Some of the ongoing projects in the lab are
Some of the ongoing projects in the lab are
- Neuromodulatory environment's role on the determination of rhythm-generating network's stability - Neuromodulatory substances appear to determine what components a network is formed of. When the modulatory environment is perturbed the networks can reconfigure themselves. We want to know how this happens.
- Ionic current co-regulation - Ion channels are expressed in a coordinated fashion. We don't know what all the functional implications of this are.
- Neuromodulation of current co-regulation - The coordinated expression of ion channels depends on the neuron's voltage and also on the neuromodulatory environment, and we don't know virtually anything about the role of these neuromodulators in this.
- Circadian regulation of ionic currents - Coordinated expression of ionic currents appears to be regulated over a 24 hr period, at least in mammalian neurons. What consequences does this have for neuronal function?
- Neuromodulation of circadian rhythms - The circadian clock mechanism has been large figured out. However, how that is integrated to the rich neuromodulatory environment of the nervous system is not.
- Glia electrophysiology - Glia are about 10 times more abundant than neurons in the nervous system, and occupy about the same volume as neurons. Yet, their role in many instances is just beginning to be grasped. In crustaceans, the role of glia is virtually unknown.