Overview
The global topical adhesives market is projected to expand at a CAGR of around 6% over the next five years, supported by several converging clinical, technological, and structural shifts in healthcare. Increasing volumes of surgical procedures worldwide, the steady adoption of advanced wound closure technologies by surgeons, and the growing acceptance of adhesives in both traditional and emerging clinical applications are all reinforcing demand.

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The continued rise of ambulatory surgical centers (ASCs) and outpatient care facilities, driven by the healthcare industry’s movement toward cost-effective and minimally invasive procedures, is accelerating the transition from conventional suturing to more efficient wound closure methods. Meanwhile, the expanding role of specialized, niche adhesive products is anticipated to further stimulate market penetration as surgeons seek tailored solutions for specific cases and patient needs.

Topical adhesives—primarily cyanoacrylate-based formulations—are designed to approximate wound edges efficiently while providing a protective microbial barrier. Their ability to rapidly seal wounds without the need for external dressings makes them a valuable component of modern surgical practice. Beyond simple wound approximation, these adhesives enhance cosmetic outcomes, support tissue strength when paired with sutures, and facilitate faster recovery by reducing discomfort and the need for prolonged wound care. Their adaptability allows their use across small, medium, and large wound categories, including scenarios where supportive mesh or adjunctive materials are needed. Topical adhesives have found strong relevance in orthopedic surgery, pediatric procedures, aesthetic operations, trauma care, and minimally invasive approaches where optimizing healing and patient satisfaction is crucial.

Increased Surgeon Adoption is Driving Incremental Growth
Surgeon acceptance of topical adhesives has grown gradually yet consistently, supported by over two decades of clinical familiarity and continuous improvements in formulation, ease of use, and device design. One of the key factors encouraging adoption is the substantial time savings compared to traditional suturing. While sutures may take several minutes to place, topical adhesives can be applied within 15–20 seconds, significantly reducing operative time—particularly in high-volume environments. Additionally, these adhesives serve as a microbial barrier, protecting wound sites from contamination and reducing postoperative infection risks.
Modern adhesive applicators have further enhanced uniformity and precision, making the application process intuitive even for users with limited experience. Younger surgeons, in particular, exhibit stronger receptivity to innovative wound closure methods and often incorporate adhesives into their workflow to improve efficiency. In many cases, wound closure using adhesives can be delegated to trained nursing staff, allowing the surgeon to proceed to the next procedure sooner. Although adhesives may add cost when used as adjuncts to sutures, their clinical and operational benefits—including time savings, better cosmetic outcomes, fewer complications, and improved patient comfort—justify their expanding role in surgical practice. As these advantages continue to gain recognition, surgeon adoption is expected to rise further.

Rise in Ambulatory Surgical Centers (ASC) and Outpatient Care to Drive Market Growth
The rapid growth of the ASC sector is emerging as a major catalyst for topical adhesive utilization. A significant portion of surgical procedures is shifting out of traditional hospitals and into ASCs due to their lower costs, shorter wait times, and patient-friendly environments. Insurers and payers are actively supporting this migration because procedures performed in ASCs tend to be more economical while yielding comparable or better outcomes.
At the same time, urgent care centers and retail clinics—including pharmacy-based care models—are expanding their roles within the healthcare continuum, offering convenient access points for minor injuries and simple surgical repairs. With private equity investments rising, particularly in the U.S. urgent care market where such firms account for nearly 18% of more than 14,000 urgent care centers as of mid-2025, the ecosystem is rapidly evolving.
Topical adhesives fit naturally within this care model due to their speed, ease of use, and the ability to reduce the need for follow-up visits. ASCs and urgent care settings prioritize fast healing, simplified wound management, and minimal complications, making adhesives an ideal choice over or alongside sutures. As patient volume increases within these decentralized care environments, demand for adhesives is expected to strengthen substantially.

Competitive Landscape Analysis
The global topical adhesives market includes a mix of well-established companies and emerging players focused on expanding their portfolios and geographic reach.
• Ethicon (Johnson & Johnson Surgical Technologies)
• Advanced Medical Solutions Group plc
• CHEMENCE
• B. Braun SE
• Medline Industries, LP
• Meril
• Sylke
• H.B. Fuller
• Baxter
• Klinion

These organizations are investing in next-generation adhesive formulations, expanding manufacturing capabilities, forming strategic alliances, and launching products tailored for specific clinical needs. Product innovation, regulatory approvals, and global distribution expansion remain essential strategies for maintaining competitiveness in this rapidly evolving space.

Market Drivers
Growth in surgical procedure volumes
Increased surgeon adoption of advanced technologies
Expansion into new clinical applications
Rise in ambulatory surgical centers (ASC) and outpatient care
Shift toward minimally invasive and outpatient procedures
Potential rise in uptake of niche products

Attractive Opportunities
Next-generation bio-adhesives and sealants
Combination products
Integration with minimally invasive and robotic surgery
Emerging markets

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Medi-Tech Insights is a healthcare-focused business research & insights firm. Our clients include Fortune 500 companies, blue-chip investors & hyper-growth start-ups. We have completed 100+ projects in Digital Health, Healthcare IT, Medical Technology, Medical Devices & Pharma Services in the areas of market assessments, due diligence, competitive intelligence, market sizing and forecasting, pricing analysis & go-to-market strategy. Our methodology includes rigorous secondary research combined with deep-dive interviews with industry-leading CXO, VPs, and key demand/supply side decision-makers.