The Global e-Prescribing Market Poised for Strong 24–26% Growth by 2029
The global e-prescribing market is on track to grow at a rapid CAGR of 24–26% through 2029, driven by the rising emphasis on patient safety, the need to eliminate medication errors, real-time clinical alerts, and improved prescription tracking.

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Post-pandemic digital acceleration, supportive regulations across various countries, increasing telemedicine adoption, government incentives, and the expanding use of electronic health record (EHR) systems are further propelling the market. Despite this momentum, limited digital literacy among certain end-user groups remains a key barrier to broader adoption.

Understanding e-Prescribing
e-Prescribing enables healthcare providers to send accurate, legible, and real-time prescriptions electronically to pharmacies from the point of care. This digital approach reduces manual errors, enhances patient safety, and streamlines the overall prescription workflow.

COVID-19 Accelerated the Shift Toward Digital Prescribing
The pandemic reshaped healthcare delivery worldwide, introducing widespread telehealth adoption and minimizing face-to-face patient–provider interactions. In this context, e-prescribing emerged as a critical tool to maintain safe, contactless care. With lockdowns and social distancing in effect, the need to avoid paper-based prescriptions surged. Data from Surescripts highlights a 72.5% rise in electronic prescriptions issued through telehealth during the first month of the pandemic—signaling a pivotal shift in prescribing behavior across the United States.

Regulatory Momentum Supporting e-Prescribing Adoption
Several countries introduced regulatory reforms to expand safe access to care and strengthen prescription oversight:
• In the United States, numerous states—including California, Indiana, Maryland, Michigan, Nebraska, New Hampshire, Utah, and Washington—implemented mandates requiring controlled substances to be prescribed electronically, helping to reduce drug misuse and overdose.
• In Ireland, amendments to the Medicinal Products Regulations enabled prescriptions to be transferred electronically using the Healthmail system. Hard-copy prescriptions were no longer required, and prescription validity was extended from six to nine months.
• Australia legalized electronic prescribing for Pharmaceutical Benefits Scheme (PBS) medicines, supported by parallel updates to state and territorial legislation.
• In August 2023, DrFirst and MEDITECH announced a collaboration to support e-prescribing for hospitals using the Expanse EHR in Canada, aligned with Canada Health Infoway’s PrescribeIT initiative.

Key Benefits Fueling Market Expansion
Growing digital adoption across healthcare continues to strengthen demand for e-prescribing. Major advantages include:
• Reduced Pharmacist Errors: Clear, standardized electronic prescriptions lessen interpretation errors associated with handwritten notes.
• Real-time Clinical Alerts: Systems notify prescribers of allergies, drug interactions, duplicate therapies, and contraindications, significantly improving patient safety.
• Prescription Fulfillment Monitoring: Clinicians can track whether patients have filled their prescriptions, supporting medication adherence.
• Instant Access to Medication History: Providers can review complete medication records instantly, saving time and enabling informed decisions.
• Enhanced Efficiency: Bulk prescription refills and automation streamline workflows, reduce manual steps, and decrease error rates.
• Elimination of Lost Prescriptions: Electronic transmission ensures patients do not misplace prescriptions, reducing administrative burdens for both clinics and pharmacies.
A senior leader from a major U.S. e-prescribing service provider emphasized that Electronic Prescribing for Controlled Substances (EPCS) mandates—now active in over half of U.S. states—are instrumental in reducing overdose-related deaths and will continue to drive market adoption.

Product Segment Overview
The market is divided into solutions and services:
• Solutions: These include software platforms that enable prescription generation, clinical decision support, medication history review, and pharmacy communication. This segment leads the market due to widespread EHR adoption and the need for seamless, error-free workflows.
• Services: Cover implementation, training, maintenance, and support necessary for optimized system performance. Although smaller in market share, services remain critical for successful deployment and long-term efficiency.

End-User Segment Outlook
The e-prescribing market serves three primary end-user groups:
• Hospitals: A major segment, driven by high prescription volumes, the need for integrated medication management, and strong alignment with EHR systems.
• Office-Based Physicians: A fast-growing user group adopting e-prescribing to streamline outpatient workflows and improve clinical efficiency.
• Pharmacies: Essential for completing the digital prescribing cycle, pharmacies benefit through error reduction, faster processing, and improved operations.

Competitive Landscape
Key players active in the global e-prescribing market include:
• Allscripts
• NextGen Healthcare
• AdvancedMD
• MDToolbox
• Practice Fusion
• DrFirst
• RXNT
• Chetu
• PrognoCIS
• NewCrop
• Among others

Growth Strategies Driving Market Expansion
Industry players are strengthening their market presence through strategic collaborations, acquisitions, and product innovation:
• April 2024: VieCure integrated DrFirst’s e-prescribing and medication management tools into its oncology decision support system.
• November 2023: Thoma Bravo completed a $1.8 billion acquisition of NextGen Healthcare to enhance its cloud-based healthcare portfolio.
• October 2023: Veradigm partnered with FDB to integrate the FDB Vela ePrescribing network into its EHR and ePrescribe solutions.
• March 2022: FDB launched FDB Vela, a cloud-native e-prescribing network enabling seamless clinical and medication data exchange.
• October 2021: Veradigm and CareMetx formed a strategic partnership to streamline specialty medication approval and improve patient care workflows.

Conclusion
The e-prescribing market is entering a high-growth phase fueled by strong regulatory support, the long-term impact of COVID-19 on telemedicine, increasing focus on controlled-substance safety, and the widespread digitization of healthcare workflows. As healthcare systems continue to prioritize safety, efficiency, and transparency, e-prescribing adoption is expected to accelerate considerably over the next several years.

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