins in phenylalanine hydroxylase-deficient children during the first early of life. Clinica Chimica Acta. 433:1-4, 2014
Shrestha R, Hui SP, Sakurai T, Yagi A, Takahashi Y, Takeda S, Jin S, Fuda H, Chiba H. Identification of molecular species of cholesteryl ester hydroperoxides in very low-density and intermediate-density lipoproteins. Ann Clin Biochem. 51:662-71, 2014
Hirano K, Tanaka T, Ikeda Y, Yamaguchi S, Zaima N, Kobayashi K, Suzuki A, Sakata Y, Sakata Y, Kobayashi K, Toda T, Fukushima N, Ishibashi-Ueda H, Tavian D, Nagasaka H, Hui SP, Chiba H, Sawa Y, Hori M. Genetic mutations in adipose triglyceride lipase and myocardial up-regulation of peroxisome proliferated activated receptor-γ in patients with triglyceride deposit cardiomyovasculopathy. Biochem Biophys Res Commun. 443:574-9, 2014
Ohkawa F, Takeda S, Hui SP, Sakurai T, Jin S, Fuda H, Sueoka K, Chiba H. Evaluation of antioxidant activity of natural and synthetic compounds against LDL oxidation using CNT electrodes. IEEE Sensors J. 14:532-7, 2014
Nishimukai M, Maeba R, Ikuta A, Asakawa N, Kamiya K, Yamada S, Yokota T, Sakakibara M, Tsutsui H, Sakurai T, Takahashi Y, Hui SP, Chiba H, Okazaki T, Hara H. Serum choline plasmalogens-those with oleic acid in sn-2-are biomarkers for coronary artery disease. Clin Chim Acta. 437:147-54, 2014
Nishimukai M, Maeba R, Yamazaki Y, Nezu T, Sakurai T, Takahashi Y, Hui SP, Chiba H, Okazaki T, Hara H. Serum choline plasmalogens, particularly those with oleic acid in sn-2, are associated with proatherogenic state. J Lipid Res. 55:956-65, 2014
Takeda S, Hui SP, Fuda H, Jin S, Sakurai T, Ishii A, Mukasa K, Sueoka K, Chiba H. Evaluation of various electrode materials for detection of oxidized low-density lipoproteins. J Biomed Nanotechnol. 9:303-6, 2013
Jin S, Wada N, Takahashi Y, Hui SP, Sakurai T, Fuda H, Takeda S, Fujikawa M, Yanagisawa K, Ikegawa S, Kurosawa T, Chiba H. Quantification of urinary 18-hydroxycortisol using LC-MS/MS. Ann Clin Biochem. 50:450-6, 2013
Sakurai T, Takeda S, Takahashi JY, Takahashi Y, Wada N, Trirongjitmoah S, Namita T, Jin S, Ikuta A, Furumaki H, Hui SP, Fuda H, Fujikawa M, Shimizu K, Chiba H. Measurement of single low-density lipoprotein particles by atomic force microscopy. Ann Clin Biochem. 50:564-70, 2013
Sakurai T, Wada N, Takahashi Y, Ichikawa A, Ikuta A, Furumaki H, Hui SP, Jin S, Takeda S, Fuda H, Fujikawa M, Shimizu C, Nagasaka H, Furukawa H, Kobayashi S, Chiba H. Immunological detection of large oxidized lipoproteins in hypertriglyceridemic serum. Ann Clin Biochem. 50:465-72, 2013
Takeda S, Ohkawa F, Hui SP, Sakurai T, Jin S, Fuda H, Sueoka K, Chiba H. Evaluation of oxidized low-density lipoproteins using Kelvin Force microscopy. IEEE SENSORS JOURNAL. 13:3449-53, 2013
Hui SP, Sakurai T, Takeda S, Jin S, Fuda H, Kurosawa T, Chiba H. Analysis of triacylglycerol hydroperoxides in human lipoproteins by Orbitrap mass spectrometer. Anal Bioanal Chem. 405:4981-7, 2013
Hui SP, Hirano K, Shrestha R, Suzuki A, Yamaguchi S, Nagasaka H, Fukuzawa S, Chiba H:Analysis of triglycerides in skin fibroblast from TGCV by LC/MS. The 2nd International Symposiun on Triglyceride Deposit Cardiomyovasculopathy/Neutral Lipid Storage Disease, Osaka, 2013.4.
Shrestha, Hui SP, Sakurai T, Takahashi Y, Ohkawa F, Miyazaki R, N.Xiao, Takeda S, Jin S, Fuda H, Chiba H:Qualitative Determination of Triacylglycerol Hydroperoxide in VLDL, Intermediate Density Lipoprotein and Human Plasma using Orbitrap Mass Spectrometer. アメリカ臨床化学会(AACC), ヒューストン USA, 2013.7.
