Publications
Noncoding RNA and Epigenetics
(*=(co)first, #=corresponding author)
2023-2024
Wei, G. 2024. RNA m6A modification, signals for degradation or stabilisation? Biochemical Society Transactions, 52(2):707-717 (Review) [PDF]
Xu H, Kong L, Cheng J, Moussawi KA, Chen X, Iqbal A, Wing PAC, Harris JM, Tsukuda S, Embarc-Buh A, Wei G, Castello A, Kriaucionis S, McKeating J, Lu X, and Song C-X. 2024. Absolute quantitative and base-resolution sequencing reveals comprehensive landscape of pseudouridine across the human transcriptome. BioRxiv.
2021 - 2022
Bowness JS, Nesterova TB, Wei G, Rodermund L, Almeida M, Coker H, Carter EJ, Kadaster A, and Brockdorff N. 2022. Xist-mediated silencing requires additive functions of SPEN and Polycomb together with differentiation-dependent recruitment of SmcHD1. Cell Reports, 39(7):110830 e8 [PDF] [bioRxiv preprint]
McManus CE, Mazzetto M, Wei G, Han M, and Reinke V. 2021. The zinc-finger protein OEF-1 stabilizes histone modification patterns and promotes efficient splicing in the Caenorhabditis elegans germ line. G3 Genes|Genomes|Genetics, 11(12):jkab329 [PDF]
Wei G, Almeida M, Pintacuda G, Coker H, Bowness JS, Ule J, and Brockdorff N. 2021. Acute depletion of METTL3 implicates N6-methyladenosine in alternative intron/exon inclusion in the nascent transcriptome. Genome Research, 31:1395-1408 [PDF] [bioRxiv preprint]
Rodermund L, Coker H, Oldenkamp R, Wei G, Bowness J, Rajkumar B, Nesterova T, Pinto DMS, Schermelleh L, and Brockdorff N. 2021. Time-resolved structured illumination microscopy reveals key principles of Xist RNA spreading. Science, 372, eabe7500 [PDF] [bioRxiv preprint] [Faculty Opinions Recommendation]
Wei G, Almeida M, Bowness JS, Neterova TB, and Brockdorff N. 2021. Xist Repeats B and C, but not Repeat A, mediate de novo recruitment of the Polycomb system in X chromosome inactivation. Developmental Cell, 56, 1234-1235 (Letter) [PDF]
2019 - 2020
Wei G, Brockdorff N#, and Zhang T#. 2020. The PWWP2A Histone Deacetylase Complex Represses Intragenic Transcription Initiation in mESCs. iScience, 23(11):101741 [PDF]
Wang D, Zhou Z, Wu E, Ouyang C, Wei G, Wang Y, He D, Cui Y, Zhang D, Chen X, Reed SH, Luo J, and Chen R. 2020. LRIK interacts with the Ku70-Ku80 heterodimer enhancing the efficiency of NHEJ repair. Cell Death and Differentiation, 27(12): 3337-3353 [PDF]
Brockdorff N#, Bowness JS, and Wei G#. 2020. Progress toward understanding chromosome silencing by Xist RNA. Genes & Development, 34:733-744 (Review) [PDF]
Coker H, Wei G, Moindrot B, Mohammed S, Nesterova TB, and Brockdorff N. 2020. The role of the Xist 5’ m6A region and RBM15 in X chromosome inactivation. Wellcome Open Research, 5:31 [PDF]
Nesterova TB*, Wei G*, Coker H*, Pintacuda G*, Bowness JS, Zhang T, Almeida M, Bloechl B, Moindrot B, Cater EJ, Alvarez Rodrigo I, Pan Q, Bi Y, Song CX, and Brockdorff N. 2019. Systematic Allelic Analysis Defines the Interplay of Key Pathways in X Chromosome Inactivation. Nature Comminucations, 10:3129 [PDF] [bioRxiv preprint] [F1000 Recommendation]
Wang S*, Zhang Y*, Huang J, Wong CC, Zhai J, Li C, Wei G, Zhao L, Wang G, Wei H, Zhao Z, and Yu J. 2019. TRIM67 suppresses colon tumorigenesis by interacting with p53 to prevent MDM2-mediated degradation. Cancer Research, 79, 4086-4098 [PDF]
Han M, Wei G, McManus CE, Hillier LW, and Reinke V. 2019. Isolated C. elegans germ nuclei exhibit distinct genomic profiles of histone modification and gene expression. BMC Genomics, 20, 500 [PDF] [bioRxiv preprint]
