2025
Kim, D., Nam, H.J. and Baek, S.H. (2025). Ubiquitination of transcription factors in cancer: unveiling therapeutic potential. Molecular Oncology, doi: 10.1002/1878-0261.70033, link
Nam, H.J., Han, J.H., Yu, J., Cho, C.S., Kim, D., Kim, Y.E., Kim, M.J., Kim, J.H., Jo, D.H., Bae, S. (2025). Autophagy induction enhances homologous recombination-associated CRISPR–Cas9 gene editing. Nucleic Acids Research, (53), gkaf258, doi.org/10.1093/nar/gkaf258 link
2024
Kim, J.B., Yu, Y.S., Choi, Y.H., Lee, D.H., Han, S.B., Kwon, J.H., Noda, T., Ikawa, M., Kim, D., Kim H.K., Ballabio, A., Kim, K.I., and Baek, S.H. ( (2024). USF2 and TFEB compete in regulating lysosomal and autophagy genes. Nature Communications, 15(8334), doi.org/10.1038/s41467-024-52600-2 link
2023
Kim, JJ., Park, JH., Kim, H., Sim, W-S., Hong, S., Choi, Y-J., Kim, H-J., Lee, SM., Kim, D., Kang, S-w., Ban, K., Park, H-J. (2023). Vascular regeneration and skeletal muscle repair induced by long-term exposure to SDF-1α derived from engineered mesenchymal stem cells after hindlimb ischemia. Experimental & Molecular Medicine (EMM) 55, 2248–2259, doi.org/10.1038/s12276-023-01096-9 link
Kim, D., Nam, H.J. and Baek, S.H. (2023). Post-translational modifications of lysine-specific demethylase 1. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1866(4), doi:10.1016/j.bbagrm.2023.194968 link
Kang, J.-S.*, Kim, D.*, Rhee, J.*, Seo, J.-Y., Kim, J.-H., Lee, D., Lee, W., Kim, Y.L., Yoo, K., Bae, S., Chung, J., Seong, R.H., and Kong, Y.-Y. (* co-first authors) (2023). Baf155 regulates skeletal muscle metabolism via HIF-1a signaling. PLOS BIOLOGY. 21(7): e3002192, doi:10.1371/journal.pbio.3002192 link
2022
Kim, D. and Nam, H.J. (2022). PARP Inhibitors: Clinical Limitations and Recent Attempts to Overcome Them. International Journal of Molecular Sciences. 23(15), 8412; doi:10.3390/ijms23158412. link
Kim, D.*, Kim, J.*, Yu, Y.S., Kim, Y.R., Baek, S.H. and Won, K.-J. (* co-first authors) (2022). Systemic approaches using single cell transcriptome reveal that C/EBP γ regulates autophagy under amino acid starved condition. Nucleic Acids Research, 50(13), gkac593, doi:10.1093/nar/gkac593. link
2021
Kim, D., Kim, K.I., and Baek, S.H. (2021). Roles of Lysine-Specific Demethylase 1 (LSD1) in Homeostasis and Diseases. Journal of Biomedical Science, 28(41), doi:10.1186/s12929-021-00737-3. link
2020
Yu, Y.S.*, Shin, H.R.*, Kim, D.*, Baek, S.A., Choi, S.A., Ahn, H.J., Shamim, A., Kim, J.H., Kim, I.S., Kim, K.K., Won, K.-J., and Baek, S.H. (2020). Pontin Arginine Methylation by CARM1 Is Crucial for Epigenetic Regulation of Autophagy. Nature Communications, 11, 6297 (*co-first authors) link
