Embedded Files
My team applies the power of in vivo and in vitro models to explore the impact of mechanical integrity on cardiac morphogenesis during heart development.
In vivo research theme: We apply our expertise to several transgenic animal models with mutations in desmosome-related genes.
Single cell RNA sequencing
Single cell RNA sequencing
Microdissection and culture
Microdissection and culture
of embryonic heart
of embryonic heart
Electron microscopy
Electron microscopy
Immuno-histological analysis
Immuno-histological analysis
in vitro research theme: We develop iPSC-derived Cardiomyocytes to model desmosome-related mutations.
dsg2IPSC-cm-day8-75k12.mp4Cardiomyocytes
Cardiomyocytes
8 days old contractile cardiomyocytes
alpha-Actinin (Red) ; Troponin I (Green)
alpha-Actinin (Red) ; Troponin I (Green)
Desmoplakin (Green); Desmoglein 2 (Red)
Desmoplakin (Green); Desmoglein 2 (Red)
iPSC derived Epicardial cells
Wt-1 (Green) ZO-1 (red)
Wt-1 (Green) ZO-1 (red)
Keratin network (Green)
Keratin network (Green)
Page updated
Google Sites
Report abuse