Coker H#, Wei G, and Brockdorff N. 2019. m6A modification of non-coding RNA and the control of mammalian gene expression. BBA - Gene Regulatory Mechanisms, 1862(3): 310-318 (Review) [PDF]
2017 - 2018
Zhang T*, Wei G*, Millard CJ, Fischer R, Konietzny R, Kessler BM, Schwabe JWR, and Brockdorff N. 2018. A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes. Nature Communications, 9:3798 [PDF]
Pintacuda G*, Wei G*, Roustan C, Kirmitzas BA, Solcan N, Cerase A, Castello A, Mohammed S, Moindrot B, Nesterova TB, and Brockdorff N. 2017. hnRNPK Recruits PCGF3/5-PRC1 to the Xist RNA B-Repeat to Establish Polycomb-Mediated Chromosomal Silencing. Molecular Cell, 68, 955–969 e10 [PDF] [Recommended by F1000]
Sun Y*, Wei G*, Luo H*, Wu W*, Skogerbø G, Luo J, and Chen R. 2017. The long noncoding RNA SNHG1 promotes tumor growth through regulating transcription of both local and distal genes. Oncogene, 36, 6774–6783 [PDF]
Han M, Zou W, Chang H, Yu Y, Zhang H, Li S, Cheng H, Wei G, Chen Y, Reinke V, Xu T, and Kang L. 2017. A systematic RNAi screen reveals a novel role of a spindle assembly checkpoint protein BuGZ in synaptic transmission in C. elegans. Frontiers in Molecular Neuroscience, 10: 141 [PDF]
2016 and before
Guo Y, Wang Z, Li Y, Wei G, Yuan J, Sun Y, Wang H, Qin Q, Zeng Z, Zhang S, and Chen R. 2016. Lateralization of gene expression in the honeybee brain during olfactory learning. Scientific Reports, 6:34727 [PDF]
Chen J, Liu L, Wei G, Wu W, Luo H, Yuan J, Luo J, and Chen R. 2016. The long noncoding RNA ASNR suppresses Bcl-2 mRNA degradation in apoptosis through affecting nuclei-cytoplasmic transportation of AUF1. Scientific Reports, 6:32189 [PDF]
Liu L, Yue H, Liu Q, Yuan J, Li J, Wei G, Chen X, Lu Y, Guo M, Luo J, and Chen R. 2016. LncRNA MT1JP functions as a tumor suppressor by interacting with TIAR to modulate the p53 pathway. Oncotarget, 7, 15787-15800 [PDF]
Wei G*, Luo H*, Sun Y*, Li J, Tian L, Liu W, Liu L, Luo J, He J, and Chen R. 2015. Transcriptome profiling of esophageal squamous cell carcinoma reveals a long noncoding RNA acting as a tumor suppressor. Oncotarget, 6, 17065-17080 [PDF]
Luo H*, Sun Y*, Wei G*, Luo J, Yang X, Liu W, Guo M, and Chen R. 2015. The Functional Characterization of Long Non-coding RNA Lnc_bc060912 in Human Lung Carcinoma Cells. Biochemistry, 54, 2895-2902 [PDF]
Xu D, Wei G, Lu P, Luo J, Chen X, Skogerbø G, and Chen R. 2014. Analysis of the p53/CEP-1 regulated non-coding transcriptome in C. elegans by an NSR-seq strategy. Protein & Cell, 5, 770-782 [PDF]
Chang H*, Han M*, Huang W*, Wei G, Chen J, Chen PR, Chen R, Zhang J, Xu T, and Xu P. 2013. Light-induced protein translocation by genetically encoded unnatural amino acid in Caenorhabditis elegans. Protein & Cell, 4, 883-886 [PDF]
Li A*, Wei G*, Wang Y, Zhou Y, Zhang XE, Bi L, and Chen R. 2012. Identification of Intermediate-Size Non-Coding RNAs Involved in the UV-Induced DNA Damage Response in C. elegans. PLoS One, 7, e48066 [PDF]
Sleumer MC, Wei G, Wang Y, Chang H, Xu T, Chen R, and Zhang MQ. 2012. Regulatory elements of Caenorhabditis elegans ribosomal protein genes. BMC Genomics, 13, 433 [PDF]
Xiao T, Wang Y, Luo H, Liu L, Wei G, Chen X, Sun Y, Chen X, Skogerbø G, and Chen R. 2012. A differential sequencing-based analysis of the C. elegans noncoding transcriptome. RNA, 18, 626-639 [PDF]
Wang Y*, Chen J*, Wei G, He H, Zhu X, Xiao T, Yuan J, Dong B, He S, Skogerbø G, and Chen R. 2011. The Caenorhabditis elegans intermediate-size transcriptome shows high degree of stage-specific expression. Nucleic Acids Research, 39, 5203-5214 [PDF]