Watanabe M, Fuda H, Jin S, Sakurai T, Ohkawa F, Hui SP, Takeda S, Watanabe T, Koike T, Chiba H. Isolation and characterization of a phenolic antioxidant from the Pacific oyster (Crassostrea gigas). J Agric Food Chem. 60:830-5, 2012
Hui SP, Taguchi Y, Takeda S, Ohkawa F, Sakurai T, Yamaki S, Jin S, Fuda H, Kurosawa T, Chiba H. Quantitative determination of phosphatidylcholine hydroperoxides during copper oxidation of LDL and HDL by liquid chromatography/mass spectrometry. Anal Bioanal Chem. 403:1831-40, 2012
Yoshida S, Mohamed RH, Kajikawa M, Koizumi J, Tanaka M, Fugo K, Otsuka N, Maenaka K, Yagita H, Chiba H, Kasahara M.Involvement of an NKG2D ligand H60c in epidermal dendritic T cell-mediated wound repair. J Immunol 188:3972-3979,2012.
Hui SP, Sakurai T, Ohkawa F, Furumaki H, Jin S, Fuda H, Takeda S, Kurosawa T, Chiba H. Detection and characterization of cholesteryl ester hydroperoxides in oxidized LDL and oxidized HDL by use of an Orbitrap mass spectrometer. Anal Bioanal Chem. 404:101-12, 2012
Sakurai T, Ichikawa A, Furukawa H, Wada N, Nagasaka A, Takahashi Y, Fujikawa M, Ikuta A, Furumaki H, Shiga M, Shimizu C, Hui SP, Jin S, Takeda S, Fuda H, Nagasaka H, Kobayashi S, Chiba H. Novel monoclonal antibody recognizing triglyceride-rich oxidized LDLs associated with severe liver disease and small oxidized LDLs in normal subjects. Ann Clin Biochem. 49:456-62, 2012
Takeda S, Hui SP, Fukuda K, Fuda H, Jin S, Sakurai T, Ishii A, Mukasa K, Sueoka K, Chiba H. Detection of oxidized LDL using a carbon nanotube electrode. Sensor Actuator B Chem. 167:833-6, 2012
Hirata H, Takazumi K, Segawa S, Okada Y, Kobayashi N, Shigyo T, Chiba H. Xanthohumol, a prenylated chalcone from Humulus lupulus L., inhibits cholesteryl ester transfer protein. Food Chem. 134:1432-7, 2012.
Hirata H, Yimin, Segawa S, Ozaki M, Kobayashi N, Shigyo T, Chiba H. Xanthohumol prevents atherosclerosis by reducing arterial cholesterol Content via CETP and apolipoprotein E in CETP-transgenic mice. PLoS ONE. 7:e49415, 2012.
Watanabe M, Fuda H, Jin S, Sakurai T, Hui SP, Takeda S, Watanabe T, Koike T, Chiba H. A phenolic antioxidant from the Pacific oyster (Crassostrea gigas) inhibits oxidation of cultured human hepatocytes mediated by diphenyl-1-pyrenylphosphine. Food Chem. 134:2086-9, 2012
Nagasaka H, Yorifuji T, Takatani T, Okano Y, Tsukahara H, Yanai H, Hirano K, Hui SP, Hirayama S, Ito T, Chiba H, Miida T. CD36 deficiency predisposing young children to fasting hypoglycemia. Metabolism. 60:881-7, 2011
Tsuchida S, Kawamoto K, Nunome K, Hamaue N, Hui SP, Murai T, Aoki T, Kurosawa T. Chiral separation, determination of absolute configuration, and high performance liquid chromatography detection of enantiomeric 3-hydroxy hexadecanoyl-CoA. J Oleo Sci. 60:87-92, 2011
Higashi T, Ichikawa T, Shimizu C, Nagai S, Inagaki S, Min JZ, Chiba H, Ikegawa S, Toyo’oka T: Stable isotope-dilution liquid chromatography/tandem mass spectrometry method for determination of thyroxine in saliva. J Chromatogr B Analyt Technol Biomed Life Sci. 879:1013-1017, 2011.
Hui SP, Chiba H, Kurosawa T. Liquid chromatography-mass spectrometric determination of plasmalogens in human plasma. Anal Bioanal Chem. 400:1923-31, 2011
Hira T, Mori N, Nakamori T, Furuta H, Asano K, Chiba H, Hara H. Acute effect of soybean beta-conglycinin hydrolysate ingestion on appetite sensations in healthy humans. Appetite. 57: 765-768, 2011.
Hui SP, Chiba H, Jin S, Nagasaka H, Kurosawa T. Analyses for phosphatidylcholine hydroperoxides by LC/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 878:1677-82, 2010
Sakurai T, Trirongjitmoah S, Nishibata Y, Namita T, Tsuji M, Hui SP, Jin S, Shimizu K, Chiba H. Measurement of lipoprotein particle sizes using dynamic light scattering. Ann Clin Biochem. 47:476-81, 2010