Actin Polymerization

Actin dynamics and three different scales of actin filaments.

Actin polymerization is shown in approx 20 A cartoon structures of actin. Green blobs are ATP bound actin at the barbed end, engaging in active assembly, which is facilitated by profilin (red). Blue blobs are ADP bound actin at the pointed end, engaging in disassembly/ depolymerization, which is facilitated by cofilin (peach)