Lets look at some very common blues licks. Licks are usually just a few notes played together to make a 'statement'. They are often repeated to reinforce a them , and modified to form more of a conversation.
Im going to give some names to these just to make memorizing a bit easier
2 Root Jam - this using the 2 with various rhythms ... simple yet effective. 2 2 2b 2 2 2b 2
Good Morning - 1 2b 2
Im a man - 4b 3 2
Hoochie Coochie Man 3b 4b 3 2
Mannish Boy - 3b 4b 3b 3 2
Saints Up 2 3 4b 4
Saints Down 4 4b 3 2
Boogie Up 2 3 4 5b 5
Boogie Down 5 5b 4 3 2
4 draw shake 4 5 4 5 4 5 .......
4 blow shake 4b 5b 4b 5b .......
Juke 2 3 4 5 6 6