How gene expression is regulated by RNA modifications and how this regulation controls cell fate transitions.
My research focuses on understanding how dynamic RNA modifications shape gene regulatory programs during cell fate transitions. Specifically, I investigate:
Where and how N6-methyladenosine (m6A) is installed on RNA transcripts.
How m6A deposition and activity are dynamically regulated across distinct cellular states.
The development of site-specific RNA modification editing tools to establish causal links between RNA modifications and cell fate transitions.