Resourses

1. Molecular tools developed for systems biology:

Functional library of d-siRNAs targeting for 2,304 human signaling proteins

Functional library of ~1,000 full-length human small GTPase, GEFs , and GAPs constructs

Functional library of ~500 human and mouse serine/threoine and tyrosine kinases

Functional libraries of ~1000 human signaling domains

Human Orfeome library for ~15,000 human full-length proteins

2. Imaging systems used for the studies:

InCell Anayzer 1000; automated high-throughput fixed and live cell imaging and analysis system

Nikon A1R confocal; real-time live cell imaging, FRET, FRAP, and so on

Nikon TIRFM (Total Internal Refelection Fluoresent Microscope; real-time plasma membrane and cell contact area imaging

Fluorescent microscopes with DSU; fixed and live-cell wide field imaging & long time-lapse imaging