Hong, K.S., Ahn, J.H., Jang, J.G., Lee, J.H., Kim H.N.*, Kim D.* and Lee, W.* (2020). GSK-LSD1, an LSD1 Inhibitor, Quashes SARS-CoV-2-triggered Cytokine Release Syndrome in vitro. Signal Transduction and Targeted Therapy, 5, 267 (*co-corresponding authors ) link
2019
Oh, S.K.*, Kim, D.*, Kim, K.K., Boo, K.J., Yu, Y.S., Kim, I.S., Jeon, Y., Lee, H., Im, S.-K., Lee, S.-H., Lee, J.M., Ko, Y.H., Park, D.C., Fang, S.S., and Baek, S.H. (2019). RORα Is Crucial for Attenuated Inflammatory Response to Maintain Intestinal Homeostasis. Proc. Natl. Acad. Sci. USA, doi: 10.1073/pnas.1907595116. (*co-first authors) link
2018
Kim, H.*, Kim, D.*, Choi, S.A., Kim, C.R., Oh, S.K., Pyo, K.E., Kim, J., Lee, S.-H., Yoon, J.-B., Zhang, Y., and Baek, S.H. (2018). KDM3A Histone Demethylase Functions as an Essential Factor for Activation of JAK2-STAT3. Proc. Natl. Acad. Sci. USA, doi: 10.1073/pnas.1805662115. (*co-first authors) link
Kim, D.*, Nam, H.J.*, Lee, W., Yim, H.Y., Ahn, J.Y., Park, S.W., Shin, H-J., Yu, R., Won, K.J., Bae, J.S., Kim, K.I., and Baek, S.H. (2018). PKCa-LSD1-NF-kB signaling cascade is crucial for epigenetic control of the inflammatory response. Molecular Cell 69. 398-411 (*co-first authors) link
2010 - 2017
Lim, C.-S., Nam, H.J., Lee, J.H., Kim, D., Choi, J.E., Kang, S.J., Kim, S.M., Kim, H.P., Kwak, C.J., Shim, K.-W., Kim, S.Y., Ko, H.-G., Lee, R.U., Jang, E.-H., Yoo, J.Y., Shim, J.H., Islam, M.A., Lee, Y.-S., Lee, J.-H., Baek, S.H., and Kang, B.-K. (2017). PKCα-mediated phosphorylation of LSD1 is required for presynaptic plasticity and hippocampal learning and memory. Scientific Reports 7(4912), doi: 10.1038/s41598-017-05239-7.
Kim, Y., Nam, H.J., Lee, J., Park, D.Y., Kim, C., Yu, Y.S., Kim, D., Park, S.W., Bhin, J., Hwang, D., Lee, H., Koh, G.Y. and Baek, S.H. (2016). Methylation-dependent regulation of HIF-1α stability restricts retinal and tumor angiogenesis. Nature Communications 7, doi:10.1038/ncomms10347
Nam, H.J., Boo, K., Kim, D., Han, D. H., Choe, H. K., Kim, C. R., Sun, W., Kim, H., Kim, K., Lee, H., Metzger, E., Schuele, R., Yoo, S., Takahashi, J. S., Cho, S., Son, G. H., and Baek, S. H. (2014). Phosphorylation of LSD1 by PKCα is crucial for circadian rhythmicity and phase resetting. Molecular Cell 53, 791-805 (Cover article, Faculty of 1000 Recommended)
Kim, B., Nam, H. J., Pyo, K. E., Jang, M. J., Kim, I. S., Kim, D., Boo, K., Lee, S. H., Yoon, J. B., Baek, S. H., and Kim, J. H. (2011). Breast cancer metastasis suppressor 1 (BRMS1) is destabilized by the Cul3-SPOP E3 ubiquitin ligase complex. Biochem. Biophys. Res. Comm. 415, 720-726.
Choi, H. J., Lee, J. M., Kim, H. K., Nam, H. J., Shin, H. J., Kim, D., Ko, E. Y., Noh, D. Y., Kim, K. I., Kim, J. H., and Baek, S. H. (2010). Bcl3-dependent stabilization of CtBP1 is crucial for the inhibition of apoptosis and tumor progression in breast cancer. Biochem. Biophys. Res. Comm. 400, 396-402.